Position Statement: Minimal criteria for reporting veterinary and animal  medicine research for mesenchymal stromal/stem cells in orthopaedic  applications.

Guest, D J; Dudhia, J; Smith, R K; Roberts, S; Conzemius, M; Innes, J F; Fortier, L; Meeson, R L

doi:10.3389/fvets.2022.817041

Authors

D J Guest

J Dudhia

R K Smith

S Roberts

M Conzemius

J F Innes

L Fortier

R L Meeson

Abstract

Mesenchymal stromal/stem cells (MSCs) are being used in an increasingly broad range of clinical applications in horses, dogs and cats. In this position statement, we aim to provide guidelines to improve reporting research involving the use of MSCs in veterinary clinical settings to drive a more robust approach to this area of research and thus ensure outputs are useful, clinically relevant and informative. We propose that there should be minimal definition criteria for the identity of the cells under investigation and that reporting of inclusion/exclusion clinical criteria and standard outcome measures is essential. We propose that this framework is consistently used as our understanding and application of other technologies to this field develops. Incorporating these guidelines in the planning and publication of research this will drive higher scientific standards and enable better comparison between studies.

Citation

Guest, D. J., Dudhia, J., Smith, R. K., Roberts, S., Conzemius, M., Innes, J. F., …Meeson, R. L. (2022). Position Statement: Minimal criteria for reporting veterinary and animal medicine research for mesenchymal stromal/stem cells in orthopaedic applications. Frontiers in Veterinary Science, https://doi.org/10.3389/fvets.2022.817041

Journal Article Type	Article
Acceptance Date	Feb 8, 2022
Publication Date	Mar 7, 2022
Deposit Date	Nov 9, 2021
Publicly Available Date	Jul 12, 2022
Publisher	Frontiers Media
Peer Reviewed	Peer Reviewed
DOI	https://doi.org/10.3389/fvets.2022.817041
Keywords	Mesenchymal; stem; stromal; cell; orthopaedics; dog; horse