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Conformational eyelid disorders in dogs under primary veterinary care in the UK - Epidemiology and clinical management (2025)
Journal Article
O'Neill, D., Mustikka, M. P., Brodbelt, D. C., Church, D. B., & Vaattovaara, V. (2025). Conformational eyelid disorders in dogs under primary veterinary care in the UK - Epidemiology and clinical management. Herpetological Conservation and Biology, 20(6), e0326526. https://doi.org/10.1371/journal.pone.0326526

Introduction Natural eyelid conformation is essential for normal function and health of the ocular surface. However, many modern dog types are deliberately bred for abnormal eyelid conformation associated with severe health and welfare issues. This s... Read More about Conformational eyelid disorders in dogs under primary veterinary care in the UK - Epidemiology and clinical management.

Synopsis of the antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID) (2025)
Journal Article
Loeffler, A., Cain, C., Ferrer, L., Nishifuji, K., Varjonen, K., Papich, M., Guardabassi, L., Frosini, S., Barker, E., & Weese, S. (2025). Synopsis of the antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID). Veterinary Dermatology, https://doi.org/10.1111/vde.13365

BackgroundCanine pyoderma is one of the most common presentations in small animal practice, frequently leading to antimicrobial prescribing.ObjectivesTo provide clinicians with antimicrobial treatment guidelines for staphylococcal pyoderma, including... Read More about Synopsis of the antimicrobial use guidelines for canine pyoderma by the International Society for Companion Animal Infectious Diseases (ISCAID).

Selection for florfenicol resistance at sub-MIC concentrations in Pasteurella multocida. (2025)
Journal Article
Hughes, A., Pelligand, L., Andersson, D., & Mead, A. (2025). Selection for florfenicol resistance at sub-MIC concentrations in Pasteurella multocida. PLoS ONE, https://doi.org/10.1371/journal.pone.0327115

Antimicrobial resistance is a global threat to both human and animal health, and transfer of resistance between these spheres is recognised as a key concern for all species. Selection for resistance at sub-inhibitory antimicrobial concentrations has... Read More about Selection for florfenicol resistance at sub-MIC concentrations in Pasteurella multocida..

Development and characterisation of improved unifocal primary mouse lung cancer models with metastatic potential (2025)
Journal Article
Pedrosa, A., Castillo-Kauil, A., Kravchuk, Y., Reynolds, L., Williams, B., Moore, D., Lang, C., Allanki, S., Maniati, E., Hardas, A., Haj, J., Drake, R., Cleaver, J., Foster, J., Kim, J., Stern, E., Sosabowski, J., Fruhwirth, G., Sahai, E., Wald, O., & Hodivala-Dilke, K. (2025). Development and characterisation of improved unifocal primary mouse lung cancer models with metastatic potential. Journal of Pathology, https://doi.org/10.1002/path.6435

Lung cancer is the leading cause of cancer-related death globally. To better understand the biology of lung cancer, mouse models have been developed using either tail vein-injected tumour cell lines or genetically modified mice. The current gold-stan... Read More about Development and characterisation of improved unifocal primary mouse lung cancer models with metastatic potential.

Emulating the EPIC trial using VetCompass primary-care data: causal effects of pimobendan in UK dogs with grade IV/VI heart murmurs (2025)
Journal Article
Pegram, C., Diaz-Ordaz, K., Brodbelt, D. C., Chang, Y.-M., Boswood, A., Wilshaw, J., Reep, C. A. T., Balling, S., Sahota, J., Church, D. B., & O’Neill, D. G. (2025). Emulating the EPIC trial using VetCompass primary-care data: causal effects of pimobendan in UK dogs with grade IV/VI heart murmurs. PLoS ONE, 20(6), e0325695. https://doi.org/10.1371/journal.pone.0325695

Frequency, Risk Factors, and Mortality for Diabetes Mellitus in 1 225 130 Cats Under Primary Veterinary Care in the United Kingdom in 2019 (2025)
Journal Article
Waite, O., O'Neill, D. G., Wright, E., Gostelow, R., Jepson, R. E., & Brodbelt, D. C. (2025). Frequency, Risk Factors, and Mortality for Diabetes Mellitus in 1 225 130 Cats Under Primary Veterinary Care in the United Kingdom in 2019. Herpetological Conservation and Biology, 39(4), e70161. https://doi.org/10.1111/jvim.70161

Background: Diabetes mellitus (DM) is a common endocrinopathy in cats. General population epidemiology and mortality
studies on DM are lacking.
Objectives: Describe the incidence, prevalence, risk factors, and mortality for DM in cats under primary... Read More about Frequency, Risk Factors, and Mortality for Diabetes Mellitus in 1 225 130 Cats Under Primary Veterinary Care in the United Kingdom in 2019.

Repeated Low‐Level Inflammatory Challenge Leads to Alterations in the TNF‐CXCL10 Signalling Pathway in Mouse Cerebral Endothelial Cells In Vitro (2025)
Journal Article
Ritson, M., Xia, D., Wheeler‐Jones, C., & Stolp, H. B. (2025). Repeated Low‐Level Inflammatory Challenge Leads to Alterations in the TNF‐CXCL10 Signalling Pathway in Mouse Cerebral Endothelial Cells In Vitro. Journal of Neurochemistry, 169(6), e70130. https://doi.org/10.1111/jnc.70130

The mechanism by which chronic systemic inflammation contributes to cerebral endothelial dysfunction and neurological disorders is unclear, although endothelial inflammatory signalling is considered a cornerstone of this process. Here, we have perfor... Read More about Repeated Low‐Level Inflammatory Challenge Leads to Alterations in the TNF‐CXCL10 Signalling Pathway in Mouse Cerebral Endothelial Cells In Vitro.

Desmitis of the palmar or plantar ligaments of the proximal interphalangeal joint: A descriptive case series (2025)
Journal Article
Peeters, M., Ott, S., van Veggel, E., Berner, D., & Perrier, M. (2025). Desmitis of the palmar or plantar ligaments of the proximal interphalangeal joint: A descriptive case series. Equine Veterinary Journal, https://doi.org/10.1111/evj.14547

BackgroundLimited reports in the literature are available regarding desmitis of the palmar/plantar ligaments of the proximal interphalangeal joint (PL-PIPJ); the clinical significance of such injuries is unknown.ObjectivesTo describe the ability to d... Read More about Desmitis of the palmar or plantar ligaments of the proximal interphalangeal joint: A descriptive case series.

Epidemiology and clinical management of acute diarrhoea in dogs under primary veterinary care in the UK (2025)
Journal Article
O'Neill, D., Prisk, L. J., Brodbelt, D. C., Church, D. B., & Allerton, F. (2025). Epidemiology and clinical management of acute diarrhoea in dogs under primary veterinary care in the UK. PLoS ONE, 20(6), e0324203. https://doi.org/10.1371/journal.pone.0324203

Background
Acute diarrhoea is a common canine veterinary presentation in the UK. This study
aimed to report the incidence, demographic risk factors and clinical management for
acute diarrhoea diagnosed under primary veterinary care in the UK in 20... Read More about Epidemiology and clinical management of acute diarrhoea in dogs under primary veterinary care in the UK.

Evaluation of Decreased Kidney Function in Dogs Receiving Carboplatin: A Retrospective Cohort Study of 98 Dogs (2006–2024) (2025)
Journal Article
Yale, A., So, A., Guillen, A., Desmas-Bazelle, I., Rogato, F., & Jepson, R. (2025). Evaluation of Decreased Kidney Function in Dogs Receiving Carboplatin: A Retrospective Cohort Study of 98 Dogs (2006–2024). Veterinary and Comparative Oncology, https://doi.org/10.1111/vco.13069

Decreased kidney function is observed in some people receiving carboplatin, but limited literature explores this in dogs. The aim of this study was to evaluate the incidence and risk factors for decreased kidney function in dogs receiving carboplatin... Read More about Evaluation of Decreased Kidney Function in Dogs Receiving Carboplatin: A Retrospective Cohort Study of 98 Dogs (2006–2024).

Survival time and prognostic factors in dogs clinically diagnosed with haemangiosarcoma in UK first opinion practice (2025)
Journal Article
Taylor, C., Barry, G. J., O’Neill, D. G., Guillén, A., Price, P. P., Labadie, J., & Brodbelt, D. C. (2025). Survival time and prognostic factors in dogs clinically diagnosed with haemangiosarcoma in UK first opinion practice. PLoS ONE, 20(6), e0316066. https://doi.org/10.1371/journal.pone.0316066

Visceral haemangiosarcoma is considered clinically aggressive in dogs, with perceived
poor prognosis often leading to euthanasia at presentation. This study aimed
to determine survival times and prognostic factors in dogs with haemangiosarcoma
und... Read More about Survival time and prognostic factors in dogs clinically diagnosed with haemangiosarcoma in UK first opinion practice.

Estimating epidemic dynamics with genomic and time series data (2025)
Journal Article
Zarebski, A., Zwaans, A., Gutierrez, B., du Plessis, L., & Pybus, O. (2025). Estimating epidemic dynamics with genomic and time series data. Journal of the Royal Society, Interface, 22(227), https://doi.org/10.1098/rsif.2024.0632

Accurately estimating the prevalence and transmissibility of an infectious disease is an important task in genetic infectious disease epidemiology. However, generating accurate estimates of these quantities, that make use of both epidemic time series... Read More about Estimating epidemic dynamics with genomic and time series data.

Quantifying the zoonotic risk profile of European influenza A viruses in swine from 2010 to 2020 inclusive (2025)
Journal Article
Coggon, A., Lopes, S., Simon, G., Arendsee, Z., Chen, K., Chiapponi, C., Essen, S., Everett, H., Hervé, S., Hufnagel, D., Mollett, B., Moreno, A., Pekosz, A., Richard, G., Rothman, R., Shaw-Saliba, K., Van Reeth, K., Venkatesh, D., Brown, I., Anderson, T., …Lewis, N. (2025). Quantifying the zoonotic risk profile of European influenza A viruses in swine from 2010 to 2020 inclusive. Journal of Virology, https://doi.org/10.1128/jvi.00306-25

H1 and H3 influenza A viruses (IAVs) circulating in European pigs are markedly distinct from those circulating in other global swine populations. These viruses exhibit significant genetic diversity, further expanded by periodic interspecies transmiss... Read More about Quantifying the zoonotic risk profile of European influenza A viruses in swine from 2010 to 2020 inclusive.

Intraguild competition mediates human avoidance in an endangered African large carnivore (2025)
Journal Article
Abrahms, B., Rafiq, K., Nisi, A., Jordan, N., Wilson, A., Loveridge, A., Kotze, R., Sousa, L., & McNutt, J. (2025). Intraguild competition mediates human avoidance in an endangered African large carnivore. Proceedings of the Royal Society B: Biological Sciences, 292(2048), https://doi.org/10.1098/rspb.2024.2835

The anthropogenic refuge (i.e. human shield) effect is a well-documented consequence of anthropogenic disturbance, whereby prey or subordinate competitors use human-dominated areas to avoid dominant predators. While this effect has been widely demons... Read More about Intraguild competition mediates human avoidance in an endangered African large carnivore.

Validation and evaluation of Lateral Flow Tests for the Detection of Antimicrobial Residues on Poultry Feathers (2025)
Journal Article
Hedges, S., Mompelat, S., Hurtaud-Pessel, D., Blake, D., Fournié, G., & Pelligand, L. (2025). Validation and evaluation of Lateral Flow Tests for the Detection of Antimicrobial Residues on Poultry Feathers. Journal of Veterinary Pharmacology and Therapeutics, https://doi.org/10.1111/jvp.70000

Persistence of antimicrobial drugs (AMDs) administered to poultry is longer in feathers than in edible tissues. Hence poultry feathers are a suitable matrix to investigate historical exposure contributing to antimicrobial resistance, since current de... Read More about Validation and evaluation of Lateral Flow Tests for the Detection of Antimicrobial Residues on Poultry Feathers.

A mapping review of worldwide current and previous cohort research programmes in cats and dogs (2025)
Journal Article
Landolt, J. I., O'Neill, D. G., Unterer, S., Hartnack, S., & Kowalska, M. E. (2025). A mapping review of worldwide current and previous cohort research programmes in cats and dogs. PLoS ONE, 20(6), e0321007. https://doi.org/10.1371/journal.pone.0321007

Cohort research programmes follow individuals over time to enable study of effects
from various factors on health or other outcomes. To date, the global distribution of
formal cohort programmes in cats and dogs has not been mapped, and a comprehens... Read More about A mapping review of worldwide current and previous cohort research programmes in cats and dogs.

Emergency and critical care services in Somalia: a cross-sectional nationwide hospital assessment using the WHO Hospital Emergency Unit assessment tool (2025)
Journal Article
Njiru, H., Relan, P., Malik, S., Abdullah, A., Shube, M., Abubakar, A., Nur, I., Osman, A., Sonethal, P., Rouhani, S., Olayo, B., Ohno, N., Sindani, I., Osman, A., Hossain, M., James, N., Alabesat, M., & Derow, M. (2025). Emergency and critical care services in Somalia: a cross-sectional nationwide hospital assessment using the WHO Hospital Emergency Unit assessment tool. BMC Emergency Medicine, 25(1), https://doi.org/10.1186/s12873-025-01234-8

BackgroundData on emergency and critical care services in Somalia and other countries with fragile and conflict-affected (FCA) situations are limited, although the burden of emergency health conditions remain high. Improving emergency care services c... Read More about Emergency and critical care services in Somalia: a cross-sectional nationwide hospital assessment using the WHO Hospital Emergency Unit assessment tool.