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G-Anchor: a novel approach for whole-genome comparative mapping utilising evolutionary conserved DNA sequences
Journal Article
Lenis, V. E., Swain, M., & Larkin, D. M. (in press). G-Anchor: a novel approach for whole-genome comparative mapping utilising evolutionary conserved DNA sequences. GigaScience, 7(5), https://doi.org/10.1093/gigascience/giy017

Here we introduce G-Anchor, a new, fast, and efficient pipeline that uses a strictly limited but highly effective set of local sequence alignments to anchor (or map) an animal genome to another species’ reference genome. G-Anchor makes novel use of a... Read More about G-Anchor: a novel approach for whole-genome comparative mapping utilising evolutionary conserved DNA sequences.

Contrasting origin of B chromosomes in two cervids (Siberian roe deer and grey brocket deer) unravelled by chromosome-specific DNA sequencing
Journal Article
Makunin, A., Kichigin, I. G., Larkin, D. M., O'Brien, P. C. M., Ferguson-Smith, M. A., Yang, F., Proskuryakova, A. A., Vorobieva, N. V., Chernyaeva, E., O'Brien, S. J., Graphodatsky, A. S., & Trifonov, V. (in press). Contrasting origin of B chromosomes in two cervids (Siberian roe deer and grey brocket deer) unravelled by chromosome-specific DNA sequencing. BMC Genomics, 17(1), 618. https://doi.org/10.1186/s12864-016-2933-6

Novel insights into chromosome evolution in birds, archosaurs, and reptiles
Journal Article
Farré, M., Narayan, J., Slavov, G. T., Damas, J., Auvil, L., Li, C., Jarvis, E. D., Burt, D. W., Griffin, D. K., & Larkin, D. M. (in press). Novel insights into chromosome evolution in birds, archosaurs, and reptiles. Genome Biology and Evolution, 8(8), 2442-2451. https://doi.org/10.1093/gbe/evw166

Homologous synteny blocks (HSBs) and evolutionary breakpoint regions (EBRs) in mammalian chromosomes are enriched for distinct DNA features, contributing to distinct phenotypes. To reveal HSB and EBR roles in avian evolution, we performed a sequence-... Read More about Novel insights into chromosome evolution in birds, archosaurs, and reptiles.

Whole-genome resequencing of two elite sires for the detection of haplotypes under selection in dairy cattle
Journal Article
Larkin, D. M., Daetwyler, H. D., Hernandez, A. G., Wright, C. L., Hetrick, L. A., Boucek, L., Bachman, S. L., Band, M. R., Akraiko, T. V., Cohen-Zinder, M., Thimmapuram, J., Macleod, I. M., Harkins, T. T., McCague, J. E., Goddard, M. E., Hayes, B. J., & Lewin, H. A. (in press). Whole-genome resequencing of two elite sires for the detection of haplotypes under selection in dairy cattle. https://doi.org/10.1073/pnas.1114546109

Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax
Journal Article
Fang, X. D., Nevo, E., Han, L. J., Levanon, E. Y., Zhao, J., Avivi, A., Larkin, D. M., Jiang, X. T., Feranchuk, S., Zhu, Y. B., Fishman, A., Feng, Y., Sher, N., Xiong, Z. Q., Hankeln, T., Huang, Z. Y., Gorbunova, V., Zhang, L., Zhao, W., Wildman, D. E., …Wang, J. Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax. Nature Communications, 5, https://doi.org/10.1038/ncomms4966

The Genome 10K Project: A Way Forward Further
Journal Article
Koepfli, K. P., Paten, B., Antunes, A., Belov, K., Bustamante, C., Castoe, T. A., Clawson, H., Crawford, A. J., Diekhans, M., Distel, D., Durbin, R., Earl, D. A., Fujita, M. K., Gamble, T., Georges, A., Gemmell, N. J., Gilbert, M. T. P., Graves, J. M., Green, R. E., Hickey, G., …O'Brien, S. J. The Genome 10K Project: A Way Forward Further. Annual Review of Animal Biosciences, 3, 57-111. https://doi.org/10.1146/annurev-animal-090414-014900

The Genome 10K Project was established in 2009 by a consortium of biologists and genome scientists determined to facilitate the sequencing and analysis of the complete genomes of 10,000 vertebrate species. Since then the number of selected and initia... Read More about The Genome 10K Project: A Way Forward Further.

AVIAN CHROMONOMICS GOES FUNCTIONAL
Presentation / Conference Contribution
Griffin, D. K., Farré, M., Lithgow, P., O'Connor, R., Fowler, K. E., Romanov, M. N., & Larkin, D. M. AVIAN CHROMONOMICS GOES FUNCTIONAL