Toll-like receptors in domestic animals
Journal Article
Jungi, T. W., Farhat, K., Burgener, I. A., & Werling, D. Toll-like receptors in domestic animals. Cell and Tissue Research, 343(1), 107-120. https://doi.org/10.1007/s00441-010-1047-8
All Outputs (151)
Breed-independent toll-like receptor 5 polymorphisms show association with canine inflammatory bowel disease
Journal Article
Kathrani, A., House, A. K., Catchpole, B., Murphy, A. M., Werling, D., & Allenspach, K. Breed-independent toll-like receptor 5 polymorphisms show association with canine inflammatory bowel disease. Tissue Antigens, 78(2), 94-101. https://doi.org/10.1111/j.1399-0039.2011.01707.x
POLYMORPHISMS IN THE TOLL LIKE RECEPTOR 5 GENE ARE SIGNIFICANTLY ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE IN A POPULATION CONSISTING OF 38 DIFFERENT DOG BREEDS
Presentation / Conference Contribution
Kathrani, A., House, A. K., Werling, D., Catchpole, B., Murphy, A. M., & Allenspach, K. POLYMORPHISMS IN THE TOLL LIKE RECEPTOR 5 GENE ARE SIGNIFICANTLY ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE IN A POPULATION CONSISTING OF 38 DIFFERENT DOG BREEDS
CD11c(+) Cells are Significantly Decreased in the Duodenum, Ileum and Colon of Dogs with Inflammatory Bowel Disease
Journal Article
Kathrani, A., Schmitz, S., Priestnall, S. L., Smith, K. C., Werling, D., Garden, O. A., & Allenspach, K. CD11c(+) Cells are Significantly Decreased in the Duodenum, Ileum and Colon of Dogs with Inflammatory Bowel Disease. Journal of Comparative Pathology, 145(4), 359-366. https://doi.org/10.1016/j.jcpa.2011.03.010
Canine breeds at high risk of developing inflammatory bowel disease in the south-eastern UK
Journal Article
Kathrani, A., Werling, D., & Allenspach, K. Canine breeds at high risk of developing inflammatory bowel disease in the south-eastern UK. Veterinary Record, 169(24), E-pub. https://doi.org/10.1136/vr.d5380
MUTATIONAL ANALYSIS OF THE TLR5 GENE IN BOXER DOGS WITH INFLAMMATORY BOWEL DISEASE REVEALS NOVEL POLYMORPHISM IN THE LEUCINE RICH REPEAT DOMAIN
Presentation / Conference Contribution
Kathrani, A., Werling, D., & Allenspach, K. MUTATIONAL ANALYSIS OF THE TLR5 GENE IN BOXER DOGS WITH INFLAMMATORY BOWEL DISEASE REVEALS NOVEL POLYMORPHISM IN THE LEUCINE RICH REPEAT DOMAIN
POLYMORPHISMS IN TOLL-LIKE RECEPTOR 5 RESULT IN HYPER-RESPONSIVENESS TO FLAGELLIN
Presentation / Conference Contribution
Kathrani, A., Werling, D., Holder, A. L., Catchpole, B., & Allenspach, K. POLYMORPHISMS IN TOLL-LIKE RECEPTOR 5 RESULT IN HYPER-RESPONSIVENESS TO FLAGELLIN
Characterisation of antibodies to bovine toll-like receptor (TLR)-2 and cross-reactivity with ovine TLR2
Journal Article
Kwong, L. S., Parsons, R., Patterson, R., Coffey, T. J., Thonur, L., Chang, J., Russell, G., Haig, D., Werling, D., & Hope, J. C. Characterisation of antibodies to bovine toll-like receptor (TLR)-2 and cross-reactivity with ovine TLR2. Veterinary Immunology and Immunopathology, 139(2-4), 313-318. https://doi.org/10.1016/j.vetimm.2010.10.014
Evaluation of mucosal bacteria and histopathology, clinical disease activity and expression of Toll-like receptors in German shepherd dogs with chronic enteropathies
Journal Article
Allenspach, K., House, A., Smith, K., McNeill, F. M., Hendricks, A., Elson-Riggins, J. G., Riddle, A. L., Steiner, J. M., Werling, D., Garden, O. A., Catchpole, B., & Suchodolski, J. S. Evaluation of mucosal bacteria and histopathology, clinical disease activity and expression of Toll-like receptors in German shepherd dogs with chronic enteropathies. Veterinary Microbiology, 146(3-4), 326-335. https://doi.org/10.1016/j.vetmic.2010.05.025
Primary bovine colonic cells: A model to study strain-specific responses to Escherichia coli
Journal Article
Bridger, P. S., Mohr, M., Stamm, I., Frohlich, J., Follmann, W., Birkner, S., Metcalfe, H., Werling, D., Baljer, G., & Menge, C. Primary bovine colonic cells: A model to study strain-specific responses to Escherichia coli. Veterinary Immunology and Immunopathology, 137(1-2), 54-63. https://doi.org/10.1016/j.vetimm.2010.04.010
TGF-b2 induction regulates invasiveness of Theileria-Transformed Leukocytes and Disease susceptibility
Journal Article
Chaussepied, M., Janski, N., Baumgartner, M., Lizundia, R., Jensen, K., Weri, W., Shiels, B. R., Weitzmn, J. B., Glass, E. J., Werling, D., & Langsley, G. TGF-b2 induction regulates invasiveness of Theileria-Transformed Leukocytes and Disease susceptibility. PLoS Pathogens, 6(11), e1001197. https://doi.org/10.1371/journal.ppat.1001197
Evaluation of the effect of phosphodiesterase on equine platelet activation and the effect of antigen challenge on platelet phosphodiesterase activity in horses with recurrent airway obstruction
Journal Article
Dunkel, B., Rickards, K. J., Werling, D., Page, C. P., & Cunningham, F. M. Evaluation of the effect of phosphodiesterase on equine platelet activation and the effect of antigen challenge on platelet phosphodiesterase activity in horses with recurrent airway obstruction. American Journal of Veterinary Research, 71(5), 534-540. https://doi.org/10.2460/ajvr.71.5.534
Regulation of equine platelet activation by phosphodiesterase (PDE) and the effect of antigen challenge on platelet PDE in horses with recurrent airway obstruction (RAO)
Journal Article
Dunkel, B., Rickards, K. J., Werling, D., Page, C. P., & Cunningham, F. M. Regulation of equine platelet activation by phosphodiesterase (PDE) and the effect of antigen challenge on platelet PDE in horses with recurrent airway obstruction (RAO). American Journal of Veterinary Research, 71(5), 534-540. https://doi.org/10.2460/ajvr.71.5.534
Polymorphisms in the TLR4 and TLR5 gene are significantly associated with inflammatory bowel disease in German shepherd dogs.
Journal Article
Kathrani, A., House, A. K., Catchpole, B., Murphy, A., German, A., Werling, D., & Allenspach, K. Polymorphisms in the TLR4 and TLR5 gene are significantly associated with inflammatory bowel disease in German shepherd dogs. PLoS ONE, 5(12), e15740. https://doi.org/10.1371/journal.pone.0015740
OVERDOMINANT SINGLE NUCLEOTIDE POLYMORPHISMS IN THE NUCLEOTIDE OLIGOMERISATION DOMAIN TWO (NOD2) GENE ARE SIGNIFICANTLY ASSOCIATED WITH CANINE INFLAMMATORY BOWEL DISEASE
Presentation / Conference Contribution
Kathrani, A., House, A. K., Werling, D., Catchpole, B., Murphy, A., German, A. J., Lee, H., & Allenspach, K. OVERDOMINANT SINGLE NUCLEOTIDE POLYMORPHISMS IN THE NUCLEOTIDE OLIGOMERISATION DOMAIN TWO (NOD2) GENE ARE SIGNIFICANTLY ASSOCIATED WITH CANINE INFLAMMATORY BOWEL DISEASE
CD11c POSITIVE DENDRITIC CELLS ARE SIGNIFICANTLY DECREASED IN THE DUODENUM OF DOGS WITH INFLAMMATORY BOWEL DISEASE
Presentation / Conference Contribution
Kathrani, A., House, A., Werling, D., Smith, K. C., Garden, O. A., Simbi, B. H., & Allenspach, K. CD11c POSITIVE DENDRITIC CELLS ARE SIGNIFICANTLY DECREASED IN THE DUODENUM OF DOGS WITH INFLAMMATORY BOWEL DISEASE
Expression of Toll-like receptor 2 in duodenal biopsies from dogs with inflammatory bowel disease is associated with severity of disease
Journal Article
McMahon, L. A., House, A., Catchpole, B., Elson-Riggins, J. G., Riddle, A. L., Smith, K. C., Werling, D., Burgener, I. A., & Allenspach, K. Expression of Toll-like receptor 2 in duodenal biopsies from dogs with inflammatory bowel disease is associated with severity of disease. Veterinary Immunology and Immunopathology, 135(1-2), 158-163. https://doi.org/10.1016/j.vetimm.2009.11.012
Flagellin expression enhances Salmonella accumulation in TLR5-positive macrophages
Journal Article
Metcalfe, H. J., Best, A., Kanellos, T., La Radione, R. M., & Werling, D. Flagellin expression enhances Salmonella accumulation in TLR5-positive macrophages. Developmental and Comparative Immunology, 34(8), 797-804. https://doi.org/10.1016/j.dci.2010.02.008
LRRfinder: a web application for the identification of leucine-rich repeats and an integrative Toll-like receptor database
Journal Article
Offord, V., Coffey, T. J., & Werling, D. LRRfinder: a web application for the identification of leucine-rich repeats and an integrative Toll-like receptor database. Developmental and Comparative Immunology, 34(10), 1035-1041. https://doi.org/10.1016/j.dci.2010.05.004
The bovine chemokine receptors and their mRNA abundance in mononuclear phagocytes
Journal Article
Widdison, S., Siddiqui, N., Easton, V., Lawrence, F., Ashley, G., Werling, D., Watson, M., & Coffey, T. The bovine chemokine receptors and their mRNA abundance in mononuclear phagocytes. BMC Genomics, 11(439), https://doi.org/10.1186/1471-2164-11-439