Pathobiology and Population Sciences

Is Africa prepared for tackling the COVID-19 (SARS-CoV-2) epidemic? Lessons from past outbreaks, ongoing pan-African public health efforts, and implications for the future (2020)
Journal Article
Kapata, N., Ihekweazu, C., Ntoumi, F., Tajudeen, R., Chanda-Kapata, P., Mwaba, P., Mukonka, V., Bates, M., Tembo, J., Corman, V., Mfinanga, S., Asogun, D., Elton, L., Arruda, L. B., Thomason, M. J., Mboera, L., Yavlinsky, A., Haider, N., Simons, D., Hollmann, L., …Zumla, A. (2020). Is Africa prepared for tackling the COVID-19 (SARS-CoV-2) epidemic? Lessons from past outbreaks, ongoing pan-African public health efforts, and implications for the future. International Journal of Infectious Diseases, https://doi.org/10.1016/j.ijid.2020.02.049

Anthropogenic Threats to Wild Cetacean Welfare and a Tool to Inform Policy in This Area (2020)
Journal Article
Nicol, C., Bejder, L., Green, L., Johnson, C., Keeling, L., Noren, D., Van der Hoop, J., & Simmonds, M. (2020). Anthropogenic Threats to Wild Cetacean Welfare and a Tool to Inform Policy in This Area. Frontiers in Veterinary Science, 7, https://doi.org/10.3389/fvets.2020.00057

Human activities and anthropogenic environmental changes are having a profound effect on biodiversity and the sustainability and health of many populations and species of wild mammals. There has been less attention devoted to the impact of human acti... Read More about Anthropogenic Threats to Wild Cetacean Welfare and a Tool to Inform Policy in This Area.

Poultry Coccidiosis: Design and Interpretation of Vaccine Studies (2020)
Journal Article
Soutter, F., Werling, D., Tomley, F. M., & Blake, D. P. (2020). Poultry Coccidiosis: Design and Interpretation of Vaccine Studies. Frontiers in Veterinary Science, 7, https://doi.org/10.3389/fvets.2020.00101

Eimeria infection impacts upon chicken welfare and economic productivity of the poultry sector. Live coccidiosis vaccines for chickens have been available for almost 70 years, but the requirement to formulate blends of oocysts from multiple Eimeria s... Read More about Poultry Coccidiosis: Design and Interpretation of Vaccine Studies.

Passengers' destinations from China: low risk of Novel Coronavirus (2019-nCoV) transmission into Africa and South America (2020)
Journal Article
Haider, N., Yavlinsky, A., Simons, D., Osman, A. Y., Ntoumi, F., Zumla, A., & Kock, R. A. (2020). Passengers' destinations from China: low risk of Novel Coronavirus (2019-nCoV) transmission into Africa and South America. Epidemiology and Infection, 148, https://doi.org/10.1017/S0950268820000424

Novel Coronavirus (2019-nCoV [SARS-COV-2]) was detected in humans during the last week of December 2019 at Wuhan city in China, and caused 24 554 cases in 27 countries and territories as of 5 February 2020. The objective of this study was to estimate... Read More about Passengers' destinations from China: low risk of Novel Coronavirus (2019-nCoV) transmission into Africa and South America.

Mammalian lectin arrays for screening host-microbe interactions (2020)
Journal Article
Jégouzo, S. A. F., Nelson, C., Hardwick, T., Wong, S. T. A., Lau, N. K. K., Neoh, G. K. E., Castellanos-Rueda, R., Huang, Z., Mignot, B., Hirdaramani, A., Howitt, A., Frewin, K., Shen, Z., Fox, R. J., Wong, R., Ando, M., Emony, L., Zhu, H., Holder, A. L., Werling, D., …Drickamer, K. (2020). Mammalian lectin arrays for screening host-microbe interactions. Journal of Biological Chemistry, 295(14), 4541-4555. https://doi.org/10.1074/jbc.RA120.012783

Many members of the C-type lectin family of glycan-binding receptors have been ascribed roles in the recognition of microorganisms and serve as key receptors in the innate immune response to pathogens. Other mammalian receptors have become targets th... Read More about Mammalian lectin arrays for screening host-microbe interactions.

The prevalence and risk factors for human Brucella species infection in a cross-sectional survey of a rural population in Punjab, India (2020)
Journal Article
Mangtani, P., Berry, I., Beauvais, W., Holt, H. R., Kulashri, A., Bharti, S., Sagar, V., Nguipdop-Djomo, P., Bedi, J., Kaur, M., Guitian, J., McGiven, J., Kaur, P., Singh Gill, J. P., Grover, G. S., & Kumar, R. (2020). The prevalence and risk factors for human Brucella species infection in a cross-sectional survey of a rural population in Punjab, India. Transactions of The Royal Society of Tropical Medicine and Hygiene, https://doi.org/10.1093/trstmh/trz133

Brucellosis is an important neglected zoonosis. Effective cattle vaccines are available but are infrequently used in India, where rural households commonly own one or two cattle as sources of protein and income. We assessed the prevalence of infectio... Read More about The prevalence and risk factors for human Brucella species infection in a cross-sectional survey of a rural population in Punjab, India.

Serological survey of wild cervids in England and Wales for bovine viral diarrhoea virus (2020)
Journal Article
Hardstaff, J., Hunt, H., Tugwell, L., Thomas, C., Elattar, L., Brownlie, J., & Booth, R. E. (2020). Serological survey of wild cervids in England and Wales for bovine viral diarrhoea virus. Veterinary Record, https://doi.org/10.1136/vr.105527

Bovine viral diarrhoea (BVD) is a production disease commonly found in British cattle herds. Species other than cattle have been shown to be infected with the virus, thereby providing a potential source of infection for livestock. This study surveyed... Read More about Serological survey of wild cervids in England and Wales for bovine viral diarrhoea virus.

Evaluation of the Immunoprotective Potential of Recombinant Paraflagellar Rod Proteins of Trypanosoma evansi in Mice (2020)
Journal Article
Maharana, B. R., Sudhakar, N. R., Jawalagatti, V., Saravanan, B. C., Blake, D. P., & Tewari, A. K. (2020). Evaluation of the Immunoprotective Potential of Recombinant Paraflagellar Rod Proteins of Trypanosoma evansi in Mice. Vaccines, 8(1), 84. https://doi.org/10.3390/vaccines8010084

Trypanosomosis, caused by Trypanosoma evansi, is an economically significant disease of livestock. Systematic antigenic variation by the parasite has undermined prospects for the development of a protective vaccine that targets the immunodominant sur... Read More about Evaluation of the Immunoprotective Potential of Recombinant Paraflagellar Rod Proteins of Trypanosoma evansi in Mice.

Divergence across mitochondrial genomes of sympatric members of the Schistosoma indicum group and clues into the evolution of Schistosoma spindale (2020)
Journal Article
Jones, B. P., Norman, B. F., Borrett, H. E., Attwood, S. W., Mondal, M. M. H., Walker, A. J., Webster, J. P., Jayanthe Rajapakse, P. R. V., & Lawton, S. P. (2020). Divergence across mitochondrial genomes of sympatric members of the Schistosoma indicum group and clues into the evolution of Schistosoma spindale. https://doi.org/10.1038/s41598-020-57736-x

Schistosoma spindale and Schistosoma indicum are ruminant-infecting trematodes of the Schistosoma indicum group that are widespread across Southeast Asia. Though neglected, these parasites can cause major pathology and mortality to livestock leading... Read More about Divergence across mitochondrial genomes of sympatric members of the Schistosoma indicum group and clues into the evolution of Schistosoma spindale.

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