Waterhouse-Friderichsen syndrome in a cat with Klebsiella spp. infection

Cole, LP; Hardas, A; Priestnall, SL; Tinson, EW

Abstract

Objective To describe a case of Waterhouse-Friderichsen syndrome of adrenocortical failure in a cat with Klebsiella spp. infection. Case Summary A 12-year-old male neutered domestic short-haired cat was referred for respiratory failure requiring mechanical ventilation. The cat remained comatose despite successful weaning from the ventilator and developed a Klebsiella pneumoniae pneumonia. On day 4 of hospitalization, the cat acutely deteriorated with profound hypotension, azotemia, and hyperkalemia, which rapidly progressed to cardiac arrest. Necropsy findings revealed massive adrenal hemorrhage and intralesional bacteria, termed Waterhouse-Friderichsen syndrome. Waterhouse-Friderichsen syndrome was suspected to have been the cause of acquired adrenocortical insufficiency and sudden death of the cat. New or Unique Information To the authors' knowledge, this is the first report of sepsis causing Waterhouse-Friderichsen syndrome in a veterinary species.

Citation

Cole, L., Hardas, A., Priestnall, S., & Tinson, E. (2021). Waterhouse-Friderichsen syndrome in a cat with Klebsiella spp. infection. Journal of Veterinary Emergency and Critical Care, 31(4), 531-536. https://doi.org/10.1111/vec.13063

• Journal Article Type: Article
• Acceptance Date: May 4, 2021
• Publication Date: 2021
• Deposit Date: Nov 23, 2021
• Publicly Available Date: Nov 23, 2021
• Journal: Journal of Veterinary Emergency and Critical Care
• Print ISSN: 1479-3261
• Electronic ISSN: 1476-4431
• Publisher: Wiley
• Peer Reviewed: Peer Reviewed
• Volume: 31
• Issue: 4
• Pages: 531-536
• DOI: https://doi.org/10.1111/vec.13063
• Keywords: CORTICOSTEROID INSUFFICIENCY CIRCI; RELATIVE ADRENAL INSUFFICIENCY; CARE MEDICINE SCCM; EUROPEAN-SOCIETY; HEMORRHAGE
• Public URL: https://rvc-repository.worktribe.com/output/1552703