Reply to: Letter to the Editor from Malik et al: Acute kidney injury following subcutaneous meloxicam administration
(2024)
Journal Article
Pelligand, L., King, J., Stapleton, N., D'Arcy-Howard, D., Elliott, J., & Krekis, A. (in press). Reply to: Letter to the Editor from Malik et al: Acute kidney injury following subcutaneous meloxicam administration. Journal of Veterinary Pharmacology and Therapeutics, https://doi.org/10.1111/jvp.13438
All Outputs (5)
Control of a sulfadoxine/trimethoprim combination in the competition horse: Elimination, metabolism and detection following an intravenous administration (2023)
Journal Article
Schenk, I., Broussou, D., Roques, B., Lagershausen, H., Machnik, M., Röttgen, H., …Thevis, M. (2023). Control of a sulfadoxine/trimethoprim combination in the competition horse: Elimination, metabolism and detection following an intravenous administration. Drug Testing and Analysis, https://doi.org/10.1002/dta.3461
Doxycycline serum protein binding in pigs reveals a relatively high free fraction (2023)
Journal Article
Felipe Ramon, P., Marlène Z., L., Béatrice B., R., Véronique, G., Pierre-Louis, T., & Bousquet-Mélou, A. (2023). Doxycycline serum protein binding in pigs reveals a relatively high free fraction. Journal of Veterinary Pharmacology and Therapeutics, https://doi.org/10.1111/jvp.13111Doxycycline is an antibiotic widely used in pig farming, which leads to update the doses using PK/PD concepts. However, there is an impasse to estimate the PK/PD cut-off of doxycycline in pigs. Indeed, considering its 7% free fraction and the total s... Read More about Doxycycline serum protein binding in pigs reveals a relatively high free fraction.
Rational determination of cefazolin dosage regimen in horses based on pharmacokinetics/pharmacodynamics principles and Monte Carlo simulations (2022)
Journal Article
Kuroda, T., Minamijima, Y., Mita, H., Tamura, N., Fukuda, K., Kuwano, A., …Sato, F. (2022). Rational determination of cefazolin dosage regimen in horses based on pharmacokinetics/pharmacodynamics principles and Monte Carlo simulations. Journal of Veterinary Pharmacology and Therapeutics, https://doi.org/10.1111/jvp.13099A pharmacokinetics/pharmacodynamics (PK/PD) approach was used to determine
the best empirical dosage regimen of cefazolin (CEZ) after intramuscular (IM) administration
of CEZ in horses. Seven horses received a single IM or intravenous (IV) administ... Read More about Rational determination of cefazolin dosage regimen in horses based on pharmacokinetics/pharmacodynamics principles and Monte Carlo simulations.
A Large Impact of Obesity on the Disposition of Ivermectin, Moxidectin and Eprinomectin in a Canine Model: Relevance for COVID-19 Patients (2021)
Journal Article
Bousquet-Mélou, A., Lespine, A., Sutra, J., Bargues, I., & Toutain, P. (2021). A Large Impact of Obesity on the Disposition of Ivermectin, Moxidectin and Eprinomectin in a Canine Model: Relevance for COVID-19 Patients. Frontiers in Pharmacology, https://doi.org/10.3389/fphar.2021.666348Ivermectin (IVM) and moxidectin (MOX) are used extensively as parasiticides in veterinary medicine. Based on in vitro data, IVM has recently been proposed for the prevention and treatment of COVID-19 infection, a condition for which obesity is a majo... Read More about A Large Impact of Obesity on the Disposition of Ivermectin, Moxidectin and Eprinomectin in a Canine Model: Relevance for COVID-19 Patients.