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Outputs (165)

Population variability in animal health: Influence on dose-exposure-response relationships: Part II: Modelling and simulation (2018)
Journal Article
Martinez, M., Gehring, R., Mochel, J. P., Pade, D., & Pelligand, L. (2018). Population variability in animal health: Influence on dose-exposure-response relationships: Part II: Modelling and simulation. Journal of Veterinary Pharmacology and Therapeutics, 41(4), E-68. https://doi.org/10.1111/jvp.12666

During the 2017 Biennial meeting, the American Academy of Veterinary Pharmacology and Therapeutics hosted a 1‐day session on the influence of population variability on dose‐exposure‐response relationships. In Part I, we highlighted some of the source... Read More about Population variability in animal health: Influence on dose-exposure-response relationships: Part II: Modelling and simulation.

Outcome and prognostic factors in medically treated canine prostatic carcinomas: A multi-institutional study (2018)
Journal Article
Ravicini, S., Baines, S. J., Taylor, A., Amores-Fuster, I., Mason, S. L., & Treggiari, E. (2018). Outcome and prognostic factors in medically treated canine prostatic carcinomas: A multi-institutional study. Veterinary and Comparative Oncology, 16(4), 450-458. https://doi.org/10.1111/vco.12400

Literature describing medical treatment of canine prostatic carcinoma (PC) is sparse. The aims of this study were to assess outcomes, including time to progression (TTP) and median survival time (MST), of canine PC treated with non‐steroidal anti‐inf... Read More about Outcome and prognostic factors in medically treated canine prostatic carcinomas: A multi-institutional study.

Somatosensory and motor evoked potentials in dogs with chronic severe thoracolumbar spinal cord injury (2018)
Journal Article
Zu, H. Z., Jeffery, N. D., & Granger, N. (2018). Somatosensory and motor evoked potentials in dogs with chronic severe thoracolumbar spinal cord injury. https://doi.org/10.1016/j.tvjl.2018.05.007

ome dogs that become paraplegic after severe spinal cord injury regain ambulation on the pelvic limbs despite permanent loss of pelvic limb sensation, a phenomenon termed ‘spinal walking’. Plastic changes in spinal cord circuitry are thought to media... Read More about Somatosensory and motor evoked potentials in dogs with chronic severe thoracolumbar spinal cord injury.

Mineralization can be an incidental ultrasonographic finding in equine tendons and ligaments (2018)
Journal Article
O'Brien, E. J. O., & Smith, R. K. W. (2018). Mineralization can be an incidental ultrasonographic finding in equine tendons and ligaments. https://doi.org/10.1111/vru.12628

Tendon/ligament mineralization is recognized in horses but information regarding its clinical significance is limited. The aims of this observational study were to report the structures most commonly affected by ultrasonographically detectable minera... Read More about Mineralization can be an incidental ultrasonographic finding in equine tendons and ligaments.

C7 vertebra homeotic transformation in domestic dogs – are Pug dogs breaking mammalian evolutionary constraints? (2018)
Journal Article
Brocal, J., De Decker, S., José-López, R., Manzanilla, E. G., Penderis, J., Stalin, C., …Gutierrez-Quintana, R. (2018). C7 vertebra homeotic transformation in domestic dogs – are Pug dogs breaking mammalian evolutionary constraints?. Journal of Anatomy, https://doi.org/10.1111/joa.12822

The number of cervical vertebrae in mammals is almost constant at seven, regardless of their neck length, implying that there is selection against variation in this number. Homebox (Hox) genes are involved in this evolutionary mammalian conservation,... Read More about C7 vertebra homeotic transformation in domestic dogs – are Pug dogs breaking mammalian evolutionary constraints?.

Prognostic value of mitral annular systolic plane excursion and tricuspid annular plane systolic excursion in cats with hypertrophic cardiomyopathy (2018)
Journal Article
Spalla, I., Payne, J. R., Borgeat, K. A., Fuentes, V. L., & Connolly, D. J. (2018). Prognostic value of mitral annular systolic plane excursion and tricuspid annular plane systolic excursion in cats with hypertrophic cardiomyopathy. Journal of Veterinary Cardiology, 20(3), 154-164. https://doi.org/10.1016/j.jvc.2018.04.005

Hypertrophic cardiomyopathy (HCM) has a variable prognosis; left atrial size, presence of clinical signs and left ventricular systolic function have been shown to predict outcomes. Mitral annular plane systolic excursion (MAPSE) and tricuspid annular... Read More about Prognostic value of mitral annular systolic plane excursion and tricuspid annular plane systolic excursion in cats with hypertrophic cardiomyopathy.