LOSS OF FUNCTION ALPHA10BETA1 MICE EXHIBIT REDUCED BONE VOLUME
Journal Article
Collinson, R. S., Bengtsson, T., Lundgren-Akerlund, E., & Pitsillides, A. A. LOSS OF FUNCTION ALPHA10BETA1 MICE EXHIBIT REDUCED BONE VOLUME. Calcified Tissue International, 82(1), S36-S36
All Outputs (192)
A critical evaluation of specific aspects of joint development
Journal Article
Pitsillides, A. A., & Ashhurst, D. E. A critical evaluation of specific aspects of joint development. Developmental Dynamics, 237(9), 2284-2294. https://doi.org/10.1002/dvdy.21654Synovial joint formation has been divided into two phases; the formation of the anlagen of the opposing bones and the interzone and the later formation of the joint cavity. Here we review current theories on the mechanism by which these events are ac... Read More about A critical evaluation of specific aspects of joint development.
IN VIVO LOADING OF MURINE KNEE JOINTS: VALIDATION AS A MODEL FOR THE STUDY OF OA
Journal Article
Poulet, B., Collinson, R., & Pitsillides, A. A. IN VIVO LOADING OF MURINE KNEE JOINTS: VALIDATION AS A MODEL FOR THE STUDY OF OA. International Journal of Experimental Pathology, 89(3), A12-A13
E11 AND RHOA SIGNALLING DURING OSTEOCYTOGENESIS
Journal Article
Prideaux, M., Pitsillides, A. A., Loveridge, N., & Farquharson, C. E11 AND RHOA SIGNALLING DURING OSTEOCYTOGENESIS. Calcified Tissue International, 83(1), 22-22
A NOVEL PROFILE ANALYSIS OF METAPHYSEAL TRABECULAR BONE REVEALS A BIPHASIC DOSE-DEPENDENT RESPONSE TO ADMINISTERED BONE ACTIVE AGENTS
Journal Article
Salmon, P., Pitsillides, A. A., Tivesten, A., Moverare-Skrtic, S., Ohlsson, C., Oste, L., …Van T'Hof, R. A NOVEL PROFILE ANALYSIS OF METAPHYSEAL TRABECULAR BONE REVEALS A BIPHASIC DOSE-DEPENDENT RESPONSE TO ADMINISTERED BONE ACTIVE AGENTS. BONE, 43, S19-S19. https://doi.org/10.1016/j.bone.2008.07.060
Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis
Journal Article
Staines, K. A., Ikpegbu, E., Tornqvist, A. E., Dillon, S., Javaheri, B., Amin, A. K., …Farquharson, C. (in press). Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis. BMC Musculoskeletal Disorders, 20, https://doi.org/10.1186/s12891-019-2731-9Subchondral bone (SCB) thickening is one of the earliest detectable changes in osteoarthritic joints and is considered a potential trigger for subsequent articular cartilage degeneration. In this manuscript, we examine whether disruption to the SCB o... Read More about Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis.
The in vitro behaviour of canine osteoblasts derived from different bone types
Journal Article
Meeson, R. L., Perpétuo, I. P., Parsons, K. J., Orriss, I. R., Shah, M., Pitsillides, A. A., & Doube, M. (in press). The in vitro behaviour of canine osteoblasts derived from different bone types. BMC Veterinary Research, 15(114), https://doi.org/10.1186/s12917-019-1857-1
In Vivo Models of Mechanical Loading
Journal Article
Javaheri, B., Bravenboer, N., Bakker, A. D., Van Der Veen, A., De Souza, R. L., Saxon, L., & Pitsillides, A. A. In Vivo Models of Mechanical Loading. https://doi.org/10.1007/978-1-4939-8997-3_22The skeleton fulfils its mechanical functions through structural organization and material properties of individual bones. It is stated that both cortical and trabecular morphology and mass can be (re)modelled in response to changes in mechanical str... Read More about In Vivo Models of Mechanical Loading.
The chondro-osseous continuum: is it possible to unlock the potential assigned within?
Journal Article
Javaheri, B., Razi, H., Piles, M., De Souza, R., Chang, Y. M., Maric-Mur, I., …Pitsillides, A. A. (in press). The chondro-osseous continuum: is it possible to unlock the potential assigned within?. Frontiers in Bioscience, 6(28), https://doi.org/10.3389/fbioe.2018.00028
EXPLORING AGE-RELATED CHANGES TO THE PUTATIVE TENDON STEM CELL NICHE
Journal Article
Marr, N., Pitsillides, A. A., Dudhia, J., & Thorpe, C. T. (in press). EXPLORING AGE-RELATED CHANGES TO THE PUTATIVE TENDON STEM CELL NICHE. International Journal of Experimental Pathology, 98(6), A9-A9
MURINE CRUCIATE LIGAMENT DEGENERATION AND MARKER EXPRESSION DURING OSTEOARTHRITIS
Journal Article
Ramos, L. D., Bou-Gharios, G., Pitsillides, A. A., Comerford, E. J., & Poulet, B. (in press). MURINE CRUCIATE LIGAMENT DEGENERATION AND MARKER EXPRESSION DURING OSTEOARTHRITIS. International Journal of Experimental Pathology, 98(6), A8-A9
The Mechanics of Skeletal Development
Book Chapter
Novicky, A., Caetano-Silva, S. P., Javaheri, B., & Pitsillides, A. A. The Mechanics of Skeletal Development. . https://doi.org/10.1016/B978-0-12-811467-4.00002-4
Deficiency and Also Transgenic Overexpression of Timp-3 Both Lead to Compromised Bone Mass and Architecture In Vivo
Journal Article
Javaheri, B., Hopkinson, M., Poulet, B., Pollard, A. S., Shefelbine, S. J., Chang, Y. M., …Pitsillides, A. A. (in press). Deficiency and Also Transgenic Overexpression of Timp-3 Both Lead to Compromised Bone Mass and Architecture In Vivo. PLoS ONE, 11(8), e0159657. https://doi.org/10.1371/journal.pone.0159657
The anabolic action of intermittent parathyroid hormone on cortical bone depends partly on its ability to induce nitric oxide-mediated vasorelaxation in BALB/c mice
Journal Article
Gohin, S., Carriero, A., Chenu, C., Pitsillides, A. A., Arnett, T. R., & Marenzana, M. (in press). The anabolic action of intermittent parathyroid hormone on cortical bone depends partly on its ability to induce nitric oxide-mediated vasorelaxation in BALB/c mice. Cell Biochemistry and Function, 34(2), 52-62. https://doi.org/10.1002/cbf.3164
SPONTANEOUS HOME CAGE ACTIVITY IS SENSITIVE TO ANTI-NGF TREATMENT OR CAN BE LINKED TO JOINT STIFFNESS IN DIFFERENT MODELS OF SURGERY-INDUCED OSTEOARTHRITIS
Journal Article
Brenneis, C., Westhof, A., Duschek, J., Chang, Y. M., Pitsillides, A. A., Michaelis, M., …Guehring, H. SPONTANEOUS HOME CAGE ACTIVITY IS SENSITIVE TO ANTI-NGF TREATMENT OR CAN BE LINKED TO JOINT STIFFNESS IN DIFFERENT MODELS OF SURGERY-INDUCED OSTEOARTHRITIS. Osteoarthritis and Cartilage, 24, S498-S499. https://doi.org/10.1016/j.joca.2016.01.913
PENALIZED LINEAR DISCRIMINANT ANALYSIS REVEALS DIVERGENT GAIT PATTERNS IN THREE SURGICALLY-INDUCED OA MODELS
Journal Article
Chang, Y. M., Marsh-Dougerthy, J., Brenneis, C., Kleinschmidt, K., Michaelis, M., Guehring, H., …Pitsillides, A. A. PENALIZED LINEAR DISCRIMINANT ANALYSIS REVEALS DIVERGENT GAIT PATTERNS IN THREE SURGICALLY-INDUCED OA MODELS. Osteoarthritis and Cartilage, 24, S107-S108
CHONDROCYTE-SPECIFIC TIMP3 OVEREXPRESSION DISRUPTS ENDOCHONDRAL GROWTH AND COMPROMISES BONE STRUCTURE AND INTEGRITY: FUNCTIONAL IMPACT OF THE CHONDROCYTE-TO-OSTEOBLAST LINEAGE
Journal Article
Poulet, B., Liu, K., Plumb, D., Vo, P., Shah, M., Staines, K. A., …Carrierro, A. CHONDROCYTE-SPECIFIC TIMP3 OVEREXPRESSION DISRUPTS ENDOCHONDRAL GROWTH AND COMPROMISES BONE STRUCTURE AND INTEGRITY: FUNCTIONAL IMPACT OF THE CHONDROCYTE-TO-OSTEOBLAST LINEAGE. International Journal of Experimental Pathology, 97(6), A7-A7
Non-Invasive Mouse Models of Post-Traumatic Osteoarthritis
Journal Article
Christiansen, B. A., Guilak, F., Lockwood, K. A., Olson, S. A., Pitsillides, A. A., Sandell, L. J., …Haudenschild, D. R. (in press). Non-Invasive Mouse Models of Post-Traumatic Osteoarthritis. Osteoarthritis and Cartilage, 23(10), 1627-1638. https://doi.org/10.1016/j.joca.2015.05.009
MMP and TIMP temporal gene expression during osteocytogenesis
Journal Article
Prideaux, M., Staines, K. A., Jones, E. R., Riley, G. P., Pitsillides, A. A., & Farquharson, C. (in press). MMP and TIMP temporal gene expression during osteocytogenesis. Gene Expression Patterns, 18(1-2), 29-36. https://doi.org/10.1016/j.gep.2015.04.004Osteocytes within bone differentiate from osteoblast precursors which reside in a mineralised extracellular matrix (ECM). Fully differentiated osteocytes are critical for bone development and function but the factors that regulate this differentiatio... Read More about MMP and TIMP temporal gene expression during osteocytogenesis.
A HOLE IN THE HEAD; DEVELOPMENT OF CRANIAL FORAMINA IN THE CHICK EMBRYO
Journal Article
Akbareian, S. E., Fowkes, R. C., Macharia, R., Pitsillides, A. A., & McGonnell, I. M. A HOLE IN THE HEAD; DEVELOPMENT OF CRANIAL FORAMINA IN THE CHICK EMBRYO. International Journal of Experimental Pathology, 96(2), A21-A22