A C E Draper
Assessing pathological changes within the nucleus ambiguus of horses with Recurrent Laryngeal Neuropathy: an extreme, length-dependent axonopathy
Draper, A C E; Cahalan, S D; Goodwin, D; Perkins, J D M; Piercy, R J
Authors
S D Cahalan
D Goodwin
J D M Perkins
R J Piercy
Abstract
Equine recurrent laryngeal neuropathy (RLN) is a naturally occurring model of length‐dependent axonopathy characterised by asymmetrical degeneration of recurrent laryngeal nerve axons (RLn). Distal RLn degeneration is marked, however it is unclear whether degeneration extends to include cell bodies (consistent with a neuronopathy).
With examiners blinded to RLN severity, brainstem location and side, we examined correlations between RLN severity (assessed using left distal RLn myelinated axon count) and histopathological features (including chromatolysis and glial responses) in the nucleus ambiguus cell bodies, and myelinated axon count of the right distal RLn of 16 horses.
Citation
Draper, A. C. E., Cahalan, S. D., Goodwin, D., Perkins, J. D. M., & Piercy, R. J. (2019). Assessing pathological changes within the nucleus ambiguus of horses with Recurrent Laryngeal Neuropathy: an extreme, length-dependent axonopathy. Muscle & Nerve, https://doi.org/10.1002/mus.26699
Journal Article Type | Article |
---|---|
Acceptance Date | Sep 3, 2019 |
Publication Date | Sep 9, 2019 |
Deposit Date | Sep 11, 2019 |
Publicly Available Date | Sep 15, 2020 |
Journal | MUSCLE & NERVE |
Print ISSN | 0148-639X |
Electronic ISSN | 1097-4598 |
Publisher | Wiley |
Peer Reviewed | Peer Reviewed |
DOI | https://doi.org/10.1002/mus.26699 |
Public URL | https://rvc-repository.worktribe.com/output/1380529 |
Files
12355_Assessing-pathological-changes-within-the-nucleus-ambiguus-of-horses-with-Recurrent-Laryngeal-Neuropathy_Accepted.pdf
(929 Kb)
PDF
You might also like
The cholinergic anti-inflammatory pathway inhibits inflammation without lymphocyte relay
(2023)
Journal Article
Organotopic organization of the porcine mid-cervical vagus nerve
(2023)
Journal Article
Downloadable Citations
About RVC Repository
Administrator e-mail: publicationsrepos@rvc.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2024
Advanced Search