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All Outputs (280)

Conformational eyelid disorders in dogs under primary veterinary care in the UK - Epidemiology and clinical management (2025)
Journal Article
O'Neill, D., Mustikka, M. P., Brodbelt, D. C., Church, D. B., & Vaattovaara, V. (2025). Conformational eyelid disorders in dogs under primary veterinary care in the UK - Epidemiology and clinical management. Herpetological Conservation and Biology, 20(6), e0326526. https://doi.org/10.1371/journal.pone.0326526

Introduction Natural eyelid conformation is essential for normal function and health of the ocular surface. However, many modern dog types are deliberately bred for abnormal eyelid conformation associated with severe health and welfare issues. This s... Read More about Conformational eyelid disorders in dogs under primary veterinary care in the UK - Epidemiology and clinical management.

Emulating the EPIC trial using VetCompass primary-care data: causal effects of pimobendan in UK dogs with grade IV/VI heart murmurs (2025)
Journal Article
Pegram, C., Diaz-Ordaz, K., Brodbelt, D. C., Chang, Y.-M., Boswood, A., Wilshaw, J., Reep, C. A. T., Balling, S., Sahota, J., Church, D. B., & O’Neill, D. G. (2025). Emulating the EPIC trial using VetCompass primary-care data: causal effects of pimobendan in UK dogs with grade IV/VI heart murmurs. PLoS ONE, 20(6), e0325695. https://doi.org/10.1371/journal.pone.0325695

Epidemiology and clinical management of acute diarrhoea in dogs under primary veterinary care in the UK (2025)
Journal Article
O'Neill, D., Prisk, L. J., Brodbelt, D. C., Church, D. B., & Allerton, F. (2025). Epidemiology and clinical management of acute diarrhoea in dogs under primary veterinary care in the UK. PLoS ONE, 20(6), e0324203. https://doi.org/10.1371/journal.pone.0324203

Background
Acute diarrhoea is a common canine veterinary presentation in the UK. This study
aimed to report the incidence, demographic risk factors and clinical management for
acute diarrhoea diagnosed under primary veterinary care in the UK in 20... Read More about Epidemiology and clinical management of acute diarrhoea in dogs under primary veterinary care in the UK.

Beagles kept as companion animals in the UK – demography, disorders and mortality (2025)
Journal Article
O'Neill, D., Schiksnis, M. R., Brodbelt, D. C., Church, D. B., Goldberg, S., & Engdahl, K. S. (2025). Beagles kept as companion animals in the UK – demography, disorders and mortality. Companion Animal Health and Genetics, 12(1), https://doi.org/10.1186/s40575-024-00140-9

Background Beagles are a popular companion animal dog breed and are generally stated to be a healthy breed.
This VetCompass study aimed to report the demography, common disorders and mortality of Beagles under primary
veterinary care in the UK. Ano... Read More about Beagles kept as companion animals in the UK – demography, disorders and mortality.

Conformation-associated health in pet rabbits in the UK: A VetCompass cohort study (2024)
Journal Article
O'Neill, D., Williams, A., Brodbelt, D. C., Church, D. B., & Hedley, J. (2024). Conformation-associated health in pet rabbits in the UK: A VetCompass cohort study. Herpetological Conservation and Biology, https://doi.org/10.1002/vetr.4396

Abstract Background Domestic rabbit breeds vary substantially from the wild rabbit body type. However, little is known about how the conformation of pet rabbits influences their health. Methods Data were extracted from VetCompass anonymised clinical... Read More about Conformation-associated health in pet rabbits in the UK: A VetCompass cohort study.

Later-age neutering causes lower risk of early‐onset urinary incontinence than early neutering–a VetCompass target trial emulation study (2024)
Journal Article
O'Neill, D., Diaz-Ordaz, K., Pegram, C., Brodbelt, D. C., Chang, Y.-M., Hall, J. L., & Church, D. B. (2024). Later-age neutering causes lower risk of early‐onset urinary incontinence than early neutering–a VetCompass target trial emulation study. Herpetological Conservation and Biology, 19(7), e0305526. https://doi.org/10.1371/journal.pone.0305526

There is growing evidence supporting clinically important associations between age at neutering in bitches and subsequent urinary incontinence (UI), although much of this evidence to date is considered weak. Target trial emulation is an innovative ap... Read More about Later-age neutering causes lower risk of early‐onset urinary incontinence than early neutering–a VetCompass target trial emulation study.

Life tables of annual life expectancy and risk factors for mortality in cats in the UK (2024)
Journal Article
O'Neill, D., Kendy Tzu-yun, T., Dave C, B., & David B, C. (2024). Life tables of annual life expectancy and risk factors for mortality in cats in the UK. Herpetological Conservation and Biology, 26(5), 1098612X241234556. https://doi.org/10.1177/1098612x241234556

ObjectivesThe aims of the present study were to generate the first life tables for the UK companion cat population overall as well as broken down by sex and breed status, and to quantify associations between mortality and traits such as sex, neuter s... Read More about Life tables of annual life expectancy and risk factors for mortality in cats in the UK.

The epidemiology of tick infestation in dog breeds in the UK (2024)
Journal Article
O'Neill, D., Komutrattananon, R., Hartley, A., Brodbelt, D., & Church, D. (2024). The epidemiology of tick infestation in dog breeds in the UK. Herpetological Conservation and Biology, https://doi.org/10.1111/jsap.13727

Objectives: The purpose of this study is to report the prevalence and risk factors for tick infestation in
dogs in the UK based on anonymised electronic patient records.
Materials and Methods: Clinical records of dogs under veterinary care in 2016... Read More about The epidemiology of tick infestation in dog breeds in the UK.

Target Trial Emulation: Does surgical versus non-surgical management of cranial cruciate ligament rupture in dogs cause different outcomes? (2024)
Journal Article
Pegram, C., Diaz-Ordaz, K., Brodbelt, D. C., Chang, Y.-M., von Hekkel, A. F., Wu, C.-H., Church, D. B., & O’Neill, D. G. (2024). Target Trial Emulation: Does surgical versus non-surgical management of cranial cruciate ligament rupture in dogs cause different outcomes?. Preventive Veterinary Medicine, 106165. https://doi.org/10.1016/j.prevetmed.2024.106165

Target trial emulation applies design principles from randomised controlled trials to the analysis of observational data for causal inference and is increasingly used within human epidemiology. Using anonymised veterinary clinical data from the VetCo... Read More about Target Trial Emulation: Does surgical versus non-surgical management of cranial cruciate ligament rupture in dogs cause different outcomes?.

Feline Comorbidities: Hypersomatotropism-induced diabetes in cats (2024)
Journal Article
Scudder, C., & Church, D. (2024). Feline Comorbidities: Hypersomatotropism-induced diabetes in cats. Journal of Feline Medicine and Surgery, 26(2), https://doi.org/10.1177/1098612x241226690

Practical relevance:
Diabetes mellitus is the second-most common feline endocrinopathy, affecting an estimated 1/200 cats. While the underlying causes vary, around 15-25% of cats with diabetes mellitus develop the condition secondarily to progressiv... Read More about Feline Comorbidities: Hypersomatotropism-induced diabetes in cats.

Demography, common disorders and mortality of Shih Tzu dogs under primary veterinary care in the UK (2024)
Journal Article
O'Neill, D., Brodbelt, D., Church, D., & Dale, F. (2024). Demography, common disorders and mortality of Shih Tzu dogs under primary veterinary care in the UK. Herpetological Conservation and Biology, 11(1), 2. https://doi.org/10.1186/s40575-023-00135-y

Background Shih Tzus are a popular dog breed in the UK although there is relatively little reported information
on their health. This study aimed to characterise the demography, common disorders and mortality of Shih Tzus
under primary veterinary c... Read More about Demography, common disorders and mortality of Shih Tzu dogs under primary veterinary care in the UK.

Epidemiology of mammary tumours in bitches under veterinary care in the UK in 2016 (2023)
Journal Article
Varney, D., O'Neill, D., O'Neill, M., Church, D., Stell, A., Beck, S., Smalley, M. J., & Brodbelt, D. (2023). Epidemiology of mammary tumours in bitches under veterinary care in the UK in 2016. Veterinary Record, https://doi.org/10.1002/vetr.3054

BackgroundThere is limited information on the epidemiology of canine mammary tumours. This study aimed to estimate the incidence and risk factors for mammary tumours in UK bitches. MethodsA nested case-control study was conducted within VetCompass to... Read More about Epidemiology of mammary tumours in bitches under veterinary care in the UK in 2016.

High-frequency ultrasound biomicroscopy findings of the skin of dogs with atopic dermatitis (2023)
Journal Article
Mantis, P., Sofou, E., Aleksandrova, S., Badulescu, E., Church, D., Lloyd, D., Koutsouvelis, P., Mpairamoglou, S., Chatzis, M., & Saridomichelakis, M. (2023). High-frequency ultrasound biomicroscopy findings of the skin of dogs with atopic dermatitis. Veterinary Dermatology, https://doi.org/10.1111/vde.13169

Background: The high-frequency ultrasonographic appearance of skin of dogs with atopic dermatitis (cAD) has not been described.Objectives: To compare high-frequency ultrasonographic findings among lesional, macroscopically nonlesional skin of dogs wi... Read More about High-frequency ultrasound biomicroscopy findings of the skin of dogs with atopic dermatitis.

Assessment of glucocorticoid and antibiotic exposure as risk factors for diabetes mellitus in selected dog breeds attending UK primary-care clinics (2023)
Journal Article
Davison, L., O'Neill, D., Brodbelt, D., Church, D., & Heeley, A. (in press). Assessment of glucocorticoid and antibiotic exposure as risk factors for diabetes mellitus in selected dog breeds attending UK primary-care clinics. Veterinary Record, https://doi.org/10.1002/vetr.2785

Background: Diabetes mellitus (DM) is an important endocrine disorder in dogs resulting from interactions between both genetic (non-environmental) and environmental factors. This study aimed to explore prior exposure to glucocorticoid or antibiotic t... Read More about Assessment of glucocorticoid and antibiotic exposure as risk factors for diabetes mellitus in selected dog breeds attending UK primary-care clinics.