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A review of hyperfibrinolysis in cats and dogs (2019)
Journal Article
Birkbeck, R. N., Cortellini, S., & Humm, K. R. (2019). A review of hyperfibrinolysis in cats and dogs. Journal of Small Animal Practice, 60(11), 641-655. https://doi.org/10.1111/jsap.13068

The fibrinolytic system is activated concurrently with coagulation; it regulates haemostasis and prevents thrombosis by restricting clot formation to the area of vascular injury and dismantling the clot as healing occurs. Dysregulation of the fibrino... Read More about A review of hyperfibrinolysis in cats and dogs.

Preliminary insight into horse owners' perceptions of, and attitudes towards, exotic diseases in the United Kingdom (2019)
Journal Article
Spence, K. L., Cardwell, J. M., Slater, J. D., & Rosanowski, S. M. (2019). Preliminary insight into horse owners' perceptions of, and attitudes towards, exotic diseases in the United Kingdom. BMC Veterinary Research, 15(338), https://doi.org/10.1186/s12917-019-2120-5

The potential for an exotic disease incursion is a significant concern for the United Kingdom (UK) equine industry. Horse owners’ perceptions of, and attitudes towards, exotic diseases can influence decisions to adopt disease preparedness strategies.... Read More about Preliminary insight into horse owners' perceptions of, and attitudes towards, exotic diseases in the United Kingdom.

Long-term incidence and risk of noncardiovascular and all-cause mortality in apparently healthy cats and cats with preclinical hypertrophic cardiomyopathy (2019)
Journal Article
Fox, P. R., Keene, B. W., Lamb, K., Schober, K. E., Chetboul, V., Fuentes, V. L., …Yukie Tachika Ohara, V. (2019). Long-term incidence and risk of noncardiovascular and all-cause mortality in apparently healthy cats and cats with preclinical hypertrophic cardiomyopathy. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.15609

Juvenile-onset and adult-onset demodicosis in dogs in the UK: prevalence and breed associations (2019)
Journal Article
O'Neill, D. G., Turgoose, E., Church, D. B., Brodbelt, D. C., & Hendricks, A. (2019). Juvenile-onset and adult-onset demodicosis in dogs in the UK: prevalence and breed associations. Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13067

Objectives To explore epidemiological features of demodicosis relevant to UK veterinary general practitioners. Breed risk factors were proposed as distinct between juvenile‐onset and adult‐onset disease. Materials and Methods The study used anon... Read More about Juvenile-onset and adult-onset demodicosis in dogs in the UK: prevalence and breed associations.

A possible solution to model nonlinearity in elimination and distributional clearances with a2-adrenergic receptor agonists: Example of the intravenous detomidine and methadone combination in sedated horses (2019)
Journal Article
Gozalo-Marcilla, M., Moreira Da Silva, R., Pacca Loureiro Luna, S., Rodrigues De Oliveira, A., Werneck Fonseca, M., Peporine Lopes, N., …Pelligand, L. (2019). A possible solution to model nonlinearity in elimination and distributional clearances with a2-adrenergic receptor agonists: Example of the intravenous detomidine and methadone combination in sedated horses. Journal of Veterinary Pharmacology and Therapeutics, https://doi.org/10.1111/jvp.12815

Risk of intra-articular injection with longitudinal ultrasound-guided injection of the collateral ligaments of the distal interphalangeal joint in the horse (2019)
Journal Article
Smith, R. K. W., Parsons, J., & Dixon, J. J. (2019). Risk of intra-articular injection with longitudinal ultrasound-guided injection of the collateral ligaments of the distal interphalangeal joint in the horse. https://doi.org/10.1111/vru.12811

Desmopathy of the collateral ligaments of the distal interphalangeal joint is a common cause of equine foot lameness and carries a poor prognosis with conservative management. Intralesional injections may improve healing, although accuracy of radiogr... Read More about Risk of intra-articular injection with longitudinal ultrasound-guided injection of the collateral ligaments of the distal interphalangeal joint in the horse.

Phenotypic characterisation of regulatory T cells in dogs reveals signature transcripts conserved in humans and mice (2019)
Journal Article
Ying Wu, , Chang, Y. M., Stell, A. J., Priestnall, S. L., Sharma, E., Goulart, M. R., …Garden, O. A. (2019). Phenotypic characterisation of regulatory T cells in dogs reveals signature transcripts conserved in humans and mice. https://doi.org/10.1038/s41598-019-50065-8

Regulatory T cells (Tregs) are a double-edged regulator of the immune system. Aberrations of Tregs correlate with pathogenesis of inflammatory, autoimmune and neoplastic disorders. Phenotypically and functionally distinct subsets of Tregs have been i... Read More about Phenotypic characterisation of regulatory T cells in dogs reveals signature transcripts conserved in humans and mice.

Persian cats under first opinion veterinary care in the UK: demography, mortality and disorders (2019)
Journal Article
O'Neill, D. G., Romans, C., Brodbelt, D. C., Church, D. B., Cerna, P., & Gunn-Moore, D. A. (2019). Persian cats under first opinion veterinary care in the UK: demography, mortality and disorders. https://doi.org/10.1038/s41598-019-49317-4

Persian cats are a popular cat breed worldwide, and especially in the US, Europe and Asia. This study aimed to describe the demography, common disorders and mortality in Persians under general practice veterinary care in 2013 in the UK. The study pop... Read More about Persian cats under first opinion veterinary care in the UK: demography, mortality and disorders.

A multi-centre cohort study investigating the outcome of synovial contamination or sepsis of the calcaneal bursae in horses treated by endoscopic lavage and debridement (2019)
Journal Article
Isgren, C. M., Salem, S. E., Singer, E. R., Wylie, C. E., Lipreri, G., Graham, R. J. T. Y., …Rubio-Martínez, L. M. (2019). A multi-centre cohort study investigating the outcome of synovial contamination or sepsis of the calcaneal bursae in horses treated by endoscopic lavage and debridement. Equine Veterinary Journal, 52(3), 404-410. https://doi.org/10.1111/evj.13180

Assessing pathological changes within the nucleus ambiguus of horses with Recurrent Laryngeal Neuropathy: an extreme, length-dependent axonopathy (2019)
Journal Article
Draper, A. C. E., Cahalan, S. D., Goodwin, D., Perkins, J. D. M., & Piercy, R. J. (2019). Assessing pathological changes within the nucleus ambiguus of horses with Recurrent Laryngeal Neuropathy: an extreme, length-dependent axonopathy. Muscle & Nerve, https://doi.org/10.1002/mus.26699

Equine recurrent laryngeal neuropathy (RLN) is a naturally occurring model of length‐dependent axonopathy characterised by asymmetrical degeneration of recurrent laryngeal nerve axons (RLn). Distal RLn degeneration is marked, however it is unclear wh... Read More about Assessing pathological changes within the nucleus ambiguus of horses with Recurrent Laryngeal Neuropathy: an extreme, length-dependent axonopathy.

Inducing pluripotency in the domestic cat (Felis Catus) (2019)
Journal Article
Dutton, L. C., Dudhia, J., Guest, D. J., & Connolly, D. J. (2019). Inducing pluripotency in the domestic cat (Felis Catus). Stem Cells and Development, 28(19), 1299-1309. https://doi.org/10.1089/scd.2019.0142

Domestic cats suffer from a range of inherited genetic diseases, many of which display similarities with equivalent human conditions. Developing cellular models for these inherited diseases would enable drug discovery, benefiting feline health and we... Read More about Inducing pluripotency in the domestic cat (Felis Catus).

West Highland White Terriers under primary veterinary care in the UK in 2016: demography, mortality and disorders (2019)
Journal Article
O'Neill, D. G., Ballantyne, Z. F., Hendricks, A., Church, D. B., Brodbelt, D. C., & Pegram, C. L. (2019). West Highland White Terriers under primary veterinary care in the UK in 2016: demography, mortality and disorders. Canine Genetics and Epidemiology, 6, https://doi.org/10.1186/s40575-019-0075-2

The West Highland White Terrier (WHWT) is a relatively common breed in the UK, although Kennel Club registrations have declined in recent years. The VetCompass™ Programme collates de-identified clinical data from primary-care veterinary practices in... Read More about West Highland White Terriers under primary veterinary care in the UK in 2016: demography, mortality and disorders.