Incidence and risk factors for neurological signs after attenuation of a single congenital portosystemic shunt in 50 cats.
Strickland, Rhiannon; Tivers, Michael S; Fowkes, Robert C; Lipscomb, Victoria J
Michael S Tivers
Robert C Fowkes
Victoria J Lipscomb
To determine the incidence, outcome, and risk factors for postattenuation neurological signs (PANS) in cats treated for single congenital portosystemic shunts (CPSS).
Retrospective cohort study.
Cats (n = 50) with a single CPSS.
Medical records of cats treated by surgical attenuation of a single CPSS between 2003 and 2017 were reviewed for signalment, surgical technique, preoperative management and postoperative clinical outcomes. Binary logistic regression was performed to investigate risk factors for occurrence of PANS and seizures.
Congenital portosystemic shunts in 50 cats included 40 extrahepatic and 10 intrahepatic shunts. Postattenuation neurological signs were recorded in 31 (62%) cats and graded as 1 in 10 cats, 2 in nine cats, and 3 in 12 cats. Postattenuation neurological signs included seizures in 11 cats. Five of 31 cats with PANS did not survive to discharge. No association was detected between PANS or seizures and the type of CPSS (intrahepatic or extrahepatic), degree of attenuation, age, or the use of perioperative levetiracetam or hepatic encephalopathy immediately preoperatively. Osmolality at a median 24?hours postoperatively was lower in cats with PANS (P?
Strickland, R., Tivers, M. S., Fowkes, R. C., & Lipscomb, V. J. (2020). Incidence and risk factors for neurological signs after attenuation of a single congenital portosystemic shunt in 50 cats. Veterinary Surgery, https://doi.org/10.1111/vsu.13489
|Journal Article Type||Article|
|Acceptance Date||May 13, 2020|
|Publication Date||Jul 21, 2020|
|Deposit Date||Aug 6, 2020|
|Publicly Available Date||Aug 6, 2020|
|Peer Reviewed||Peer Reviewed|