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Signalment risk factors for cutaneous and renal glomerular vasculopathy (Alabama rot) in dogs in the UK

Stevens, K B; O'Neill, D G; Jepson, R E; Holm, L P; Walker, D J; Cardwell, J M


K B Stevens

D G O'Neill

R E Jepson

L P Holm

D J Walker

J M Cardwell


Seasonal outbreaks of cutaneous and renal glomerular vasculopathy (CRGV) have been reported annually in UK dogs since 2012, yet the aetiology of the disease remains unknown. The objectives of this study were to explore whether any breeds had an increased or decreased risk of being diagnosed with CRGV, and to report on age and sex distributions of CRGV cases occurring in the UK. Multivariable logistic regression was used to compare 101 dogs diagnosed with CRGV between November 2012 and May 2017 with a denominator population of 446,453 dogs from the VetCompass database. Two Kennel Club breed groups—hounds (odds ratio (OR) 10.68) and gun dogs (OR 9.69)—had the highest risk of being diagnosed with CRGV compared with terriers, while toy dogs were absent from among CRGV cases. Females were more likely to be diagnosed with CRGV (OR 1.51) as were neutered dogs (OR 3.36). As well as helping veterinarians develop an index of suspicion for the disease, better understanding of the signalment risk factors may assist in the development of causal models for CRGV and help identify the aetiology of the disease.


Stevens, K. B., O'Neill, D. G., Jepson, R. E., Holm, L. P., Walker, D. J., & Cardwell, J. M. (2018). Signalment risk factors for cutaneous and renal glomerular vasculopathy (Alabama rot) in dogs in the UK. Veterinary Record, 183(14), 448.

Journal Article Type Article
Acceptance Date Jul 27, 2018
Publication Date Aug 27, 2018
Deposit Date Aug 31, 2018
Publicly Available Date Sep 4, 2018
Print ISSN 0042-4900
Publisher BMJ Publishing Group
Peer Reviewed Peer Reviewed
Volume 183
Issue 14
Pages 448
Public URL


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