All Outputs (103)

Expression of Protease-Activated Receptor 1 and 2 and Anti-Tubulogenic Activity of Protease-Activated Receptor 1 in Human Endothelial Colony-Forming Cells (2014)
Journal Article
Fortunato, T. M., Vara, D. S., Wheeler-Jones, C. P. D., & Pula, G. (2014). Expression of Protease-Activated Receptor 1 and 2 and Anti-Tubulogenic Activity of Protease-Activated Receptor 1 in Human Endothelial Colony-Forming Cells. PLoS ONE, 9(10), https://doi.org/10.1371/journal.pone.0109375

Endothelial colony-forming cells (ECFCs) are obtained from the culture of human peripheral blood mononuclear cell (hPBMNC) fractions and are characterised by high proliferative and pro-vasculogenic potential, which makes them of great interest for ce... Read More about Expression of Protease-Activated Receptor 1 and 2 and Anti-Tubulogenic Activity of Protease-Activated Receptor 1 in Human Endothelial Colony-Forming Cells.

High-fat meals rich in EPA plus DHA compared with DHA only have differential effects on postprandial lipemia and plasma 8-isoprostane F-2 alpha concentrations relative to a control high-oleic acid meal: a randomized controlled trial (2014)
Journal Article
Purcell, R., Latham, S. H., Botham, K. M., Hall, W. L., & Wheeler-Jones, C. P. D. (2014). High-fat meals rich in EPA plus DHA compared with DHA only have differential effects on postprandial lipemia and plasma 8-isoprostane F-2 alpha concentrations relative to a control high-oleic acid meal: a randomized controlled trial. American Journal of Clinical Nutrition, 100(4), 1019-1028. https://doi.org/10.3945/ajcn.114.091223

Palmitoleic acid prevents palmitic acid-induced macrophage activation and consequent p38 MAPK-mediated-skeletal muscle insulin resistance (2014)
Journal Article
Talbot, N. A., Wheeler-Jones, C. P. D., & Cleasby, M. E. (2014). Palmitoleic acid prevents palmitic acid-induced macrophage activation and consequent p38 MAPK-mediated-skeletal muscle insulin resistance. Molecular and Cellular Endocrinology, 393(1-2), 129-142. https://doi.org/10.1016/j.mce.2014.06.010

Obesity and saturated fatty acid (SFA) treatment are both associated with skeletal muscle insulin resistance (IR) and increased macrophage infiltration. However, the relative effects of SFA and unsaturated fatty acid (UFA)-activated macrophages on mu... Read More about Palmitoleic acid prevents palmitic acid-induced macrophage activation and consequent p38 MAPK-mediated-skeletal muscle insulin resistance.

Homologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropes (2014)
Journal Article
Thompson, I. R., Mirczuk, S. M., Smith, L., Lessey, A. J., Simbi, B., Sunters, A., …Fowkes, R. C. (2014). Homologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropes. Cell and Tissue Research, 355(2), 425-36. https://doi.org/10.1007/s00441-013-1763-y

The guanylyl cyclases, GC-A and GC-B, are selective receptors for atrial and C-type natriuretic peptides (ANP and CNP, respectively). In the anterior pituitary, CNP and GC-B are major regulators of cGMP production in gonadotropes and yet mouse models... Read More about Homologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropes.

Inhibition of macrophage inflammatory cytokine secretion by chylomicron remnants is dependent on their uptake by the low density lipoprotein receptor
Journal Article
Graham, V. S., Di Maggio, P., Armengol, S., Lawson, C., Wheeler-Jones, C. P. D., & Botham, K. M. Inhibition of macrophage inflammatory cytokine secretion by chylomicron remnants is dependent on their uptake by the low density lipoprotein receptor. https://doi.org/10.1016/j.bbalip.2010.11.008

Celecoxib activates PI-3K/Akt and mitochondrial redox signaling to enhance heme oxygenase-1-mediated anti-inflammatory activity in vascular endothelium
Journal Article
Hamdulay, S. S., Wang, B. F., Birdsey, G. M., Ali, F., Dumont, O., Evans, P. C., …Mason, J. C. Celecoxib activates PI-3K/Akt and mitochondrial redox signaling to enhance heme oxygenase-1-mediated anti-inflammatory activity in vascular endothelium. Free Radical Biology and Medicine, 48(8), 1013-1023. https://doi.org/10.1016/j.freeradbiomed.2010.01.017

SUPPRESSION OF NUCLEAR FACTOR-kappaB ACTIVITY IN MACROPHAGES BY CHYLOMICRON REMNANTS: MODULATION BY THE FATTY ACID COMPOSITION OF THE PARTICLES
Journal Article
De Pascale, C., Graham, V. S., Fowkes, R. C., Wheeler-Jones, C. P. D., & Botham, K. M. SUPPRESSION OF NUCLEAR FACTOR-kappaB ACTIVITY IN MACROPHAGES BY CHYLOMICRON REMNANTS: MODULATION BY THE FATTY ACID COMPOSITION OF THE PARTICLES

INFLUENCE OF LIPID CONTENT AND OXIDATION STATE OF CHYLOMICRON REMNANTS ON ENDOTHELIAL CELL SIGNALLING AND FUNCTION
Journal Article
Dalla-Riva, J., Garonna, E., Elliott, J., Botham, K. M., & Wheeler-Jones, C. P. D. INFLUENCE OF LIPID CONTENT AND OXIDATION STATE OF CHYLOMICRON REMNANTS ON ENDOTHELIAL CELL SIGNALLING AND FUNCTION. https://doi.org/10.1016/j.atherosclerosissup.2010.04.039

Endothelial cells as targets for chylomicron remnants
Journal Article
Dalla-Riva, J., Garonna, E., Elliott, J., Botham, K. M., & Wheeler-Jones, C. P. D. Endothelial cells as targets for chylomicron remnants. https://doi.org/10.1016/j.atherosclerosissup.2010.04.001

The expression of angiogenic growth factors and their receptors in ovarian follicles throughout the estrous cycle in the ewe
Journal Article
Chowdhury, M. W. H., Scaramuzzi, R. J., Wheeler-Jones, C. P. D., & Khalid, M. The expression of angiogenic growth factors and their receptors in ovarian follicles throughout the estrous cycle in the ewe. Theriogenology, 73(7), 856-872. https://doi.org/10.1016/j.theriogenology.2009.10.011

Conventional myosins – unconventional functions.
Journal Article
Chantler, P. D., Wylie, S. R., Wheeler-Jones, C. P. D., & McGonnell, I. M. Conventional myosins – unconventional functions. Biophysical Reviews, 2(2), 67-82. https://doi.org/10.1007/s12551-010-0030-7

DOWN-REGULATION OF MACROPHAGE CYTOKINE SECRETION BY CHYLOMICRON REMNANTS: ROLE OF THE LDL RECEPTOR
Journal Article
Botham, K. M., Graham, V. S., Lawson, C., & Wheeler-Jones, C. P. D. DOWN-REGULATION OF MACROPHAGE CYTOKINE SECRETION BY CHYLOMICRON REMNANTS: ROLE OF THE LDL RECEPTOR. https://doi.org/10.1016/j.atherosclerosissup.2010.04.017

ENDOTHELIN-1 RELEASE FROM HUMAN EMBRYONIC STEM CELL DERIVED-ENDOTHELIAL CELLS (HESC-EC): COMPARISONS WITH HUMAN ENDOTHELIAL CELLS
Journal Article
Reed, D. M., Foldes, G., Gatheral, T., Badiger, R. V., Wheeler-Jones, C. P. D., Ali, N. N., …Mitchell, J. A. ENDOTHELIN-1 RELEASE FROM HUMAN EMBRYONIC STEM CELL DERIVED-ENDOTHELIAL CELLS (HESC-EC): COMPARISONS WITH HUMAN ENDOTHELIAL CELLS. Inflammation Research, 60(1), 224-224

TLR3 AND INTERFERON FUNCTION IN HUMAN EMBRYONIC STEM CELL-DERIVED ENDOTHELIAL CELLS (HESC-EC): RELEVANCE TO VIRAL IMMUNITY
Journal Article
Reed, D. M., Foldes, G., Badiger, R. V., Ali, N. N., Wheeler-Jones, C. P. D., Paul-Clark, M. J., …Mitchell, J. A. TLR3 AND INTERFERON FUNCTION IN HUMAN EMBRYONIC STEM CELL-DERIVED ENDOTHELIAL CELLS (HESC-EC): RELEVANCE TO VIRAL IMMUNITY. Heart, 97(20), 12-12. https://doi.org/10.1136/heartjnl-2011-300920b.33

A NATURALLY OCCURRING MODEL OF LIVER REGENERATION? CHANGES IN MRNA EXPRESSION OF MARKERS OF HEPATIC REGENERATION IN LIVER TISSUE FROM DOGS WITH CONGENITAL PORTOSYSTEMIC SHUNTS FOLLOWING PARTIAL ATTENUATION
Journal Article
Tivers, M. S., Lipscomb, V. J., Smith, K. C., Wheeler-Jones, C. P. D., & House, A. K. A NATURALLY OCCURRING MODEL OF LIVER REGENERATION? CHANGES IN MRNA EXPRESSION OF MARKERS OF HEPATIC REGENERATION IN LIVER TISSUE FROM DOGS WITH CONGENITAL PORTOSYSTEMIC SHUNTS FOLLOWING PARTIAL ATTENUATION. Gut, 61, A127-A127. https://doi.org/10.1136/gutjnl-2012-302514b.133

Endoglin (CD105) is not a specific selection marker for endothelial cells in human islets of Langerhans
Journal Article
Wheeler-Jones, C. P. D., Clarkin, C. E., Farrar, C. E., Dhadda, P., Chagastelles, P., Nardi, N., & Jones, P. M. Endoglin (CD105) is not a specific selection marker for endothelial cells in human islets of Langerhans. Diabetologia, 56(1), 222-224. https://doi.org/10.1007/s00125-012-2763-2

Triacylglycerol-rich lipoproteins derived from healthy donors fed different olive oils modulate cytokine secretion and cyclooxygenase-2 expression in macrophages: the potential role of oleanolic acid
Journal Article
Graham, V. S., Lawson, C., Wheeler-Jones, C. P. D., Perona, J. S., Ruiz-Gutierrez, V., & Botham, K. M. Triacylglycerol-rich lipoproteins derived from healthy donors fed different olive oils modulate cytokine secretion and cyclooxygenase-2 expression in macrophages: the potential role of oleanolic acid. European Journal of Nutrition, 51(3), 301-309. https://doi.org/10.1007/s00394-011-0215-2

Expression of guanylyl cyclase-B (GC-B/NPR2) receptors in normal human fetal pituitaries and human pituitary adenomas implicates a regulatory role for C-type natriuretic peptide
Journal Article
Thompson, I. R., Chand, A. N., King, P. J., Ansorge, O., Karavitaki, N., Jones, C. A., …Fowkes, R. C. Expression of guanylyl cyclase-B (GC-B/NPR2) receptors in normal human fetal pituitaries and human pituitary adenomas implicates a regulatory role for C-type natriuretic peptide. Endocrine-Related Cancer, 19(4), 497-508. https://doi.org/10.1530/ERC-12-0129

Vascular Endothelial Growth Factor (VEGF) and VEGF Receptor Expression in Biopsy Samples of Liver from Dogs with Congenital Portosystemic Shunts
Journal Article
Tivers, M. S., Lipscomb, V. J., Scase, T. J., Priestnall, S. L., House, A. K., Gates, H., …Smith, K. C. Vascular Endothelial Growth Factor (VEGF) and VEGF Receptor Expression in Biopsy Samples of Liver from Dogs with Congenital Portosystemic Shunts. Journal of Comparative Pathology, 147(1), 55-61. https://doi.org/10.1016/j.jcpa.2011.09.001

The effect of estradiol on COX-2, EP2, and EP4 mRNA expression and the extracellular matrix in the cervix of the hypogonadotrophic, ovariectomized ewe
Journal Article
Kershaw-Young, C. M., Scaramuzzi, R. J., McGowan, M. R., Pitsillides, A. A., Wheeler-Jones, C. P. D., & Khalid, M. The effect of estradiol on COX-2, EP2, and EP4 mRNA expression and the extracellular matrix in the cervix of the hypogonadotrophic, ovariectomized ewe. Theriogenology, 73(5), 620-628. https://doi.org/10.1016/j.theriogenology.2009.10.018