Sian Marie Frosini
Effect of topical antimicrobial therapy and household cleaning on meticillin-resistant Staphylococcus pseudintermedius carriage in dogs
Frosini, Sian Marie; Bond, Ross; King, Ruth; Feudi, Claudia; Schwarz, Stefan; Loeffler, Anette
MRSP is a multidrug-resistant, zoonotic canine pathogen. This study investigated MRSP carriage and clearance through topical antimicrobial therapy and household cleaning in dogs recovered from MRSP infection.
Dogs were swabbed for MRSP carriage; household contamination was assessed using contact plates. Carrier dogs were allocated randomly to receive topical fusidic acid and chlorhexidine/miconazole treatment combined with owners implementing a household hygiene protocol (H&T) or implementation of hygiene alone (H) over three weeks. Carriage-negative dogs were monitored monthly. Relatedness of isolates over time was investigated by PFGE.
At inclusion, MRSP carriage was confirmed in 31/46 (67.4%) index dogs, 16/24 (66.7%) contact dogs and contamination was found in 18/40 (45%) environments. In dogs completing all cycles, interventions cleared carriage in 5/9 (55.6%) dogs in group H&T and 2/6 (33.3%) in group H. Carriage frequency reduced with topical antimicrobial treatment and hygiene (P
Frosini, S. M., Bond, R., King, R., Feudi, C., Schwarz, S., & Loeffler, A. (2021). Effect of topical antimicrobial therapy and household cleaning on meticillin-resistant Staphylococcus pseudintermedius carriage in dogs. BMJ Open, https://doi.org/10.1002/vetr.937
|Journal Article Type||Article|
|Acceptance Date||Aug 28, 2021|
|Publication Date||Sep 27, 2021|
|Deposit Date||Jan 28, 2021|
|Publicly Available Date||Jul 15, 2022|
|Publisher||BMJ Publishing Group|
|Peer Reviewed||Peer Reviewed|
You might also like
Treating canine pyoderma with topical antibacterial therapy