DNA methylation networks underlying mammalian traits

Haghani, Amin; Li, Caesar Z.; Robeck, Todd R.; Zhang, Joshua; Lu, Ake T.; Ablaeva, Julia; Acosta-Rodríguez, Victoria A.; Adams, Danielle M.; Alagaili, Abdulaziz N.; Almunia, Javier; Aloysius, Ajoy; Amor, Nabil M.S.; Ardehali, Reza; Arneson, Adriana; Baker, C. Scott; Banks, Gareth; Belov, Katherine; Bennett, Nigel C.; Black, Peter; Blumstein, Daniel T.; Bors, Eleanor K.; Breeze, Charles E.; Brooke, Robert T.; Brown, Janine L.; Carter, Gerald; Caulton, Alex; Cavin, Julie M.; Chakrabarti, Lisa; Chatzistamou, Ioulia; Chavez, Andreas S.; Chen, Hao; Cheng, Kaiyang; Chiavellini, Priscila; Choi, Oi-Wa; Clarke, Shannon; Cook, Joseph A.; Cooper, Lisa N.; Cossette, Marie-Laurence; Day, Joanna; DeYoung, Joseph; Dirocco, Stacy; Dold, Christopher; Dunnum, Jonathan L.; Ehmke, Erin E.; Emmons, Candice K.; Emmrich, Stephan; Erbay, Ebru; Erlacher-Reid, Claire; Faulkes, Chris G.; Fei, Zhe; Ferguson, Steven H.; Finno, Carrie J.; Flower, Jennifer E.; Gaillard, Jean-Michel; Garde, Eva; Gerber, Livia; Gladyshev, Vadim N.; Goya, Rodolfo G.; Grant, Matthew J; Green, Carla B.; Hanson, M. Bradley; Hart, Daniel W.; Haulena, Martin; Herrick, Kelsey; Hogan, Andrew N.; Hogg, Carolyn J.; Hore, Timothy A.; Huang, Taosheng; Izpisua Belmonte, Juan Carlos; Jasinska, Anna J.; Jones, Gareth; Jourdain, Eve; Kashpur, Olga; Katcher, Harold; Katsumata, Etsuko; Kaza, Vimala; Kiaris, Hippokratis; Kobor, Michael S.; Kordowitzki, Pawel; Koski, William R.; Krützen, Michael; Kwon, Soo Bin; Larison, Brenda; Lee, Sang-Goo; Lehmann, Marianne; Lemaître, Jean-François; Levine, Andrew J.; Li, Xinmin; Li, Cun; Lim, Andrea R.; Lin, David T. S.; Lindemann, Dana M.; Liphardt, Schuyler W.; Little, Thomas J.; Macoretta, Nicholas; Maddox, Dewey; Matkin, Craig O.; Mattison, Julie A.; McClure, Matthew; Mergl, June; Meudt, Jennifer J.; Montano, Gisele A.; Mozhui, Khyobeni; Munshi-South, Jason; Murphy, William J.; Naderi, Asieh; Nagy, Martina; Narayan, Pritika; Nathanielsz, Peter W.; Nguyen, Ngoc B.; Niehrs, Christof; Nyamsuren, Batsaikhan; O’Brien, Justine K.; Ginn, Perrie O’Tierney; Odom, Duncan T; Ophir, Alexander G.; Osborn, Steve; Ostrander, Elaine A.; Parsons, Kim M.; Paul, Kimberly C.; Pedersen, Amy B.; Pellegrini, Matteo; Peters, Katharina J.; Petersen, Jessica L.; Pietersen, Darren W.; Pinho, Gabriela M.; Plassais, Jocelyn; Poganik, Jesse R.; Prado, Natalia A.; Reddy, Pradeep; Rey, Benjamin; Ritz, Beate R.; Robbins, Jooke; Rodriguez, Magdalena; Russell, Jennifer; Rydkina, Elena; Sailer, Lindsay L.; Salmon, Adam B.; Sanghavi, Akshay; Schachtschneider, Kyle M.; Schmitt, Dennis; Schmitt, Todd; Schomacher, Lars; Schook, Lawrence B.; Sears, Karen E.; Seifert, Ashley W.; Shafer, Aaron B.A.; Shindyapina, Anastasia V.; Simmons, Melanie; Singh, Kavita; Sinha, Ishani; Slone, Jesse; Snell, Russel G.; Soltanmohammadi, Elham; Spangler, Matthew L.; Spriggs, Maria; Staggs, Lydia; Stedman, Nancy; Steinman, Karen J.; Stewart, Donald T; Sugrue, Victoria J.; Szladovits, Balazs; Takahashi, Joseph S.; Takasugi, Masaki; Teeling, Emma C.; Thompson, Michael J.; Van Bonn, Bill; Vernes, Sonja C.; Villar, Diego; Vinters, Harry V.; Vu, Ha; Wallingford, Mary C.; Wang, Nan; Wilkinson, Gerald S.; Williams, Robert W.; Yan, Qi; Yao, Mingjia; Young, Brent G.; Zhang, Bohan; Zhang, Zhihui; Zhao, Yang; Zhao, Peng; Zhou, Wanding; Zoller, Joseph A.; Ernst, Jason; Seluanov, Andrei; Gorbunova, Vera; Yang, X. William; Raj, Ken; Horvath, Steve

doi:10.1126/science.abq5693

DNA methylation networks underlying mammalian traits

Haghani, Amin; Li, Caesar Z.; Robeck, Todd R.; Zhang, Joshua; Lu, Ake T.; Ablaeva, Julia; Acosta-Rodríguez, Victoria A.; Adams, Danielle M.; Alagaili, Abdulaziz N.; Almunia, Javier; Aloysius, Ajoy; Amor, Nabil M.S.; Ardehali, Reza; Arneson, Adriana; Baker, C. Scott; Banks, Gareth; Belov, Katherine; Bennett, Nigel C.; Black, Peter; Blumstein, Daniel T.; Bors, Eleanor K.; Breeze, Charles E.; Brooke, Robert T.; Brown, Janine L.; Carter, Gerald; Caulton, Alex; Cavin, Julie M.; Chakrabarti, Lisa; Chatzistamou, Ioulia; Chavez, Andreas S.; Chen, Hao; Cheng, Kaiyang; Chiavellini, Priscila; Choi, Oi-Wa; Clarke, Shannon; Cook, Joseph A.; Cooper, Lisa N.; Cossette, Marie-Laurence; Day, Joanna; DeYoung, Joseph; Dirocco, Stacy; Dold, Christopher; Dunnum, Jonathan L.; Ehmke, Erin E.; Emmons, Candice K.; Emmrich, Stephan; Erbay, Ebru; Erlacher-Reid, Claire; Faulkes, Chris G.; Fei, Zhe; Ferguson, Steven H.; Finno, Carrie J.; Flower, Jennifer E.; Gaillard, Jean-Michel; Garde, Eva; Gerber, Livia; Gladys...

Authors

Amin Haghani

Caesar Z. Li

Todd R. Robeck

Joshua Zhang

Ake T. Lu

Julia Ablaeva

Victoria A. Acosta-Rodríguez

Danielle M. Adams

Abdulaziz N. Alagaili

Javier Almunia

Ajoy Aloysius

Nabil M.S. Amor

Reza Ardehali

Adriana Arneson

C. Scott Baker

Gareth Banks

Katherine Belov

Nigel C. Bennett

Peter Black

Daniel T. Blumstein

Eleanor K. Bors

Charles E. Breeze

Robert T. Brooke

Janine L. Brown

Gerald Carter

Alex Caulton

Julie M. Cavin

Lisa Chakrabarti

Ioulia Chatzistamou

Andreas S. Chavez

Hao Chen

Kaiyang Cheng

Priscila Chiavellini

Oi-Wa Choi

Shannon Clarke

Joseph A. Cook

Lisa N. Cooper

Marie-Laurence Cossette

Joanna Day

Joseph DeYoung

Stacy Dirocco

Christopher Dold

Jonathan L. Dunnum

Erin E. Ehmke

Candice K. Emmons

Stephan Emmrich

Ebru Erbay

Claire Erlacher-Reid

Chris G. Faulkes

Zhe Fei

Steven H. Ferguson

Carrie J. Finno

Jennifer E. Flower

Jean-Michel Gaillard

Eva Garde

Livia Gerber

Vadim N. Gladyshev

Rodolfo G. Goya

Matthew J Grant

Carla B. Green

M. Bradley Hanson

Daniel W. Hart

Martin Haulena

Kelsey Herrick

Andrew N. Hogan

Carolyn J. Hogg

Timothy A. Hore

Taosheng Huang

Juan Carlos Izpisua Belmonte

Anna J. Jasinska

Gareth Jones

Eve Jourdain

Olga Kashpur

Harold Katcher

Etsuko Katsumata

Vimala Kaza

Hippokratis Kiaris

Michael S. Kobor

Pawel Kordowitzki

William R. Koski

Michael Krützen

Soo Bin Kwon

Brenda Larison

Sang-Goo Lee

Marianne Lehmann

Jean-François Lemaître

Andrew J. Levine

Xinmin Li

Cun Li

Andrea R. Lim

David T. S. Lin

Dana M. Lindemann

Schuyler W. Liphardt

Thomas J. Little

Nicholas Macoretta

Dewey Maddox

Craig O. Matkin

Julie A. Mattison

Matthew McClure

June Mergl

Jennifer J. Meudt

Gisele A. Montano

Khyobeni Mozhui

Jason Munshi-South

William J. Murphy

Asieh Naderi

Martina Nagy

Pritika Narayan

Peter W. Nathanielsz

Ngoc B. Nguyen

Christof Niehrs

Batsaikhan Nyamsuren

Justine K. O’Brien

Perrie O’Tierney Ginn

Duncan T Odom

Alexander G. Ophir

Steve Osborn

Elaine A. Ostrander

Kim M. Parsons

Kimberly C. Paul

Amy B. Pedersen

Matteo Pellegrini

Katharina J. Peters

Jessica L. Petersen

Darren W. Pietersen

Gabriela M. Pinho

Jocelyn Plassais

Jesse R. Poganik

Natalia A. Prado

Pradeep Reddy

Benjamin Rey

Beate R. Ritz

Jooke Robbins

Magdalena Rodriguez

Jennifer Russell

Elena Rydkina

Lindsay L. Sailer

Adam B. Salmon

Akshay Sanghavi

Kyle M. Schachtschneider

Dennis Schmitt

Todd Schmitt

Lars Schomacher

Lawrence B. Schook

Karen E. Sears

Ashley W. Seifert

Aaron B.A. Shafer

Anastasia V. Shindyapina

Melanie Simmons

Kavita Singh

Ishani Sinha

Jesse Slone

Russel G. Snell

Elham Soltanmohammadi

Matthew L. Spangler

Maria Spriggs

Lydia Staggs

Nancy Stedman

Karen J. Steinman

Donald T Stewart

Victoria J. Sugrue

Balazs Szladovits

Joseph S. Takahashi

Masaki Takasugi

Emma C. Teeling

Michael J. Thompson

Bill Van Bonn

Sonja C. Vernes

Diego Villar

Harry V. Vinters

Ha Vu

Mary C. Wallingford

Nan Wang

Gerald S. Wilkinson

Robert W. Williams

Qi Yan

Mingjia Yao

Brent G. Young

Bohan Zhang

Zhihui Zhang

Yang Zhao

Peng Zhao

Wanding Zhou

Joseph A. Zoller

Jason Ernst

Andrei Seluanov

Vera Gorbunova

X. William Yang

Ken Raj

Steve Horvath

Citation

Haghani, A., Li, C. Z., Robeck, T. R., Zhang, J., Lu, A. T., Ablaeva, J., …Horvath, S. (2023). DNA methylation networks underlying mammalian traits. Science, 381(6658), https://doi.org/10.1126/science.abq5693

Journal Article Type	Article
Acceptance Date	Jun 21, 2023
Publication Date	Aug 11, 2023
Deposit Date	Nov 30, 2023
Publicly Available Date	Dec 5, 2023
Journal	Science
Print ISSN	0036-8075
Electronic ISSN	1095-9203
Publisher	American Association for the Advancement of Science
Peer Reviewed	Peer Reviewed
Volume	381
Issue	6658
DOI	https://doi.org/10.1126/science.abq5693
Keywords	Multidisciplinary
Additional Information	Received: 2022-04-19; Accepted: 2023-06-21; Published: 2023-08-11