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Abnormal platelet activity in dogs and cats – impact and measurement

Gant, P; McBride, D; Humm, K R


P Gant

D McBride

K R Humm


Abnormal platelet activity can either lead to bleeding tendencies or inappropriate thrombus formation and can occur secondarily to a wide variety of disease processes, with a range of clinical consequences and severity. This article will discuss the pathophysiology of platelet function abnormalities and consider a logical diagnostic approach applicable to veterinary practice. Recent advances in platelet function testing will then be discussed, with regards to detection of platelet dysfunction and tailoring of pharmacological manipulation. Although many of these tests are still confined to research or academic institutions, techniques for indirectly assessing platelet function are starting to become more widely available. Although we still require further research to develop guidelines for the use of these tests in clinical decision‐making, the recent advances in this field are an exciting step forward in being able to detect and manage platelet dysfunction in both primary care and referral practice.


Gant, P., McBride, D., & Humm, K. R. (2020). Abnormal platelet activity in dogs and cats – impact and measurement. Journal of Small Animal Practice, 61(1), 3-18.

Journal Article Type Review
Acceptance Date Oct 28, 2019
Publication Date Jan 9, 2020
Deposit Date Nov 23, 2019
Publicly Available Date Jan 10, 2021
Journal Journal of Small Animal Practice
Print ISSN 0022-4510
Publisher Wiley
Peer Reviewed Peer Reviewed
Volume 61
Issue 1
Pages 3-18
Public URL


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