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All Outputs (266)

Assessment of glucocorticoid and antibiotic exposure as risk factors for diabetes mellitus in selected dog breeds attending UK primary-care clinics (2023)
Journal Article
Davison, L., O'Neill, D., Brodbelt, D., Church, D., & Heeley, A. (in press). Assessment of glucocorticoid and antibiotic exposure as risk factors for diabetes mellitus in selected dog breeds attending UK primary-care clinics. Veterinary Record, https://doi.org/10.1002/vetr.2785

Background: Diabetes mellitus (DM) is an important endocrine disorder in dogs resulting from interactions between both genetic (non-environmental) and environmental factors. This study aimed to explore prior exposure to glucocorticoid or antibiotic t... Read More about Assessment of glucocorticoid and antibiotic exposure as risk factors for diabetes mellitus in selected dog breeds attending UK primary-care clinics.

Associations Between Dog Breed and Clinical Features of Mammary Epithelial Neoplasia in Bitches: an Epidemiological Study of Submissions to a Single Diagnostic Pathology Centre Between 2008–2021 (2023)
Journal Article
Edmunds, G., Beck, S., Kale, K. U., Spasic, I., O’Neill, D., Brodbelt, D., & Smalley, M. J. (2023). Associations Between Dog Breed and Clinical Features of Mammary Epithelial Neoplasia in Bitches: an Epidemiological Study of Submissions to a Single Diagnostic Pathology Centre Between 2008–2021. Journal of Mammary Gland Biology and Neoplasia, 28(1), https://doi.org/10.1007/s10911-023-09531-3

Risk factors for upper urinary tract uroliths and ureteral obstruction in cats under referral veterinary care in the United Kingdom (2023)
Journal Article
Geddes, R. F., Davison, L. J., Elliott, J., Syme, H. M., & O'Neill, D. G. (2023). Risk factors for upper urinary tract uroliths and ureteral obstruction in cats under referral veterinary care in the United Kingdom. Journal of Veterinary Internal Medicine, 37(2), 567-577. https://doi.org/10.1111/jvim.16659

Background
Cats presenting with upper urinary tract uroliths (UUTUs) and ureteral obstruction (“obstructive UUTU”) are typically younger than cats with idiopathic CKD that often have incidental nephroliths.

Hypothesis
Cats with upper urinary tra... Read More about Risk factors for upper urinary tract uroliths and ureteral obstruction in cats under referral veterinary care in the United Kingdom.

Risk factors for unilateral cranial cruciate ligament rupture diagnosis and for clinical management in dogs under primary veterinary care in the UK (2023)
Journal Article
Pegram, C., Brodbelt, D., Diaz-Ordaz, K., Chang, Y.-M., Frykfors von Hekkel, A., Church, D., & O'Neill, D. (2023). Risk factors for unilateral cranial cruciate ligament rupture diagnosis and for clinical management in dogs under primary veterinary care in the UK. The Veterinary Journal, https://doi.org/10.1016/j.tvjl.2023.105952

This study aimed to evaluate demographic risk factors associated with unilateral cranial cruciate ligament (CCL) rupture diagnosis and to explore demographic and clinical risk factors associated with management of unilateral CCL rupture in dogs under... Read More about Risk factors for unilateral cranial cruciate ligament rupture diagnosis and for clinical management in dogs under primary veterinary care in the UK.

Ionized hypercalcemia in 238 cats from a referral hospital population (2009‐2019) (2023)
Journal Article
Broughton, S. E., O'Neill, D. G., Syme, H. M., & Geddes, R. F. (in press). Ionized hypercalcemia in 238 cats from a referral hospital population (2009‐2019). Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16627

Background
Ionized calcium concentration ([iCa]) is more sensitive for detecting calcium disturbances than serum total calcium concentration but literature on ionized hypercalcemia in cats is limited. Urolithiasis is a possible adverse consequence o... Read More about Ionized hypercalcemia in 238 cats from a referral hospital population (2009‐2019).

Applying clinical audit for quality improvement in canine dystocia cases seen at a UK primary-care emergency practice (2023)
Journal Article
O'Neill, D., Leicester, L., Reid, A., Marshall, R., & Gilbert, S. (2023). Applying clinical audit for quality improvement in canine dystocia cases seen at a UK primary-care emergency practice. Veterinary Record, https://doi.org/10.1002/vetr.2485

Background: The paucity of published veterinary clinical audits suggests that
clinical audit is an under-used tool for quality improvement (QI) in the veterinary
profession. Therefore, a continuous QI process was designed and
implemented at a UK m... Read More about Applying clinical audit for quality improvement in canine dystocia cases seen at a UK primary-care emergency practice.

How much is that doodle in the window? Exploring motivations and behaviours of UK owners acquiring designer crossbreed dogs (2019-2020) (2022)
Journal Article
Burnett, E., Brand, C. L., O’Neill, D. G., Pegram, C. L., Belshaw, Z., Stevens, K. B., & Packer, R. M. A. (2022). How much is that doodle in the window? Exploring motivations and behaviours of UK owners acquiring designer crossbreed dogs (2019-2020). Canine Medicine and Genetics, 9(1), https://doi.org/10.1186/s40575-022-00120-x

Demand for intentional crosses of purebred dog breeds, often labelled ‘designer crossbreeds’ (e.g., Labrador Retriever X Poodle, the ‘Labradoodle’), has recently increased in the UK. This study aimed to explore this phenomenon by comparing pre-purcha... Read More about How much is that doodle in the window? Exploring motivations and behaviours of UK owners acquiring designer crossbreed dogs (2019-2020).

Leptospirosis vaccination in dogs attending UK primary care practices: vaccine uptake and factors associated with administration (2022)
Journal Article
Taylor, C., O'Neill, D., Catchpole, B., & Brodbelt, D. (2022). Leptospirosis vaccination in dogs attending UK primary care practices: vaccine uptake and factors associated with administration. BMC Veterinary Research, 18(285), https://doi.org/10.1186/s12917-022-03382-6

Background
Leptospirosis is a zoonotic disease that is found globally and affects most mammalian species. Vaccination of dogs against leptospirosis is an important approach to preventing clinical disease, or reducing disease severity, as well as red... Read More about Leptospirosis vaccination in dogs attending UK primary care practices: vaccine uptake and factors associated with administration.

Ironing out the wrinkles and folds in the epidemiology of skin fold dermatitis in dog breeds in the UK (2022)
Journal Article
O'Neill, D., Rowe, D., Brodbelt, D., Pegram, C., & Hendricks, A. (2022). Ironing out the wrinkles and folds in the epidemiology of skin fold dermatitis in dog breeds in the UK. Scientific Reports, 12(1), https://doi.org/10.1038/s41598-022-14483-5

Skin fold dermatitis (intertrigo) is an inflammatory process of closely apposing skin surfaces. Extreme conformations towards folded skin in many dog breeds are linked with higher risk. Using anonymised primary-care veterinary data from the VetCompas... Read More about Ironing out the wrinkles and folds in the epidemiology of skin fold dermatitis in dog breeds in the UK.

English Bulldogs in the UK: a VetCompass study of their disorder predispositions and protections (2022)
Journal Article
O’Neill, D. G., Skipper, A., Packer, R. M. A., Lacey, C., Church, D. B., Brodbelt, D. C., & Pegram, C. (2022). English Bulldogs in the UK: a VetCompass study of their disorder predispositions and protections. Canine Medicine and Genetics, 9(1), https://doi.org/10.1186/s40575-022-00118-5

Background
The English Bulldog has risen sharply in popularity over the past decade but its distinctive and extreme conformation is linked to several serious health conditions. Using multivariable analysis of anonymised veterinary clinical data from... Read More about English Bulldogs in the UK: a VetCompass study of their disorder predispositions and protections.

Life tables of annual life expectancy and mortality for companion dogs in the United Kingdom (2022)
Journal Article
Tzu-yun Teng, K., Brodbelt, D., Pegram, C., Church, D., & O’Neill, D. (2022). Life tables of annual life expectancy and mortality for companion dogs in the United Kingdom. Scientific Reports, 12(1), 6415. https://doi.org/10.1038/s41598-022-10341-6

A life table is a tabulated expression of life expectancy and mortality-related information at specified ages in a given population. This study applied the VetCompass Programme to generate life tables for the UK dog population both overall and broken... Read More about Life tables of annual life expectancy and mortality for companion dogs in the United Kingdom.