H Darcy
Feline primary erythrocytosis: a multicentre case series of 18 cats
Darcy, H; Simpson, K; Gajanayake, I; Seth, M; McGrotty, Y; Szladovits, B; Glanemann, B
Authors
K Simpson
I Gajanayake
M Seth
Y McGrotty
B Szladovits
B Glanemann
Abstract
A retrospective multicentre case series of feline primary erythrocytosis (PE) was evaluated. The aim was to gain better understanding of disease presentation and progression to guide management and prognostication. Case records were assessed for evidence of increased packed cell volume (PCV; >48%), sufficient investigation to rule out relative and secondary erythrocytosis, and follow-up data for at least 12 months or until death. Eighteen cats were included in the case series. No significant trends in signalment were noted. Seizures and mentation changes were the most common presenting signs (both n = 10). Median PCV was 70% (median total protein concentration of 76?g/l) with no other consistent haematological changes. Sixteen cats survived to discharge. Phlebotomy was performed initially in 15/16 surviving animals and performed after discharge in 10/16. Hydroxyurea was the most common adjunctive therapy, used in 10/16 cats. Of the 16 patients surviving to discharge, 14 patients were still alive at the conclusion of the study (survival time >17 months post-discharge), with the two non-survivors having lived for 5 years or more after diagnosis. PCV, when stabilised, did not correlate with resolution of clinical signs.
Citation
Darcy, H., Simpson, K., Gajanayake, I., Seth, M., McGrotty, Y., Szladovits, B., & Glanemann, B. (2018). Feline primary erythrocytosis: a multicentre case series of 18 cats. Journal of Feline Medicine and Surgery, https://doi.org/10.1177/1098612X17750333
Journal Article Type | Other |
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Acceptance Date | Nov 27, 2017 |
Publication Date | Jan 24, 2018 |
Deposit Date | Feb 23, 2018 |
Publicly Available Date | Nov 21, 2020 |
Journal | JOURNAL OF FELINE MEDICINE AND SURGERY |
Print ISSN | 1098-612X |
Publisher | Elsevier |
Peer Reviewed | Peer Reviewed |
DOI | https://doi.org/10.1177/1098612X17750333 |
Public URL | https://rvc-repository.worktribe.com/output/1389090 |
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