Risk Factors for Development of Chronic Kidney Disease in Cats
(2016)
Journal Article
Finch, N. C., Syme, H. M., & Elliott, J. (2016). Risk Factors for Development of Chronic Kidney Disease in Cats. Journal of Veterinary Internal Medicine, 30(2), 602-610. https://doi.org/10.1111/jvim.13917
All Outputs (220)
Chronic kidney disease in aged cats: Clinical features, morphology, and proposed pathogeneses (2016)
Journal Article
Brown, C., Elliott, J., Schmiedt, C., & Brown, S. (2016). Chronic kidney disease in aged cats: Clinical features, morphology, and proposed pathogeneses. Veterinary Pathology, 53(2), 309-326. https://doi.org/10.1177/0300985815622975Chronic kidney disease (CKD) is the most common metabolic disease of domesticated cats, with most affected cats being geriatric (>12 years of age). The prevalence of CKD in cats exceeds that observed in dogs, and the frequency of the diagnosis of CKD... Read More about Chronic kidney disease in aged cats: Clinical features, morphology, and proposed pathogeneses.
Urinary active transforming growth factor ß in feline chronic kidney disease (2016)
Journal Article
Lawson, J. S., Syme, H. M., Wheeler-Jones, C. P. D., & Elliott, J. (2016). Urinary active transforming growth factor ß in feline chronic kidney disease. https://doi.org/10.1016/j.tvjl.2016.02.004The cytokine transforming growth factor beta 1 (TGF-β1) has been widely implicated in the development and progression of renal fibrosis in chronic kidney disease (CKD) in humans and in experimental models. The aims of this study were to assess the as... Read More about Urinary active transforming growth factor ß in feline chronic kidney disease.
Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney (2015)
Journal Article
Pelligand, L., Suemanotham, N., King, J. N., Seewald, W., Syme, H. M., Smith, K. C., Lees, P., & Elliott, J. (2015). Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney. BMC Veterinary Research, 11(296), https://doi.org/10.1186/s12917-015-0598-z
Relationship between plasma fibroblast growth factor-23 concentration and survival time in cats with chronic kidney disease (2015)
Journal Article
Geddes, R. F., Elliott, J., & Syme, H. M. (2015). Relationship between plasma fibroblast growth factor-23 concentration and survival time in cats with chronic kidney disease. Journal of Veterinary Internal Medicine, 29(6), 1494-1501. https://doi.org/10.1111/jvim.13625
Randomized placebo-controlled clinical trial of a new chewable formulation of amlodipine for the treatment of hypertension in client-owned cats (2015)
Journal Article
Huhtinen, M., Derre, G., Renoldi, H. J., Rinkinen, M., Adler, K., Aspegren, J., Zemirline, C., & Elliott, J. (2015). Randomized placebo-controlled clinical trial of a new chewable formulation of amlodipine for the treatment of hypertension in client-owned cats. Journal of Veterinary Internal Medicine, 29(3), 786-793. https://doi.org/10.1111/jvim.12589
Feline Chronic Kidney Disease Is Associated with Upregulation of Transglutaminase 2: A Collagen Cross-Linking Enzyme (2015)
Journal Article
Sanchez-Lara, A. C., Elliott, J., Syme, H. M., Brown, C. A., & Haylor, J. L. (2015). Feline Chronic Kidney Disease Is Associated with Upregulation of Transglutaminase 2: A Collagen Cross-Linking Enzyme. Veterinary Pathology, 52(3), 513-523. https://doi.org/10.1177/0300985814542811Chronic kidney disease is a major cause of morbidity and mortality in cats. Transglutaminase 2 (TG2) is a calcium-dependent enzyme proposed to mediate tubulointerstitial fibrosis in the kidney by cross-linking collagen fibrils. Postmortem kidney tiss... Read More about Feline Chronic Kidney Disease Is Associated with Upregulation of Transglutaminase 2: A Collagen Cross-Linking Enzyme.
Changes in systolic blood pressure over time in healthy cats and cats with chronic kidney disease (2015)
Journal Article
Bijsmans, E. S., Jepson, R. E., Chang, Y. M., Syme, H. M., & Elliott, J. (2015). Changes in systolic blood pressure over time in healthy cats and cats with chronic kidney disease. Journal of Veterinary Internal Medicine, 29(3), 855-61. https://doi.org/10.1111/jvim.12600
Clinical Severity Score System in Dogs with Degenerative Mitral Valve Disease (2015)
Journal Article
Lopez-Alvarez, J., Elliott, J., Pfeiffer, D. U., Chang, Y. M., Mattin, M. J., Moonarmart, W., Hezzell, M. J., & Boswood, A. (2015). Clinical Severity Score System in Dogs with Degenerative Mitral Valve Disease. Journal of Veterinary Internal Medicine, 29(2), 575-581. https://doi.org/10.1111/jvim.12544
Determination of extracellular fluid volume in healthy and azotemic cats (2015)
Journal Article
Finch, N. C., Heiene, R., Elliott, J., Syme, H. M., & Peters, A. M. (2015). Determination of extracellular fluid volume in healthy and azotemic cats. Journal of Veterinary Internal Medicine, 29(1), 35-42. https://doi.org/10.1111/jvim.12506
Nausea: Current knowledge of mechanisms, measurement and clinical impact (2015)
Journal Article
Kenward, H., Pelligand, L., Savary-Bataille, K., & Elliott, J. (2015). Nausea: Current knowledge of mechanisms, measurement and clinical impact. https://doi.org/10.1016/j.tvjl.2014.10.007
Renal fibrosis in feline chronic kidney disease: known mediators and mechanisms of injury (2015)
Journal Article
Lawson, J. S., Elliott, J., Wheeler-Jones, C. P. D., Syme, H. M., & Jepson, R. E. (2015). Renal fibrosis in feline chronic kidney disease: known mediators and mechanisms of injury. https://doi.org/10.1016/j.tvjl.2014.10.009Chronic kidney disease (CKD) is a common medical condition of ageing cats. In most cases the underlying aetiology is unknown, but the most frequently reported pathological diagnosis is renal tubulointerstitial fibrosis. Renal fibrosis, characterised... Read More about Renal fibrosis in feline chronic kidney disease: known mediators and mechanisms of injury.
Cardiovascular effects of dietary salt intake in aged healthy cats: a 2-year prospective randomized, blinded, and controlled study (2014)
Journal Article
Chetboul, V., Reynolds, B. S., Trehiou-Sechi, E., Nguyen, P., Concordet, D., Sampedrano, C. C., Testault, I., Elliott, J., Abadie, J., Biourge, V., & Lefebvre, H. P. (2014). Cardiovascular effects of dietary salt intake in aged healthy cats: a 2-year prospective randomized, blinded, and controlled study. PLoS ONE, 9(6), e97862. https://doi.org/10.1371/journal.pone.0097862High salt dry expanded diets are commercially available for cats to increase water intake and urine volume, as part of the prevention or treatment of naturally occurring urinary stone formation (calcium oxalates and struvites). However, chronic high... Read More about Cardiovascular effects of dietary salt intake in aged healthy cats: a 2-year prospective randomized, blinded, and controlled study.
Assessment of low-dose cisplatin as a model of nausea and emesis in beagle dogs, potential for repeated administration (2014)
Journal Article
Kenward, H., Pelligand, L., & Elliott, J. (2014). Assessment of low-dose cisplatin as a model of nausea and emesis in beagle dogs, potential for repeated administration. Experimental Brain Research, 232(8), 2685-2697. https://doi.org/10.1007/s00221-014-3961-6Cisplatin is a highly emetogenic cancer chemotherapy agent, which is often used to induce nausea and emesis in animal models. The cytotoxic properties of cisplatin also cause adverse events that negatively impact on animal welfare preventing repeated... Read More about Assessment of low-dose cisplatin as a model of nausea and emesis in beagle dogs, potential for repeated administration.
The effect of exercise on plasma concentrations of inflammatory markers in normal and previously laminitic ponies (2014)
Journal Article
Menzies-Gow, N. J., Wray, H., Bailey, S. R., Harris, P. A., & Elliott, J. (2014). The effect of exercise on plasma concentrations of inflammatory markers in normal and previously laminitic ponies. Equine Veterinary Journal, 46(3), 317-321. https://doi.org/10.1111/evj.12132
Differential pharmacokinetics and pharmacokinetic/pharmacodynamic modelling of robenacoxib and ketoprofen in a feline model of inflammation (2014)
Journal Article
Pelligand, L., King, J. N., Hormazabal, V., Toutain, P. L., Elliott, J., & Lees, P. (2014). Differential pharmacokinetics and pharmacokinetic/pharmacodynamic modelling of robenacoxib and ketoprofen in a feline model of inflammation. Journal of Veterinary Pharmacology and Therapeutics, 37(4), 354-366. https://doi.org/10.1111/jvp.12107Robenacoxib and ketoprofen are acidic nonsteroidal anti‐inflammatory drugs (NSAIDs). Both are licensed for once daily administration in the cat, despite having short blood half‐lives. This study reports the pharmacokinetic/pharmacodynamic (PK/PD) mod... Read More about Differential pharmacokinetics and pharmacokinetic/pharmacodynamic modelling of robenacoxib and ketoprofen in a feline model of inflammation.
Plasma renin activity and aldosterone concentrations in hypertensive cats with and without azotemia and in response to treatment with amlodipine besylate (2014)
Journal Article
Jepson, R. E., Syme, H. M., & Elliott, J. (2014). Plasma renin activity and aldosterone concentrations in hypertensive cats with and without azotemia and in response to treatment with amlodipine besylate. Journal of Veterinary Internal Medicine, 28(1), 144-53. https://doi.org/10.1111/jvim.12240
Chronic Kidney Disease in Dogs in UK Veterinary Practices: Prevalence, Risk Factors, and Survival (2013)
Journal Article
O'Neill, D. G., Elliott, J., Church, D. B., McGreevy, P. D., Thomson, P. C., & Brodbelt, D. C. (2013). Chronic Kidney Disease in Dogs in UK Veterinary Practices: Prevalence, Risk Factors, and Survival. Journal of Veterinary Internal Medicine, 27(4), 814-821. https://doi.org/10.1111/jvim.12090
Subclinical hyperthyroidism in cats: A spontaneous model of subclinical toxic nodular goiter in humans?
Journal Article
Wakeling, J., Smith, K. C., Scase, T., Kirkby, R., Elliott, J., & Syme, H. M. Subclinical hyperthyroidism in cats: A spontaneous model of subclinical toxic nodular goiter in humans?. https://doi.org/10.1089/thy.2007.0225Introduction and Objectives: Hyperthyroidism in cats, caused by nodular hyperplasia or adenomas, is clinically and histologically similar to toxic nodular goiter in humans. Subclinical hyperthyroidism in humans is defined as low thyrotropin (TSH) in... Read More about Subclinical hyperthyroidism in cats: A spontaneous model of subclinical toxic nodular goiter in humans?.
Characterisation of the response of equine digital arteries and veins to substance P
Journal Article
Katz, L. M., Marr, C. M., & Elliott, J. Characterisation of the response of equine digital arteries and veins to substance P. Journal of Veterinary Pharmacology and Therapeutics, 26(5), 361-368. https://doi.org/10.1046/j.1365-2885.2003.00491.x