East Coast fever, a neglected tropical disease with an outdated vaccine approach?

Kolakowski, J; Connelley, T; Lukacik, P; Pfuhl, M; Werling, D

Abstract

Since its discovery, bovine theileriosis has caused major socioeconomic losses in sub-Saharan Africa. Acaricide resistance of the intermediate host, paucity of therapeutics, and lack of sufficiently cross-protective vaccines increase the risk of parasite spread due to global warming. Here, we highlight three important areas that require investigation to develop next-generation vaccines.

Citation

Kolakowski, J., Connelley, T., Lukacik, P., Pfuhl, M., & Werling, D. (2022). East Coast fever, a neglected tropical disease with an outdated vaccine approach?. Trends in Parasitology, 38(11), 930-932. https://doi.org/10.1016/j.pt.2022.08.006

• Journal Article Type: Article
• Acceptance Date: Aug 13, 2022
• Online Publication Date: Aug 27, 2022
• Publication Date: 2022
• Deposit Date: Aug 15, 2023
• Publicly Available Date: Aug 15, 2023
• Print ISSN: 1471-4922
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 38
• Issue: 11
• Pages: 930-932
• DOI: https://doi.org/10.1016/j.pt.2022.08.006
• Keywords: T-CELL RESPONSES; THEILERIA-PARVA; ANTIGEN; IMMUNE