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Feline primary erythrocytosis: a multicentre case series of 18 cats

Darcy, H; Simpson, K; Gajanayake, I; Seth, M; McGrotty, Y; Szladovits, B; Glanemann, B


H Darcy

K Simpson

I Gajanayake

M Seth

Y McGrotty

B Szladovits

B Glanemann


A retrospective multicentre case series of feline primary erythrocytosis (PE) was evaluated. The aim was to gain better understanding of disease presentation and progression to guide management and prognostication. Case records were assessed for evidence of increased packed cell volume (PCV; >48%), sufficient investigation to rule out relative and secondary erythrocytosis, and follow-up data for at least 12 months or until death. Eighteen cats were included in the case series. No significant trends in signalment were noted. Seizures and mentation changes were the most common presenting signs (both n = 10). Median PCV was 70% (median total protein concentration of 76 g/l) with no other consistent haematological changes. Sixteen cats survived to discharge. Phlebotomy was performed initially in 15/16 surviving animals and performed after discharge in 10/16. Hydroxyurea was the most common adjunctive therapy, used in 10/16 cats. Of the 16 patients surviving to discharge, 14 patients were still alive at the conclusion of the study (survival time >17 months post-discharge), with the two non-survivors having lived for 5 years or more after diagnosis. PCV, when stabilised, did not correlate with resolution of clinical signs.


Darcy, H., Simpson, K., Gajanayake, I., Seth, M., McGrotty, Y., Szladovits, B., & Glanemann, B. (2018). Feline primary erythrocytosis: a multicentre case series of 18 cats. Journal of Feline Medicine and Surgery,

Journal Article Type Other
Acceptance Date Nov 27, 2017
Publication Date Jan 24, 2018
Deposit Date Feb 23, 2018
Publicly Available Date Feb 23, 2018
Print ISSN 1098-612X
Publisher Elsevier
Peer Reviewed Peer Reviewed
Public URL


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