A fusion of minicircle DNA and nanoparticle delivery technologies facilitates therapeutic genetic engineering of autologous canine olfactory mucosal cells
(2017)
Journal Article
Delaney, A. M., Adams, C. F., Fernandes, A. R., Al-Shakli, A. F., Sen, J., Carwardine, D. R., Granger, N., & Chari, D. M. (2017). A fusion of minicircle DNA and nanoparticle delivery technologies facilitates therapeutic genetic engineering of autologous canine olfactory mucosal cells. Nanoscale, 9(25), 8560-8566. https://doi.org/10.1039/c7nr00811b
Olfactory ensheathing cells (OECs) promote axonal regeneration and improve locomotor function when transplanted into the injured spinal cord. A recent clinical trial demonstrated improved motor function in domestic dogs with spinal injury following a... Read More about A fusion of minicircle DNA and nanoparticle delivery technologies facilitates therapeutic genetic engineering of autologous canine olfactory mucosal cells.