Emulating the EPIC trial using VetCompass primary-care data: causal effects of pimobendan in UK dogs with grade IV/VI heart murmurs
(2025)
Journal Article
Pegram, C., Diaz-Ordaz, K., Brodbelt, D. C., Chang, Y.-M., Boswood, A., Wilshaw, J., Reep, C. A. T., Balling, S., Sahota, J., Church, D. B., & O’Neill, D. G. (2025). Emulating the EPIC trial using VetCompass primary-care data: causal effects of pimobendan in UK dogs with grade IV/VI heart murmurs. PLoS ONE, 20(6), e0325695. https://doi.org/10.1371/journal.pone.0325695
All Outputs (60)
Lasting lockdown love? Problem behaviour and pandemic and non-pandemic related risk factors influencing the owner-dog relationship in a UK cohort of dogs reaching early adulthood (2025)
Journal Article
Merritt, B. L., O’Neill, D. G., Brand, C. L., Belshaw, Z., Dale, F. C., Pegram, C. L., & Packer, R. M. A. (in press). Lasting lockdown love? Problem behaviour and pandemic and non-pandemic related risk factors influencing the owner-dog relationship in a UK cohort of dogs reaching early adulthood. PLoS ONE, 20(2), e0316166. https://doi.org/10.1371/journal.pone.0316166The owner-dog relationship is a critical component of sustained dog ownership. Increased understanding of risk factors for weak owner-dog relationships can identify owner-dog dyads at higher risk of poor welfare outcomes, including dog relinquishment... Read More about Lasting lockdown love? Problem behaviour and pandemic and non-pandemic related risk factors influencing the owner-dog relationship in a UK cohort of dogs reaching early adulthood.
Later-age neutering causes lower risk of early‐onset urinary incontinence than early neutering–a VetCompass target trial emulation study (2024)
Journal Article
O'Neill, D., Diaz-Ordaz, K., Pegram, C., Brodbelt, D. C., Chang, Y.-M., Hall, J. L., & Church, D. B. (2024). Later-age neutering causes lower risk of early‐onset urinary incontinence than early neutering–a VetCompass target trial emulation study. Herpetological Conservation and Biology, 19(7), e0305526. https://doi.org/10.1371/journal.pone.0305526There is growing evidence supporting clinically important associations between age at neutering in bitches and subsequent urinary incontinence (UI), although much of this evidence to date is considered weak. Target trial emulation is an innovative ap... Read More about Later-age neutering causes lower risk of early‐onset urinary incontinence than early neutering–a VetCompass target trial emulation study.
Commonly diagnosed disorders in domestic cats in the UK and their associations with sex and age (2023)
Journal Article
O'Neill, D., Gunn-Moore, D., Sorrell, S., McAuslan, H., Church, D. B., Pegram, C., & Brodbelt, D. C. (2023). Commonly diagnosed disorders in domestic cats in the UK and their associations with sex and age. Journal of Feline Medicine and Surgery, 25(2), https://doi.org/10.1177/1098612x231155016
Risk factors for unilateral cranial cruciate ligament rupture diagnosis and for clinical management in dogs under primary veterinary care in the UK (2023)
Journal Article
Pegram, C., Brodbelt, D., Diaz-Ordaz, K., Chang, Y.-M., Frykfors von Hekkel, A., Church, D., & O'Neill, D. (2023). Risk factors for unilateral cranial cruciate ligament rupture diagnosis and for clinical management in dogs under primary veterinary care in the UK. The Veterinary Journal, https://doi.org/10.1016/j.tvjl.2023.105952This study aimed to evaluate demographic risk factors associated with unilateral cranial cruciate ligament (CCL) rupture diagnosis and to explore demographic and clinical risk factors associated with management of unilateral CCL rupture in dogs under... Read More about Risk factors for unilateral cranial cruciate ligament rupture diagnosis and for clinical management in dogs under primary veterinary care in the UK.
An investigation into an outbreak of pancytopenia in cats in the United Kingdom (2023)
Journal Article
Glanemann, B., Humm, K., Pegram, C., & Chan, D. (2023). An investigation into an outbreak of pancytopenia in cats in the United Kingdom. Journal of Veterinary Internal Medicine, 37, 117-125. https://doi.org/10.1111/jvim.16615Background: In spring 2021 increasing numbers of cats presenting with severe pancytopenia were noted in United Kingdom (UK).
Objective: To describe process and outcome of the investigation performed into the outbreak of pancytopenia in cats.
Anima... Read More about An investigation into an outbreak of pancytopenia in cats in the United Kingdom.
How much is that doodle in the window? Exploring motivations and behaviours of UK owners acquiring designer crossbreed dogs (2019-2020) (2022)
Journal Article
Burnett, E., Brand, C. L., O’Neill, D. G., Pegram, C. L., Belshaw, Z., Stevens, K. B., & Packer, R. M. A. (2022). How much is that doodle in the window? Exploring motivations and behaviours of UK owners acquiring designer crossbreed dogs (2019-2020). Canine Medicine and Genetics, 9(1), https://doi.org/10.1186/s40575-022-00120-xDemand for intentional crosses of purebred dog breeds, often labelled ‘designer crossbreeds’ (e.g., Labrador Retriever X Poodle, the ‘Labradoodle’), has recently increased in the UK. This study aimed to explore this phenomenon by comparing pre-purcha... Read More about How much is that doodle in the window? Exploring motivations and behaviours of UK owners acquiring designer crossbreed dogs (2019-2020).
Skin fold dermatitis in dogs in the UK (2022)
Other
O'Neill, D., Rowe, D., Brodbelt, D., Pegram, C., & Hendricks, A. (2022). Skin fold dermatitis in dogs in the UK
Ironing out the wrinkles and folds in the epidemiology of skin fold dermatitis in dog breeds in the UK (2022)
Journal Article
O'Neill, D., Rowe, D., Brodbelt, D., Pegram, C., & Hendricks, A. (2022). Ironing out the wrinkles and folds in the epidemiology of skin fold dermatitis in dog breeds in the UK. Scientific Reports, 12(1), https://doi.org/10.1038/s41598-022-14483-5Skin fold dermatitis (intertrigo) is an inflammatory process of closely apposing skin surfaces. Extreme conformations towards folded skin in many dog breeds are linked with higher risk. Using anonymised primary-care veterinary data from the VetCompas... Read More about Ironing out the wrinkles and folds in the epidemiology of skin fold dermatitis in dog breeds in the UK.
Demography, disorders and mortality of pet hamsters under primary veterinary care in the United Kingdom in 2016 (2022)
Journal Article
O'Neill, D., Pegram, C., Church, D. B., Brodbelt, D. C., Baldrey, V., & Kim, K. (2022). Demography, disorders and mortality of pet hamsters under primary veterinary care in the United Kingdom in 2016. Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13527
Hamsters in the UK: Health and life expectancy [Infographic] (2022)
Other
O'Neill, D., Kim, K., Brodbelt, D., Church, D., Pegram, C., & Baldrey, V. (2022). Hamsters in the UK: Health and life expectancy [Infographic]
Life tables of annual life expectancy and mortality for companion dogs in the United Kingdom (2022)
Journal Article
Tzu-yun Teng, K., Brodbelt, D., Pegram, C., Church, D., & O’Neill, D. (2022). Life tables of annual life expectancy and mortality for companion dogs in the United Kingdom. Scientific Reports, 12(1), 6415. https://doi.org/10.1038/s41598-022-10341-6A life table is a tabulated expression of life expectancy and mortality-related information at specified ages in a given population. This study applied the VetCompass Programme to generate life tables for the UK dog population both overall and broken... Read More about Life tables of annual life expectancy and mortality for companion dogs in the United Kingdom.
Frequency, breed predispositions and other demographic risk factors for diagnosis of hypothyroidism in dogs under primary veterinary care in the UK (2022)
Journal Article
O'Neill, D., Khoo, J., Brodbelt, D., Church, D., Pegram, C., & Geddes, R. (2022). Frequency, breed predispositions and other demographic risk factors for diagnosis of hypothyroidism in dogs under primary veterinary care in the UK. Canine Medicine and Genetics, 9(1), 11. https://doi.org/10.1186/s40575-022-00123-8
Designer crossbreed dogs: Risks of the booming demand [Infographic] (2022)
Other
Burnett, E., Brand, C., O'Neill, D., Pegram, C., Belshaw, Z., Stevens, K., & Packer, R. (2022). Designer crossbreed dogs: Risks of the booming demand [Infographic]
Health of Pug Dogs in the UK: disorder predispositions and protections (2022)
Journal Article
O'Neill, D., Sahota, J., Brodbelt, D., Church, D., Packer, R., & Pegram, C. (2022). Health of Pug Dogs in the UK: disorder predispositions and protections. Canine Medicine and Genetics, https://doi.org/10.1186/s40575-022-00117-6
Pugs in the UK: Overall Health - Infographic (2022)
Other
O'Neill, D., Sahota, J., Brodbelt, D., Church, D., Packer, R., & Pegram, C. (2022). Pugs in the UK: Overall Health - Infographic
Life expectancy of dogs in the UK [Infographic] (2022)
Other
Teng, K. T.-Y., Brodbelt, D., Pegram, C., Church, D., & O'Neill, D. (2022). Life expectancy of dogs in the UK [Infographic]
Pandemic Puppies: Demographic characteristics, health and early life experiences of puppies acquired during the 2020 phase of the COVID-19 pandemic in the UK (2022)
Journal Article
Brand, C. L., O’Neill, D. G., Belshaw, Z., Pegram, C. L., Stevens, K. B., & Packer, R. M. (2022). Pandemic Puppies: Demographic characteristics, health and early life experiences of puppies acquired during the 2020 phase of the COVID-19 pandemic in the UK. Animals, https://doi.org/10.3390/ani12050629The UK recorded sharp rises in puppy purchasing during the 2020 phase of the COVID-19 pan-demic, with many first-time dog owners purchasing puppies to improve their mental health dur-ing this challenging period. Government restrictions to movement an... Read More about Pandemic Puppies: Demographic characteristics, health and early life experiences of puppies acquired during the 2020 phase of the COVID-19 pandemic in the UK.
Pandemic Puppies Study: Has the pandemic affected the early lives of this unique population? [Infographic] (2022)
Other
Brand, C., O'Neill, D., Belshaw, Z., Pegram, C., Stevens, K., & Packer, R. (2022). Pandemic Puppies Study: Has the pandemic affected the early lives of this unique population? [Infographic]
How much is that doodle in the window? Exploring motivations and behaviours of owners acquiring a designer crossbreed dog in the UK 2019-2020 (2022)
Journal Article
Burnett, E., Brand, C. L., O'Neill, D. G., Pegram, C. L., Belshaw, Z., Stevens, K. B., & Packer, R. M. A. How much is that doodle in the window? Exploring motivations and behaviours of owners acquiring a designer crossbreed dog in the UK 2019-2020. Manuscript submitted for publicationBackground
Demand for intentional crosses of purebred dog breeds, often labelled ‘designer crossbreeds’ (e.g., Labrador Retriever X Poodle, the ‘Labradoodle’), has recently increased in the UK. This study aimed to explore this phenomenon by comparin... Read More about How much is that doodle in the window? Exploring motivations and behaviours of owners acquiring a designer crossbreed dog in the UK 2019-2020.