HIV and schistosomiasis co-infection in African children

Bustinduy, A; King, C; Scott, J; Appleton, S; Sousa-Figueiredo, J C; Betson, M; Stothard, J R

Abstract

HIV/AIDS and schistosomiasis both cause a substantial disease burden in sub-Saharan Africa and the two diseases often overlap in their epidemiological characteristics. Although disease-specific control interventions are continuing, potential synergies in the control efforts for these two diseases have not been investigated. With a focus on children with schistosomiasis, we assess the risk for increased HIV transmission, HIV progression, and impaired response to drugs when given alongside HIV interventions. A new research agenda tailored to children is needed to better understand the interactions of these two diseases and the potential for combined responses.

Citation

Bustinduy, A., King, C., Scott, J., Appleton, S., Sousa-Figueiredo, J. C., Betson, M., & Stothard, J. R. (in press). HIV and schistosomiasis co-infection in African children. https://doi.org/10.1016/S1473-3099%2814%2970001-5

• Journal Article Type: Review
• Acceptance Date: Apr 1, 2014
• Deposit Date: Nov 11, 2014
• Journal: Lancet Infectious Disease
• Peer Reviewed: Peer Reviewed
• Volume: 14
• Issue: 7
• Pages: 640-649
• DOI: https://doi.org/10.1016/S1473-3099%2814%2970001-5
• Public URL: https://rvc-repository.worktribe.com/output/1405756
• Additional Information: Corporate Creators : Cambridge, Case Western Reserve, Liverpool