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An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of a-synuclein
Report
Kara, E., Crimi, A., Wiedmer, A., Emmenegger, M., Manzoni, C., Bandres-Ciga, S., D’Sa, K., Reynolds, R., Botía, J., Losa, M., Lysenko, V., Carta, M., Heinzer, D., Avar, M., Chincisan, A., Blauwendraat, C., Ruiz, S., Pease, D., Mottier, L., Carrella, A., …Aguzzi, A. An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of a-synuclein

Neuropathological and experimental evidence suggests that the cell-to-cell transfer of a-synuclein has an important role in the pathogenesis of Parkinson’s disease (PD). However, the mechanism underlying this phenomenon is not fully understood. We un... Read More about An integrated genomic approach to dissect the genetic landscape regulating the cell-to-cell transfer of a-synuclein.

Mutations in Auxilin cause parkinsonism via impaired clathrin-mediated trafficking at the Golgi apparatus and synapse
Report
Roosen, D., Landeck, N., Conti, M., Smith, N., Saez-Atienzar, S., Ding, J., Beilina, A., Kumaran, R., Kaganovich, A., Hoffmann, J., Williamson, C., Gershlick, D., Bonet-Ponce, L., Sampieri, L., Bleck, C., Liu, C., Bonifacino, J., Li, Y., Lewis, P., & Cookson, M. Mutations in Auxilin cause parkinsonism via impaired clathrin-mediated trafficking at the Golgi apparatus and synapse

Parkinson’s disease (PD) is a common neurodegenerative motor disorder characterized in part by neuropathological lesions in the nigrostriatal pathway. While most cases of PD are sporadic in nature, several inherited monogenic syndromes exist that ove... Read More about Mutations in Auxilin cause parkinsonism via impaired clathrin-mediated trafficking at the Golgi apparatus and synapse.

Veterinary homeopathy regulation in the UK – a cause for concern
Journal Article
Whitehead, M. L., Lees, P., & Toutain, P. L. Veterinary homeopathy regulation in the UK – a cause for concern

Practitioners of homeopathy claim to treat illness by
manipulation of an undetectable healing force or energy. The Veterinary Medicines Regulations 2013 allow homeopathic products to be registered without proof of therapeutic efficacy, as required b... Read More about Veterinary homeopathy regulation in the UK – a cause for concern.