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β-Hydroxybutyrate-induced mitochondrial DNA (mtDNA) release mediated innate inflammatory response in bovine mammary epithelial cells by inhibiting autophagy (2025)
Journal Article
Huo, Y., Shen, T., Feng, T., Li, M., Zhao, W., Loor, J., Aernouts, B., Psifidi, A., & Xu, C. (2025). β-Hydroxybutyrate-induced mitochondrial DNA (mtDNA) release mediated innate inflammatory response in bovine mammary epithelial cells by inhibiting autophagy. Journal of Animal Science and Biotechnology, 16(1), https://doi.org/10.1186/s40104-024-01143-z

BackgroundIn perinatal dairy cows, ketosis is a prevalent metabolic disorder that lowers milk output and performance. Mitochondrial dysfunction and chronic inflammation in mammary tissue are linked to elevated blood ketone levels, particularly beta-h... Read More about β-Hydroxybutyrate-induced mitochondrial DNA (mtDNA) release mediated innate inflammatory response in bovine mammary epithelial cells by inhibiting autophagy.

Impact of commercial gut health interventions on caecal metagenome and broiler performance (2025)
Journal Article
Pangga, G., Star-Shirko, B., Psifidi, A., Xia, D., Corcionivoschi, N., Kelly, C., Hughes, C., Lavery, U., Richmond, A., Ijaz, U., & Gundogdu, O. (2025). Impact of commercial gut health interventions on caecal metagenome and broiler performance. Microbiome, 13(1), https://doi.org/10.1186/s40168-024-02012-7

BackgroundMaintaining gut health is a persistent and unresolved challenge in the poultry industry. Given the critical role of gut health in chicken performance and welfare, there is a pressing need to identify effective gut health intervention (GHI)... Read More about Impact of commercial gut health interventions on caecal metagenome and broiler performance.

Beagles kept as companion animals in the UK – demography, disorders and mortality (2025)
Journal Article
O'Neill, D., Schiksnis, M. R., Brodbelt, D. C., Church, D. B., Goldberg, S., & Engdahl, K. S. (2025). Beagles kept as companion animals in the UK – demography, disorders and mortality. Companion Animal Health and Genetics, 12(1), https://doi.org/10.1186/s40575-024-00140-9

Background Beagles are a popular companion animal dog breed and are generally stated to be a healthy breed.
This VetCompass study aimed to report the demography, common disorders and mortality of Beagles under primary
veterinary care in the UK. Ano... Read More about Beagles kept as companion animals in the UK – demography, disorders and mortality.

Whole genome sequencing revealed high occurrence of antimicrobial resistance genes in bacteria isolated from poultry manure (2025)
Journal Article
Tripathi, A., Jaiswal, A., Kumar, D., Pandit, R., Blake, D., Tomley, F., Joshi, M., Joshi, C., & Dubey, S. (2025). Whole genome sequencing revealed high occurrence of antimicrobial resistance genes in bacteria isolated from poultry manure. International Journal of Antimicrobial Agents, 65(3), https://doi.org/10.1016/j.ijantimicag.2025.107452

Background: Global demand for food has driven expansion and intensification of livestock production, particularly in developing nations where antibiotic use is often routine. Waste from poultry production, including manure, is commonly utilized as fe... Read More about Whole genome sequencing revealed high occurrence of antimicrobial resistance genes in bacteria isolated from poultry manure.

Development and Progression of Bovine Respiratory Disease Measured Using Clinical Respiratory Scoring and Thoracic Ultrasonography in Preweaned Calves on Dairy Farms in the United Kingdom: A Prospective Cohort Study (2025)
Journal Article
Lindley, G., Blackie, N., Wathes, D. C., & Booth, R. E. (in press). Development and Progression of Bovine Respiratory Disease Measured Using Clinical Respiratory Scoring and Thoracic Ultrasonography in Preweaned Calves on Dairy Farms in the United Kingdom: A Prospective Cohort Study. Animals, 15(3), 360. https://doi.org/10.3390/ani15030360

The respiratory health of preweaned calves is an important determinant of their health, welfare, and future performance. This prospective cohort study measured bovine respiratory disease (BRD) on 16 dairy farms, including 476 calves in South-west Eng... Read More about Development and Progression of Bovine Respiratory Disease Measured Using Clinical Respiratory Scoring and Thoracic Ultrasonography in Preweaned Calves on Dairy Farms in the United Kingdom: A Prospective Cohort Study.

Pro-cumulin addition in a biphasic in vitro oocyte maturation system modulates human oocyte and cumulus cell transcriptomes (2025)
Journal Article
Cava-Cami, B., Galvao, A., Van Ranst, H., Stocker, W., Harrison, C., Smitz, J., De Vos, M., Kelsey, G., & Anckaert, E. (2025). Pro-cumulin addition in a biphasic in vitro oocyte maturation system modulates human oocyte and cumulus cell transcriptomes. Molecular Human Reproduction, 31(1), https://doi.org/10.1093/molehr/gaaf001

Biphasic IVM can be offered as a patient-friendly alternative to conventional ovarian stimulation in IVF patients predicted to be hyper-responsive to ovarian stimulation. However, cumulative live birth rates after IVM per cycle are lower than after c... Read More about Pro-cumulin addition in a biphasic in vitro oocyte maturation system modulates human oocyte and cumulus cell transcriptomes.

Identifying patient subgroups in the heterogeneous chronic pain population using cluster analysis (2025)
Journal Article
Rijsdijk, M., Smits, H., Azizoglu, H., Brugman, S., van de Burgt, Y., Charldorp, T., Gelder, D., Grauw, J., Lange, E., Meye, F., Strick, M., Walravens, H., Winkens, L., Huygen, F., Drylewicz, J., & Willemen, H. (2025). Identifying patient subgroups in the heterogeneous chronic pain population using cluster analysis. The Journal of Pain, 28, https://doi.org/10.1016/j.jpain.2025.104792

Chronic pain is an ill-defined disease with complex biopsychosocial aspects, posing treatment challenges. We hypothesized that treatment failure results, at least partly, from limited understanding of diverse patient subgroups. We aimed to identify s... Read More about Identifying patient subgroups in the heterogeneous chronic pain population using cluster analysis.

Imported seafood is a reservoir of Enterobacteriaceae carrying CTX-M-encoding genes of high clinical relevance (2025)
Journal Article
Pearce, R., Pirolo, M., Goecke, N., Toppi, V., Good, L., Guitian, J., & Guardabassi, L. (2025). Imported seafood is a reservoir of Enterobacteriaceae carrying CTX-M-encoding genes of high clinical relevance. International Journal of Food Microbiology, 430, https://doi.org/10.1016/j.ijfoodmicro.2025.111063

We determined the frequency, genotypes, phenotypes, and mobility of extended-spectrum beta-lactamase (ESBL)encoding genes in Enterobacteriaceae isolated from retail seafood products. Overall, 288 samples of fresh shrimps, catfish and seabass imported... Read More about Imported seafood is a reservoir of Enterobacteriaceae carrying CTX-M-encoding genes of high clinical relevance.

Effectiveness of vapocoolant spray compared to eutectic lidocaine/prilocaine cream to enhance tolerance during intravenous catheterisation: a randomised controlled trial (2025)
Journal Article
Trinder, R., Pak, J., Humm, K., & Cole, L. (2025). Effectiveness of vapocoolant spray compared to eutectic lidocaine/prilocaine cream to enhance tolerance during intravenous catheterisation: a randomised controlled trial. Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13825

ObjectivesTo determine if tolerance of intravenous catheterisation differs following the application of vapocoolant spray compared to lidocaine/prilocaine cream in dogs and cats.Materials and MethodsA randomised controlled trial of client-owned dogs... Read More about Effectiveness of vapocoolant spray compared to eutectic lidocaine/prilocaine cream to enhance tolerance during intravenous catheterisation: a randomised controlled trial.

A new future for dog breeding (2025)
Journal Article
Proschowsky, H., Arendt, M., Bonnett, B., Bruun, C., Czycholl, I., Fredholm, M., O'Neill, D., Serpell, J., & Sandoe, P. (2025). A new future for dog breeding. Animal Welfare Journal, 34, https://doi.org/10.1017/awf.2024.66

The modern idea of purebred dogs has come under increasing critical scrutiny over recent decades. In light of this critical focus and other developments in society, some new trends in how companion dogs are bred and acquired have emerged. This means... Read More about A new future for dog breeding.

Early-life enrichment in American mink (Neogale vison): Effects of juvenile physical enrichment on behaviour, temperament, and long-term stereotypic behaviour (2025)
Journal Article
Clark, G., Díez-León, M., & Meagher, R. (2025). Early-life enrichment in American mink (Neogale vison): Effects of juvenile physical enrichment on behaviour, temperament, and long-term stereotypic behaviour. Animal Welfare Journal, 34, https://doi.org/10.1017/awf.2024.72

A single manipulable enrichment is often introduced to the pens of farmed American mink (Neogale vison) to combat stereotypic behaviour and behaviours or temperaments associated with poor welfare (e.g. inactivity, fear, and aggression). This enrichme... Read More about Early-life enrichment in American mink (Neogale vison): Effects of juvenile physical enrichment on behaviour, temperament, and long-term stereotypic behaviour.

Identification of a global gene expression signature associated with the genetic risk of catastrophic fracture in iPSC-derived osteoblasts from Thoroughbred horses (2025)
Journal Article
Palomino Lago, E., Ross, A., McClellan, A., & Guest, D. (2025). Identification of a global gene expression signature associated with the genetic risk of catastrophic fracture in iPSC-derived osteoblasts from Thoroughbred horses. Animal Genetics, https://doi.org/10.1111/age.13504

Bone fractures are a significant problem in Thoroughbred racehorses. The risk of fracture is influenced by both genetic and environmental factors. To determine the biological processes that are affected in genetically susceptible horses, we utilised... Read More about Identification of a global gene expression signature associated with the genetic risk of catastrophic fracture in iPSC-derived osteoblasts from Thoroughbred horses.

The microRNA-455 null mouse shows dysregulated bone turnover (2025)
Journal Article
Niu, L., Swingler, T., Suelzu, C., Ersek, A., Orriss, I., Barter, M., Hayman, D., Young, D., Horwood, N., & Clark, I. (2025). The microRNA-455 null mouse shows dysregulated bone turnover. JBMR Plus, 9(3), https://doi.org/10.1093/jbmrpl/ziaf007

A wide range of specific microRNAs have been shown to have either positive or negative effects on osteoblast differentiation and function, with consequent changes in postnatal bone mass. A number of specific targets have been identified. We previousl... Read More about The microRNA-455 null mouse shows dysregulated bone turnover.

Adjuvant Chemotherapy Is Associated With Prolonged Survival Time in Small-Breed Dogs Undergoing Amputation for Appendicular Osteosarcoma (2025)
Journal Article
Zanardi, S., Sabattini, S., Rossi, F., Rossanese, M., Buracco, P., Montinaro, V., Aralla, M., Dentini, A., Pizzi, E., Volpe, E., Tremolada, G., & Marconato, L. (2025). Adjuvant Chemotherapy Is Associated With Prolonged Survival Time in Small-Breed Dogs Undergoing Amputation for Appendicular Osteosarcoma. Veterinary and Comparative Oncology, https://doi.org/10.1111/vco.13041

Adjuvant chemotherapy is a well-established treatment for large-breed dogs with appendicular osteosarcoma; however, it is unclear if it improves outcomes in small-breed dogs due to limited focused studies. This retrospective study aimed to investigat... Read More about Adjuvant Chemotherapy Is Associated With Prolonged Survival Time in Small-Breed Dogs Undergoing Amputation for Appendicular Osteosarcoma.

Intracardiac lymphoma in a cat: Diagnosis and response to chemotherapy treatment (2025)
Journal Article
Lappalainen, M., Fuentes, V., Sargent, J., & Desmas-Bazelle, I. (2025). Intracardiac lymphoma in a cat: Diagnosis and response to chemotherapy treatment. Vet Record Case Reports, https://doi.org/10.1002/vrc2.1084

A three-year-old female cat presented for further investigations for pleural effusion following a short period of weight loss, lethargy and hyporexia. A computed tomography scan and echocardiography showed a right atrial wall mass, of which cytology... Read More about Intracardiac lymphoma in a cat: Diagnosis and response to chemotherapy treatment.