Frequency and risk factors for naturally occurring Cushing's syndrome in dogs attending UK primary-care practices
(2021)
Journal Article
Schofield, I., Brodbelt, D., Niessen, S., Church, D., Geddes, R., & O'Neill, D. (2022). Frequency and risk factors for naturally occurring Cushing's syndrome in dogs attending UK primary-care practices. Journal of Small Animal Practice, 63(4), 265-274. https://doi.org/10.1111/jsap.13450
All Outputs (210)
A genome-wide association study identifies novel candidate genes for susceptibility to diabetes mellitus in non-obese cats (2021)
Journal Article
Catchpole, B., Forcada, Y., Boursnell, M., & Church, D. (2021). A genome-wide association study identifies novel candidate genes for susceptibility to diabetes mellitus in non-obese cats. PLoS ONE, https://doi.org/10.1371/journal.pone.0259939Diabetes mellitus (DM) is a common feline endocrinopathy, which is similar to human type 2 diabetes (T2DM) in terms of its pathophysiology. T2DM occurs due to peripheral insulin resistance and/or β-cell dysfunction. Several studies have identified ge... Read More about A genome-wide association study identifies novel candidate genes for susceptibility to diabetes mellitus in non-obese cats.
French Bulldogs differ to other dogs in the UK in propensity for many common disorders: a VetCompass study (2021)
Journal Article
O'Neill, D., Packer, R., Francis, P., Church, D., Brodbelt, D., & Pegram, C. (2021). French Bulldogs differ to other dogs in the UK in propensity for many common disorders: a VetCompass study. Canine Medicine and Genetics, 8(1), 13. https://doi.org/10.1186/s40575-021-00112-3
Frequency, breed predisposition and demographic risk factors for overweight status in dogs in the UK (2021)
Journal Article
Pegram, C., Raffan, E., White, E., Ashworth, A., Brodbelt, D., Church, D., & O'Neill, D. (2021). Frequency, breed predisposition and demographic risk factors for overweight status in dogs in the UK. Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13325Objectives: To evaluate the prevalence and risk factors for overweight status in dogs under primary veterinary care in the UK. Methods: A retrospective study design was used to estimate the one-year (2016) period prevalence of overweight status. The... Read More about Frequency, breed predisposition and demographic risk factors for overweight status in dogs in the UK.
Efficacy of hypophysectomy for the treatment of hypersomatotropism‐induced diabetes mellitus in 68 cats (2021)
Journal Article
Fenn, J., Kenny, P. J., Scudder, C. J., Hazuchova, K., Gostelow, R., Fowkes, R. C., …Niessen, S. J. M. (in press). Efficacy of hypophysectomy for the treatment of hypersomatotropism‐induced diabetes mellitus in 68 cats. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16080
Natriuretic peptide expression and function in GH3 somatolactotropes and feline somatotrope pituitary tumors (2021)
Journal Article
Mirczuk, S., Scudder, C., Read, J., Crossley, V., Regan, J., Richardson, K., …Fowkes, R. (2021). Natriuretic peptide expression and function in GH3 somatolactotropes and feline somatotrope pituitary tumors. International Journal of Molecular Sciences, -. https://doi.org/10.3390/ijms22031076Patients harbouring mutations in genes encoding C-type natriuretic peptide (CNP; NPPC) or its receptor guanylyl cyclase B (GC-B, NPR2) suffer from severe growth phenotypes; loss-of-function mutations cause achondroplasia, whereas gain-of-function mut... Read More about Natriuretic peptide expression and function in GH3 somatolactotropes and feline somatotrope pituitary tumors.
Hypoadrenocorticism in dogs under UK primary veterinary care: frequency, clinical approaches and risk factors (2020)
Journal Article
Schofield, I., Woolhead, V., Johnson, A., Brodbelt, D. C., Church, D. B., & O'Neill, D. G. (2020). Hypoadrenocorticism in dogs under UK primary veterinary care: frequency, clinical approaches and risk factors. Journal of Small Animal Practice, 1-8. https://doi.org/10.1111/jsap.13285Objectives: To estimate the frequency, clinical approaches and risk factors of hypoadrenocorticism in dogs under UK primary veterinary care. Materials and MethOds: Dogs diagnosed with hypoadrenocorticism were identified from the UK VetCompass™ progr... Read More about Hypoadrenocorticism in dogs under UK primary veterinary care: frequency, clinical approaches and risk factors.
Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management (2020)
Journal Article
Radulescu, S. M., Humm, K., Eramanis, L. M., Volk, H. A., Church, D. B., Brodbelt, D., & O'Neill, D. G. (2020). Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.15869Background Vestibular disease (VD), central or peripheral, can be a dramatic primary‐care presentation. Current literature describes mostly dogs examined in referral centers. Hypothesis/Objectives Describe the prevalence, presentation, clini... Read More about Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management.
Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management (2020)
Journal Article
Radulescu, S. M., Humm, K., Eramanis, L. M., Volk, H. A., Church, D. B., Brodbelt, D., & O'Neill, D. G. (2020). Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management. Journal of Veterinary Internal Medicine, 34(5), 1993-2004. https://doi.org/10.1111/jvim.15869Background Vestibular disease (VD), central or peripheral, can be a dramatic primary‐care presentation. Current literature describes mostly dogs examined in referral centers. Hypothesis/Objectives Describe the prevalence, presentation, clini... Read More about Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management.
Clinical management of lipomas in dogs under primary care in the UK (2020)
Journal Article
Pegram, C. L., Rutherford, L., Corah, C., Church, D. B., Brodbelt, D. C., & O'Neill, D. G. (2020). Clinical management of lipomas in dogs under primary care in the UK. Veterinary Record, vetrec-2019Lipomas are relatively common and biologically benign masses of mesenchymal origin consisting of adipocytes. This study reports benchmark data on the clinical management and outcomes of lipomas in dogs under UK primary veterinary care. The study used... Read More about Clinical management of lipomas in dogs under primary care in the UK.
Diabetes mellitus in dogs attending UK primary-care practices: frequency, risk factors and survival (2020)
Journal Article
Heeley, A., O’Neill, D., Davison, L., Church, D., Corless, E., & Brodbelt, D. (2020). Diabetes mellitus in dogs attending UK primary-care practices: frequency, risk factors and survival. Canine Medicine and Genetics, 7(1), https://doi.org/10.1186/s40575-020-00087-7Background: Diabetes mellitus (DM) is an important endocrine disorder of dogs. The objectives of this study were to estimate prevalence and incidence of DM in dogs, and to explore risk factors for DM and the survival of DM cases in primary-care clini... Read More about Diabetes mellitus in dogs attending UK primary-care practices: frequency, risk factors and survival.
Epidemiology and clinical management of elbow joint disease in dogs under primary veterinary care in the UK (2020)
Journal Article
O'Neill, D. G., Brodbelt, D. C., Hodge, R., Church, D. B., & Meeson, R. L. (2020). Epidemiology and clinical management of elbow joint disease in dogs under primary veterinary care in the UK. https://doi.org/10.1186/s40575-020-0080-5Conditions affecting the elbow joint are a common cause of lameness in dogs. Primary-care veterinary clinical data are now recognised as a valuable research resource. Using data from the VetCompass Programme, this study aimed to report the frequency... Read More about Epidemiology and clinical management of elbow joint disease in dogs under primary veterinary care in the UK.
Demography and commonly recorded clinical conditions of Chihuahuas under primary veterinary care in the UK in 2016 (2020)
Journal Article
O’Neill, D. G., Packer, R. M. A., Lobb, M., Church, D. B., Brodbelt, D. C., & Pegram, C. (2020). Demography and commonly recorded clinical conditions of Chihuahuas under primary veterinary care in the UK in 2016. BMC Veterinary Research, 16(42), https://doi.org/10.1186/s12917-020-2258-1The Chihuahua, the world’s smallest dog breed, is a popular breed in the UK today. The VetCompass™ Programme collates de-identified clinical records from primary-care veterinary practices in the UK for epidemiological research. This study aimed to ch... Read More about Demography and commonly recorded clinical conditions of Chihuahuas under primary veterinary care in the UK in 2016.
Development and evaluation of a health-related quality-of-life tool for dogs with Cushing's syndrome (2019)
Journal Article
Schofield, I., O'Neill, D. G., Brodbelt, D. C., Church, D. B., Geddes, R. F., & Niessen, S. J. M. (2019). Development and evaluation of a health-related quality-of-life tool for dogs with Cushing's syndrome. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.15639
Morbidity and mortality of domestic rabbits (Oryctolagus cuniculus) under primary veterinary care in England (2019)
Journal Article
O'Neill, D. G., Craven, H. C., Brodbelt, D. C., Church, D. B., & Hedley, J. (2019). Morbidity and mortality of domestic rabbits (Oryctolagus cuniculus) under primary veterinary care in England. Veterinary Record, https://doi.org/10.1136/vr.105592
Juvenile-onset and adult-onset demodicosis in dogs in the UK: prevalence and breed associations (2019)
Journal Article
O'Neill, D. G., Turgoose, E., Church, D. B., Brodbelt, D. C., & Hendricks, A. (2019). Juvenile-onset and adult-onset demodicosis in dogs in the UK: prevalence and breed associations. Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13067Objectives To explore epidemiological features of demodicosis relevant to UK veterinary general practitioners. Breed risk factors were proposed as distinct between juvenile‐onset and adult‐onset disease. Materials and Methods The study used anon... Read More about Juvenile-onset and adult-onset demodicosis in dogs in the UK: prevalence and breed associations.
Persian cats under first opinion veterinary care in the UK: demography, mortality and disorders (2019)
Journal Article
O'Neill, D. G., Romans, C., Brodbelt, D. C., Church, D. B., Cerna, P., & Gunn-Moore, D. A. (2019). Persian cats under first opinion veterinary care in the UK: demography, mortality and disorders. https://doi.org/10.1038/s41598-019-49317-4Persian cats are a popular cat breed worldwide, and especially in the US, Europe and Asia. This study aimed to describe the demography, common disorders and mortality in Persians under general practice veterinary care in 2013 in the UK. The study pop... Read More about Persian cats under first opinion veterinary care in the UK: demography, mortality and disorders.
West Highland White Terriers under primary veterinary care in the UK in 2016: demography, mortality and disorders (2019)
Journal Article
O'Neill, D. G., Ballantyne, Z. F., Hendricks, A., Church, D. B., Brodbelt, D. C., & Pegram, C. L. (2019). West Highland White Terriers under primary veterinary care in the UK in 2016: demography, mortality and disorders. Canine Genetics and Epidemiology, 6, https://doi.org/10.1186/s40575-019-0075-2The West Highland White Terrier (WHWT) is a relatively common breed in the UK, although Kennel Club registrations have declined in recent years. The VetCompass™ Programme collates de-identified clinical data from primary-care veterinary practices in... Read More about West Highland White Terriers under primary veterinary care in the UK in 2016: demography, mortality and disorders.
Disorders of Bulldogs under primary veterinary care in the UK in 2013 (2019)
Journal Article
O'Neill, D. G., Skipper, A. M., Kadhim, J., Church, D. B., Brodbelt, D. C., & Packer, R. M. A. (2019). Disorders of Bulldogs under primary veterinary care in the UK in 2013. PLoS ONE, 14(6), e0217928. https://doi.org/10.1371/journal.pone.0217928The Bulldog is a popular companion breed in the UK despite widely reported disease predispositions. This study aimed to characterise the demography, mortality and common disorders of Bulldogs under veterinary care in the UK during 2013. VetCompass co... Read More about Disorders of Bulldogs under primary veterinary care in the UK in 2013.
Systemic glucocorticoid usage in dogs under primary veterinary care in the UK: prevalence and risk factors (2019)
Journal Article
Elkholly, D. A., O'Neill, D. G., Wright, A. K., Mwacalimba, K., Nolan, L. S., Pavlock, A., …Brodbelt, D. C. (2019). Systemic glucocorticoid usage in dogs under primary veterinary care in the UK: prevalence and risk factors. Veterinary Record, 185(4), https://doi.org/10.1136/vr.105220