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Quantitative Expression and Co-Localization of Wnt Signalling Related Proteins in Feline Squamous Cell Carcinoma (2016)
Journal Article
Giuliano, A., Swift, R., Arthurs, C., Marote, G., Abramo, F., McKay, J., Thomson, C., Beltran, M., Millar, M., Priestnall, S. L., Dobson, J., Costantino-Casas, F., Petrou, T., McGonnell, I. M., Davies, A. J., Weetman, M., Garden, O. A., Masters, J. R., Thrasivoulou, C., & Ahmed, A. (2016). Quantitative Expression and Co-Localization of Wnt Signalling Related Proteins in Feline Squamous Cell Carcinoma. PLoS ONE, 11(8), e0161103. https://doi.org/10.1371/journal.pone.0161103

Feline oral squamous cell carcinoma (FOSCC) is an aggressive neoplasm in cats. Little is known about the possible molecular mechanisms that may be involved in the initiation, maintenance and progression of FOSCC. Wnt signalling is critical in develop... Read More about Quantitative Expression and Co-Localization of Wnt Signalling Related Proteins in Feline Squamous Cell Carcinoma.

Occipital foramina development involves localised regulation of mesenchyme proliferation and is independent of apoptosis (2015)
Journal Article
Akbareian, S. E., Pitsillides, A. A., Macharia, R. G., & McGonnell, I. M. (2015). Occipital foramina development involves localised regulation of mesenchyme proliferation and is independent of apoptosis. Journal of Anatomy, 226(6), 560-574. https://doi.org/10.1111/joa.12304

Cranial foramina are holes within the skull, formed during development, allowing entry and exit of blood vessels and nerves. Once formed they must remain open, due to the vital structures they contain, i.e. optic nerves, jugular vein, carotid artery,... Read More about Occipital foramina development involves localised regulation of mesenchyme proliferation and is independent of apoptosis.

Shh regulates chick Ebf1 gene expression in somite development (2015)
Journal Article
El-Magd, M. A., Allen, S. P., McGonnell, I. M., Mansour, A. A., Otto, A., & Patel, K. (2015). Shh regulates chick Ebf1 gene expression in somite development. Gene, 554(1), 87-95. https://doi.org/10.1016/j.gene.2014.10.028

The chick early B-cell factor 1 (cEbf1) is a member of EBF family of helix loop helix transcription factors. Recently, we have proved that cEbf1 expression in feather is regulated by Shh. It is therefore possible that the somitic expression of cEbf1... Read More about Shh regulates chick Ebf1 gene expression in somite development.

Homologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropes (2014)
Journal Article
Thompson, I. R., Mirczuk, S. M., Smith, L., Lessey, A. J., Simbi, B., Sunters, A., Baxter, G. F., Lipscomb, V. J., McGonnell, I. M., Wheeler-Jones, C. P. D., Mukherjee, A., Roberson, M. S., McArdle, C. A., & Fowkes, R. C. (2014). Homologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropes. Cell and Tissue Research, 355(2), 425-36. https://doi.org/10.1007/s00441-013-1763-y

The guanylyl cyclases, GC-A and GC-B, are selective receptors for atrial and C-type natriuretic peptides (ANP and CNP, respectively). In the anterior pituitary, CNP and GC-B are major regulators of cGMP production in gonadotropes and yet mouse models... Read More about Homologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropes.

Effect of transportation duration of 1-day-old chicks on postplacement production performances and pododermatitis of broilers up to slaughter age (2013)
Journal Article
Bergoug, H., Guinebretiere, M., Tong, Q., Roulston, N., Romanini, C. E. B., Exadaktylos, V., Berckmans, D., Garain, P., Demmers, T. G. M., McGonnell, I. M., Bahr, C., Burel, C., Eterradossi, N., & Michel, V. (2013). Effect of transportation duration of 1-day-old chicks on postplacement production performances and pododermatitis of broilers up to slaughter age. Poultry Science, 92(12), 3300-3309. https://doi.org/10.3382/ps.2013-03118

This experiment studied the effect of transportation duration of 1-d-old chicks on dehydration, mortality, production performance, and pododermatitis during the growout period. Eggs from the same breeder flock (Ross PM3) were collected at 35, 45, and... Read More about Effect of transportation duration of 1-day-old chicks on postplacement production performances and pododermatitis of broilers up to slaughter age.

Expression of guanylyl cyclase-B (GC-B/NPR2) receptors in normal human fetal pituitaries and human pituitary adenomas implicates a regulatory role for C-type natriuretic peptide
Journal Article
Thompson, I. R., Chand, A. N., King, P. J., Ansorge, O., Karavitaki, N., Jones, C. A., Rahmutula, D., Gardner, D. G., Zivkovic, V., Wheeler-Jones, C. P. D., McGonnell, I. M., Korbonits, M., Anderson, R. A., Wass, J. A. H., McNeilly, A. S., & Fowkes, R. C. Expression of guanylyl cyclase-B (GC-B/NPR2) receptors in normal human fetal pituitaries and human pituitary adenomas implicates a regulatory role for C-type natriuretic peptide. Endocrine-Related Cancer, 19(4), 497-508. https://doi.org/10.1530/ERC-12-0129

DEVELOPMENTAL AND FUNCTIONAL ROLE OF CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE II (CAMKII) ISOFORMS IN NORMAL HUMAN FETAL PITUITARY, L BETA T2 GONADOTROPES AND ZEBRAFISH NEUROENDOCRINETissues
Presentation / Conference Contribution
Chand, A. C., Thompson, I. R., Akbareian, S. E., Toro, S., Anderson, R. A., McNeilly, A. S., McGonnell, I. M., & Fowkes, R. C. DEVELOPMENTAL AND FUNCTIONAL ROLE OF CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE II (CAMKII) ISOFORMS IN NORMAL HUMAN FETAL PITUITARY, L BETA T2 GONADOTROPES AND ZEBRAFISH NEUROENDOCRINETissues