Antibiotic resistance gene sharing networks and the effect of dietary nutritional content on the canine and feline gut resistome

Kim, Y; Leung, M H Y; Kwok, W; Fournié, G; Li, J; Lee, P K H; Pfeiffer, D U

Abstract

As one of the most densely populated microbial communities on Earth, the gut microbiota serves as an important reservoir of antibiotic resistance genes (ARGs), referred to as the gut resistome. Here, we investigated the association of dietary nutritional content with gut ARG diversity and composition, using publicly available shotgun metagenomic sequence data generated from canine and feline fecal samples. Also, based on network theory, we explored ARG-sharing patterns between gut bacterial genera by identifying the linkage structure between metagenomic assemblies and their functional genes obtained from the same data.

Citation

Kim, Y., Leung, M. H. Y., Kwok, W., Fournié, G., Li, J., Lee, P. K. H., & Pfeiffer, D. U. (2020). Antibiotic resistance gene sharing networks and the effect of dietary nutritional content on the canine and feline gut resistome. https://doi.org/10.1186/s42523-020-0022-2

• Journal Article Type: Article
• Acceptance Date: Jan 29, 2020
• Publication Date: Feb 7, 2020
• Deposit Date: Feb 27, 2020
• Publicly Available Date: Nov 20, 2020
• Journal: Animal Microbiome
• Peer Reviewed: Peer Reviewed
• Volume: 2
• Issue: 4
• DOI: https://doi.org/10.1186/s42523-020-0022-2
• Public URL: https://rvc-repository.worktribe.com/output/1378721