Correlation between magnetic resonance imaging and histological lesions in a case of meningoencephalomyelitis secondary to Neospora caninum infection in a greyhound

Albertini, GM; Stabile, F; Yaffy, D; Suaez-Bonnet, A; Uriarte, A

Abstract

An 11-year-old, male, neutered raw fed greyhound was presented for a 2-week history of progressive non-lateralised, non-painful ambulatory paraparesis, deteriorating acutely to non-ambulatory tetraparesis. Magnetic resonance imaging, cerebrospinal fluid analysis and polymerase chain reaction tests confirmed the diagnosis of meningoencephalomyelitis secondary to Neospora caninum infection. Despite treatment, the patient deteriorated and was euthanased. Postmortem examination revealed diffuse areas of necrotising encephalomyelitis, multifocal non-suppurative encephalomyelitis and areas of necrotising non-suppurative cerebellitis. N. caninum parasitic cysts could also be identified. This is the first case report of correlated histological features and magnetic resonance imaging of meningoencephalomyelitis secondary to N. caninum. This case report was presented as an online poster presentation at the online 33rd ESVN-ECVN symposium.

Citation

Albertini, G., Stabile, F., Yaffy, D., Suaez-Bonnet, A., & Uriarte, A. (2022). Correlation between magnetic resonance imaging and histological lesions in a case of meningoencephalomyelitis secondary to Neospora caninum infection in a greyhound. Vet Record Case Reports, https://doi.org/10.1002/vrc2.440

• Journal Article Type: Article
• Acceptance Date: Jun 7, 2022
• Online Publication Date: Jun 22, 2022
• Publication Date: Nov 7, 2022
• Deposit Date: Jun 3, 2024
• Print ISSN: 2052-6121
• Publisher: BMJ Publishing Group
• Peer Reviewed: Peer Reviewed
• DOI: https://doi.org/10.1002/vrc2.440
• Keywords: CENTRAL-NERVOUS-SYSTEM; NONSUPPURATIVE MENINGOENCEPHALITIS; NECROTIZING CEREBELLITIS; YOUNG GREYHOUNDS; CLINICAL SIGNS; DOGS; DIAGNOSIS