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All Outputs (16)

Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation (2020)
Journal Article
Wu, Y., Chang, Y. M., Polton, G., Stell, A. J., Szladovits, B., Macfarlane, M., …Garden, O. A. (2020). Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation. Frontiers in Oncology, 10, https://doi.org/10.3389/fonc.2020.00307

Gene expression profiling has revealed molecular heterogeneity of diffuse large B cell lymphoma (DLBCL) in both humans and dogs. Two DLBCL subtypes based on cell of origin are generally recognized, germinal center B (GCB)-like and activated B cell (A... Read More about Gene Expression Profiling of B Cell Lymphoma in Dogs Reveals Dichotomous Metabolic Signatures Distinguished by Oxidative Phosphorylation.

Abdominal CT evaluation of the liver and spleen for staging mast cell tumors in dogs yields nonspecific results (2019)
Journal Article
Hughes, J. R., Szladovits, B., & Drees, R. (2019). Abdominal CT evaluation of the liver and spleen for staging mast cell tumors in dogs yields nonspecific results. https://doi.org/10.1111/vru.12717

Canine mast cell tumor staging is commonly performed using abdominal ultrasonography and fine‐needle aspiration cytology of masses, lymph nodes, and hepatic and splenic parenchyma. Computed tomography is used for abdominal, thoracic, or whole body im... Read More about Abdominal CT evaluation of the liver and spleen for staging mast cell tumors in dogs yields nonspecific results.

Aldosterone-producing adrenocortical carcinoma with myxoid differentiation in a cat (2018)
Journal Article
Attipa, C., Beck, S., Lipscomb, V. J., English, K., Carvalho, S., Kiupel, M., …Peters, L. M. (2018). Aldosterone-producing adrenocortical carcinoma with myxoid differentiation in a cat. Veterinary Clinical Pathology, 47(4), 660-664. https://doi.org/10.1111/vcp.12658

A 10‐year‐old male neutered Persian cat was presented with an abdominal mass and history of weakness. Blood smear examination found marked elliptocytosis, and serum biochemical analysis revealed hypokalemia, hypochloremia, increased creatine kinase a... Read More about Aldosterone-producing adrenocortical carcinoma with myxoid differentiation in a cat.

Diagnosis of anaplastic large-cell lymphoma in a dog using CD30 immunohistochemistry (2018)
Journal Article
Pittaway, R., Wu, Y., Suárez-Bonnet, A., Szladovits, B., Scurrell, E. J., Garden, O. A., …Priestnall, S. L. (2018). Diagnosis of anaplastic large-cell lymphoma in a dog using CD30 immunohistochemistry. Journal of Veterinary Diagnostic Investigation, https://doi.org/10.1177/1040638718760965

Anaplastic large-cell lymphoma or null-cell lymphoma is a clinical entity reported in people, classified according to the unique appearance of large pleomorphic cells that express CD30. Null-cell lymphoma has also been described in dogs when neither... Read More about Diagnosis of anaplastic large-cell lymphoma in a dog using CD30 immunohistochemistry.

Feline primary erythrocytosis: a multicentre case series of 18 cats (2018)
Journal Article
Darcy, H., Simpson, K., Gajanayake, I., Seth, M., McGrotty, Y., Szladovits, B., & Glanemann, B. (2018). Feline primary erythrocytosis: a multicentre case series of 18 cats. Journal of Feline Medicine and Surgery, https://doi.org/10.1177/1098612X17750333

A retrospective multicentre case series of feline primary erythrocytosis (PE) was evaluated. The aim was to gain better understanding of disease presentation and progression to guide management and prognostication. Case records were assessed for evid... Read More about Feline primary erythrocytosis: a multicentre case series of 18 cats.

Serum Biochemical Phenotypes in the Domestic Dog (2016)
Journal Article
Chang, Y. M., Hadox, E., Szladovits, B., & Garden, O. A. (2016). Serum Biochemical Phenotypes in the Domestic Dog. PLoS ONE, 11(2), e0149650. https://doi.org/10.1371/journal.pone.0149650

The serum or plasma biochemical profile is essential in the diagnosis and monitoring of systemic disease in veterinary medicine, but current reference intervals typically take no account of breed-specific differences. Breed-specific hematological phe... Read More about Serum Biochemical Phenotypes in the Domestic Dog.

Dissecting the Regulatory Microenvironment of a Large Animal Model of Non-Hodgkin Lymphoma: Evidence of a Negative Prognostic Impact of FOXP3+ T Cells in Canine B Cell Lymphoma (2014)
Journal Article
Pinheiro, D. Y., Chang, Y. M., Bryant, H., Szladovits, B., Dalessandri, T., Davison, L. J., …Garden, O. A. (2014). Dissecting the Regulatory Microenvironment of a Large Animal Model of Non-Hodgkin Lymphoma: Evidence of a Negative Prognostic Impact of FOXP3+ T Cells in Canine B Cell Lymphoma. PLoS ONE, 9(8), e105027. https://doi.org/10.1371/journal.pone.0105027

The cancer microenvironment plays a pivotal role in oncogenesis, containing a number of regulatory cells that attenuate the anti-neoplastic immune response. While the negative prognostic impact of regulatory T cells (Tregs) in the context of most sol... Read More about Dissecting the Regulatory Microenvironment of a Large Animal Model of Non-Hodgkin Lymphoma: Evidence of a Negative Prognostic Impact of FOXP3+ T Cells in Canine B Cell Lymphoma.

Evaluation of concurrent analysis of cerebrospinal fluid samples collected from the cerebellomedullary cistern and lumbar subarachnoid space for the diagnosis of steroid-responsive meningitis arteritis in dogs
Journal Article
Carletti, B. E., De Decker, S., Rose, J., Sanchez-Masian, D., Bersan, E., Cooper, C., …Gonçalves, R. Evaluation of concurrent analysis of cerebrospinal fluid samples collected from the cerebellomedullary cistern and lumbar subarachnoid space for the diagnosis of steroid-responsive meningitis arteritis in dogs. Journal of the American Veterinary Medical Association, 255, 1035-1038. https://doi.org/10.2460/javma.255.9.1035