Outputs (214)

Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs (2017)
Journal Article
Lee, K. C. L., Baker, L., Mallett, S., Riddell, A., Chowdary, P., Alibhai, H. I. K., …Agarwal, B. (2017). Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs. https://doi.org/10.1038/s41598-017-09508-3

Increases in prothrombin time (PT) and international normalised ratio (INR) characterise acute liver injury (ALI) and failure (ALF), yet a wide heterogeneity in clotting abnormalities exists. This study defines evolution of coagulopathy in 10 pigs wi... Read More about Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs.

Sialylated glycosylphosphatidylinositols suppress the production of toxic amyloid-ß oligomers (2017)
Journal Article
Nolan, W., McHale-Owen, H., & Bate, C. (2017). Sialylated glycosylphosphatidylinositols suppress the production of toxic amyloid-ß oligomers. Biochemical Journal, 474(17), 3045-3058. https://doi.org/10.1042/BCJ20170239

The production of amyloid-β (Aβ) is a key factor driving pathogenesis in Alzheimer's disease (AD). Increasing concentrations of soluble Aβ oligomers within the brain lead to synapse degeneration and the progressive dementia characteristic of AD. Sinc... Read More about Sialylated glycosylphosphatidylinositols suppress the production of toxic amyloid-ß oligomers.

Gastric dilation-volvulus in dogs attending UK emergency-care veterinary practices: prevalence, risk factors and survival (2017)
Journal Article
O'Neill, D. G., Case, J., Boag, A. K., Church, D. B., McGreevy, P. D., Thomson, P. C., & Brodbelt, D. C. (2017). Gastric dilation-volvulus in dogs attending UK emergency-care veterinary practices: prevalence, risk factors and survival. Journal of Small Animal Practice, 58(11), 629-638. https://doi.org/10.1111/jsap.12723

Comparison of veterinary drugs and veterinary homeopathy: part 2 (2017)
Journal Article
Lees, P., Chambers, D., Pelligand, L., Toutain, P. L., Whiting, M., & Whitehead, M. L. (2017). Comparison of veterinary drugs and veterinary homeopathy: part 2. Veterinary Record, 181, 198-207. https://doi.org/10.1136/vr.104279

Part 2 of this narrative review outlines the theoretical and practical bases for assessing the efficacy and effectiveness of conventional medicines and homeopathic products. Known and postulated mechanisms of action are critically reviewed. The evide... Read More about Comparison of veterinary drugs and veterinary homeopathy: part 2.

Inferring within-herd transmission parameters for African swine fever virus using mortality data from outbreaks in the Russian Federation (2017)
Journal Article
Guinat, C., Porphyre, T., Gogin, A., Dixon, L., Pfeiffer, D. U., & Gubbins, S. (2017). Inferring within-herd transmission parameters for African swine fever virus using mortality data from outbreaks in the Russian Federation. Transboundary and Emerging Diseases, https://doi.org/10.1111/tbed.12748

Comparison of veterinary drugs and veterinary homeopathy: part 1 (2017)
Journal Article
Lees, P., Chambers, D., Pelligand, L., Toutain, P. L., Whiting, M., & Whitehead, M. L. (2017). Comparison of veterinary drugs and veterinary homeopathy: part 1. Veterinary Record, 181(7), 170-176. https://doi.org/10.1136/vr.104278

For many years after its invention around 1796, homeopathy was widely used in people and later in animals. Over the intervening period (1796-2016) pharmacology emerged as a science from Materia Medica (medicinal materials) to become the mainstay of v... Read More about Comparison of veterinary drugs and veterinary homeopathy: part 1.

Bactericidal and Anti-biofilm Effects of Polyhexamethylene Biguanide in Models of Intracellular and Biofilm of Staphylococcus aureus Isolated from Bovine Mastitis (2017)
Journal Article
Kamaruzzaman, N. F., Chong, S. Q. Y., Edmondson-Brown, K. M., Ntow-Boahene, W., Bardiau, M., & Good, L. (2017). Bactericidal and Anti-biofilm Effects of Polyhexamethylene Biguanide in Models of Intracellular and Biofilm of Staphylococcus aureus Isolated from Bovine Mastitis. Frontiers in Microbiology, 11(8), 1518. https://doi.org/10.3389/fmicb.2017.01518

Staphylococcus aureus infection is a common cause of mastitis, reducing milk yield, affecting animal welfare and causing huge economic losses within the dairy industry. In addition to the problem of acquired drug resistance, bacterial invasion into u... Read More about Bactericidal and Anti-biofilm Effects of Polyhexamethylene Biguanide in Models of Intracellular and Biofilm of Staphylococcus aureus Isolated from Bovine Mastitis.

Evidence for more cost-effective surveillance options for bovine spongiform encephalopathy (bse) and scrapie in Great Britain (2017)
Journal Article
Wall, B. A., Arnold, M. E., Radia, D., Gilbert, W., Ortiz-Pelaez, A., Staerk, K. D. C., …Guitian, J. (2017). Evidence for more cost-effective surveillance options for bovine spongiform encephalopathy (bse) and scrapie in Great Britain. Eurosurveillance, 22(32), 4. https://doi.org/10.2807/1560-7917.ES.2017.22.32.30594

Evidence for more cost-effective surveillance options for bovine spongiform encephalopathy (bse) and scrapie in Great Britain (2017)
Journal Article
Wall, B. A., Arnold, M. E., Radia, D., Gilbert, W., Ortiz-Pelaez, A., Staerk, K. D. C., …Guitian, J. (2017). Evidence for more cost-effective surveillance options for bovine spongiform encephalopathy (bse) and scrapie in Great Britain. Eurosurveillance, 22(32), 4. https://doi.org/10.2807/1560-7917.ES.2017.22.32.30594

Serum anti-Müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat (2017)
Journal Article
Heaps, L. A., Scudder, C. J., Lipscomb, V. J., Steinbach, S. M. L., Priestnall, S. L., Martineau, H., …Garden, O. A. (2017). Serum anti-Müllerian hormone concentrations before and after treatment of an ovarian granulosa cell tumour in a cat. Journal of Feline Medicine and Surgery Open Reports, 32(2), https://doi.org/10.1177/2055116917722701