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Avian Papilloma and Squamous Cell Carcinoma: a Histopathological, Immunohistochemical and Virological study (2020)
Journal Article
Jones, A. L., Suárez-Bonnet, A., Mitchell, J. A., Ramirez, G. A., Stidworthy, M. F., & Priestnall, S. L. (2020). Avian Papilloma and Squamous Cell Carcinoma: a Histopathological, Immunohistochemical and Virological study. Journal of Comparative Pathology, 175, 13-23. https://doi.org/10.1016/j.jcpa.2019.11.007

In this retrospective study, we describe the histopathological findings in seven papillomas and 45 squamous cell carcinomas (SCCs) from psittacine birds, raptors and domestic fowl. The age of affected birds ranged from 3 to 40 years, with median age... Read More about Avian Papilloma and Squamous Cell Carcinoma: a Histopathological, Immunohistochemical and Virological study.

Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells (2018)
Journal Article
Szczepanski, A., Owczarek, K., Milewska, A., Baster, Z., Rajfur, Z., Mitchell, J. A., & Pyrc, K. (2018). Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells. Veterinary Research, 49, 55. https://doi.org/10.1186/s13567-018-0551-9

Canine respiratory coronavirus (CRCoV), identified in 2003, is a member of the Coronaviridae family. The virus is a betacoronavirus and a close relative of human coronavirus OC43 and bovine coronavirus. Here, we examined entry of CRCoV into human rec... Read More about Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells.

European surveillance of emerging pathogens associated with canine infectious respiratory disease (2017)
Journal Article
Mitchell, J. A., Cardwell, J. M., Leach, H., Walker, C. A., Le Poder, S., Decaro, N., …Brownlie, J. (2017). European surveillance of emerging pathogens associated with canine infectious respiratory disease. Veterinary Microbiology, 212, 31-38. https://doi.org/10.1016/j.vetmic.2017.10.019

Canine infectious respiratory disease (CIRD) is a major cause of morbidity in dogs worldwide, and is associated with a number of new and emerging pathogens. In a large multi-centre European study the prevalences of four key emerging CIRD pathogens; c... Read More about European surveillance of emerging pathogens associated with canine infectious respiratory disease.

Evidence for human norovirus infection of dogs in the UK (2015)
Journal Article
Caddy, S. L., De Rougemont, A., Emmott, E., El-Attar, L. M. R., Mitchell, J. A., Hollinshead, M., …Goodfellow, I. (2015). Evidence for human norovirus infection of dogs in the UK. Journal of Clinical Microbiology, 53(6), 1873-1883. https://doi.org/10.1128/JCM.02778-14

Human noroviruses (HuNoVs) are a major cause of viral gastroenteritis, with an estimated 3 million cases per year in the United Kingdom. HuNoVs have recently been isolated from pet dogs in Europe (M. Summa, C.-H. von Bonsdorff, and L. Maunula, J Clin... Read More about Evidence for human norovirus infection of dogs in the UK.

Canine Respiratory Coronavirus, Bovine Coronavirus, and Human Coronavirus OC43: Receptors and Attachment Factors
Journal Article
Szczepanski, A., Owczarek, K., Bzowska, M., Gula, K., Drebot, I., Ochman, M., …Pyrc, K. (in press). Canine Respiratory Coronavirus, Bovine Coronavirus, and Human Coronavirus OC43: Receptors and Attachment Factors. Viruses, 11(4), 328. https://doi.org/10.3390/v11040328

Despite high similarity of canine respiratory coronavirus (CRCoV), bovine coronavirus, (BCoV) and human coronavirus OC43 (HCoV-OC43), these viruses differ in species specificity. For years it was believed that they share receptor specificity, utilizi... Read More about Canine Respiratory Coronavirus, Bovine Coronavirus, and Human Coronavirus OC43: Receptors and Attachment Factors.

Clinical Signs, Neuroanatomical Distribution and Histopathological Characterization of Meningoencephalitis in Wild Red Foxes (Vulpes vulpes) Associated with a Novel Fox Circovirus
Journal Article
Stoll, A. L., Mitchell, J. A., & Priestnall, S. L. Clinical Signs, Neuroanatomical Distribution and Histopathological Characterization of Meningoencephalitis in Wild Red Foxes (Vulpes vulpes) Associated with a Novel Fox Circovirus. Journal of Comparative Pathology, https://doi.org/10.1016/j.jcpa.2016.05.013

EFFICACY AND SAFETY OF MAVACOXIB IN COMPARISON WITH CARPROFEN IN THE TREATMENT OF PAIN AND INFLAMMATION ASSOCIATED WITH DEGENERATIVE JOINT DISEASE IN DOGS PRESENTED AS VETERINARY PATIENTS
Journal Article
Six, H., Mitchell, J. A., Anton, C., Siedek, E., Tena, J. K., & Stegemann, M. R. EFFICACY AND SAFETY OF MAVACOXIB IN COMPARISON WITH CARPROFEN IN THE TREATMENT OF PAIN AND INFLAMMATION ASSOCIATED WITH DEGENERATIVE JOINT DISEASE IN DOGS PRESENTED AS VETERINARY PATIENTS. Journal of Veterinary Pharmacology and Therapeutics, 35, 56-56

Development of a quantitative real-time PCR for the detection of canine respiratory coronavirus
Journal Article
Mitchell, J. A., Brooks, H. W., Shiu, K., Brownlie, J., & Erles, K. Development of a quantitative real-time PCR for the detection of canine respiratory coronavirus. Journal of Virological Methods, 155(2), 136-142. https://doi.org/10.1016/j.jviromet.2008.10.008

Canine respiratory coronavirus (CRCoV) has been detected recently in dogs with canine infectious respiratory disease and is involved in the clinical disease complex. CRCoV is a group 2 coronavirus most closely related to bovine coronavirus and human... Read More about Development of a quantitative real-time PCR for the detection of canine respiratory coronavirus.

Quantification of mRNA encoding cytokines and chemokines and assessment of ciliary function in canine tracheal epithelium during infection with canine respiratory coronavirus (CRCoV)
Journal Article
Priestnall, S. L., Mitchell, J. A., Brooks, H. W., Brownlie, J., & Erles, K. Quantification of mRNA encoding cytokines and chemokines and assessment of ciliary function in canine tracheal epithelium during infection with canine respiratory coronavirus (CRCoV). Veterinary Immunology and Immunopathology, 127(1-2), 38-46. https://doi.org/10.1016/j.vetimm.2008.09.017

One of the first lines of defence against viral infection is the innate immune response and the induction of antiviral type I interferons (IFNs). However some viruses, including the group 2 coronaviruses, have evolved mechanisms to overcome or circum... Read More about Quantification of mRNA encoding cytokines and chemokines and assessment of ciliary function in canine tracheal epithelium during infection with canine respiratory coronavirus (CRCoV).