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Nanobodies raised against monomeric a-synuclein inhibit fibril-formation and destabilize toxic oligomeric species of a-synuclein

Iljina, M; Hong, L; Horrocks, M H; Ludtmann, M H R; Hughes, C D; Choi, M L; Ruggeri, F S; Guilliams, T; Buell, A K; Gandhi, S; Bryant, C E; Vendruscolo, M; Knowles, T P J; Dobson, C M; De Genst, E; Klenerman, D

Authors

M Iljina

L Hong

M H Horrocks

M H R Ludtmann

C D Hughes

M L Choi

F S Ruggeri

T Guilliams

A K Buell

S Gandhi

C E Bryant

M Vendruscolo

T P J Knowles

C M Dobson

E De Genst

D Klenerman



Citation

Iljina, M., Hong, L., Horrocks, M. H., Ludtmann, M. H. R., Hughes, C. D., Choi, M. L., Ruggeri, F. S., Guilliams, T., Buell, A. K., Gandhi, S., Bryant, C. E., Vendruscolo, M., Knowles, T. P. J., Dobson, C. M., De Genst, E., & Klenerman, D. (2017). Nanobodies raised against monomeric a-synuclein inhibit fibril-formation and destabilize toxic oligomeric species of a-synuclein. BMC Biology, 15(57), https://doi.org/10.1186/s12915-017-0390-6

Journal Article Type Article
Acceptance Date Jun 6, 2017
Publication Date Jul 3, 2017
Deposit Date Jul 24, 2018
Publicly Available Date Jul 24, 2018
Journal BMC Biology
Electronic ISSN 1741-7007
Publisher BioMed Central
Peer Reviewed Peer Reviewed
Volume 15
Issue 57
DOI https://doi.org/10.1186/s12915-017-0390-6
Public URL https://rvc-repository.worktribe.com/output/1391299

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