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All Outputs (214)

Agreeing Language in Veterinary Endocrinology (ALIVE): Diabetes mellitus - a modified Delphi-method-based system to create consensus disease definitions (2022)
Journal Article
ESVE SCE Membership, Niessen, S., Bjornvad, C., Church, D., Davison, L., Esteban-Saltiveri, D., Fleeman, L., Forcada, Y., Fracassi, F., Gilor, C., Hanson, J., Herrtage, M., Lathan, P., Leal, R., Loste, A., Reusch, C., Schermerhorn, T., Stengel, C., Thoresen, S., & Thuroczy, J. (2022). Agreeing Language in Veterinary Endocrinology (ALIVE): Diabetes mellitus - a modified Delphi-method-based system to create consensus disease definitions. The Veterinary Journal, 289, https://doi.org/10.1016/j.tvjl.2022.105910

English Bulldogs in the UK: a VetCompass study of their disorder predispositions and protections (2022)
Journal Article
O’Neill, D. G., Skipper, A., Packer, R. M. A., Lacey, C., Church, D. B., Brodbelt, D. C., & Pegram, C. (2022). English Bulldogs in the UK: a VetCompass study of their disorder predispositions and protections. Canine Medicine and Genetics, 9(1), https://doi.org/10.1186/s40575-022-00118-5

Background
The English Bulldog has risen sharply in popularity over the past decade but its distinctive and extreme conformation is linked to several serious health conditions. Using multivariable analysis of anonymised veterinary clinical data from... Read More about English Bulldogs in the UK: a VetCompass study of their disorder predispositions and protections.

Life tables of annual life expectancy and mortality for companion dogs in the United Kingdom (2022)
Journal Article
Tzu-yun Teng, K., Brodbelt, D., Pegram, C., Church, D., & O’Neill, D. (2022). Life tables of annual life expectancy and mortality for companion dogs in the United Kingdom. Scientific Reports, 12(1), 6415. https://doi.org/10.1038/s41598-022-10341-6

A life table is a tabulated expression of life expectancy and mortality-related information at specified ages in a given population. This study applied the VetCompass Programme to generate life tables for the UK dog population both overall and broken... Read More about Life tables of annual life expectancy and mortality for companion dogs in the United Kingdom.

Occurrence and clinical management of urethral obstruction in male cats under primary veterinary care in the United Kingdom in 2016 (2022)
Journal Article
Beeston, D., Humm, K., Church, D. B., Brodbelt, D., & O'Neill, D. G. (in press). Occurrence and clinical management of urethral obstruction in male cats under primary veterinary care in the United Kingdom in 2016. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16389

Background: Urethral obstruction (UO) has a negative effect on welfare of cats.

Objectives: This study aimed to determine incidence, case management, and outcomes of UO in cats in primary-care practice in the United Kingdom.

Animals: All male c... Read More about Occurrence and clinical management of urethral obstruction in male cats under primary veterinary care in the United Kingdom in 2016.

Breed and conformational predispositions for prolapsed nictitating membrane gland (PNMG) in dogs in the UK: A VetCompass study (2022)
Journal Article
O'Neill, D., Yahui, Y., Yin, Y., Pont, R., Brodbelt, D., Church, D., Pegram, C., Minn, M., & Mustikka, M. (2022). Breed and conformational predispositions for prolapsed nictitating membrane gland (PNMG) in dogs in the UK: A VetCompass study. PLoS ONE, 17(1), https://doi.org/10.1371/journal.pone.0260538

Background Prolapsed nictitating membrane gland (PNMG) is the most common disorder of the third eyelid in dogs. However, the epidemiology of PNMG in the wider dog population remains understudied. Methods Using de-identified clinical data from the Vet... Read More about Breed and conformational predispositions for prolapsed nictitating membrane gland (PNMG) in dogs in the UK: A VetCompass study.

Veterinary drug therapies used for undesirable behaviours in UK dogs under primary veterinary care (2022)
Journal Article
Pegram, C., Craven, A., Packer, R., Jarvis, S., McGreevy, P., Warnes, C., Church, D., Brodbelt, D., & O'Neill, D. (in press). Veterinary drug therapies used for undesirable behaviours in UK dogs under primary veterinary care. PLoS ONE, 17, https://doi.org/10.1371/journal.pone.0261139

Undesirable behaviours (UBs) in dogs are common and important issues with serious potential welfare consequences for both the dogs and their owners. This study aimed to investigate the usage of drug therapy for UBs in dogs and assess demographic risk... Read More about Veterinary drug therapies used for undesirable behaviours in UK dogs under primary veterinary care.

Disorder predispositions and protections of Labrador Retrievers in the UK (2021)
Journal Article
Pegram, C., Woolley, C., Brodbelt, D., Church, D., & O'Neill, D. (2021). Disorder predispositions and protections of Labrador Retrievers in the UK. Scientific Reports, 11(1), https://doi.org/10.1038/s41598-021-93379-2

The Labrador Retriever is one of the most popular dog breeds worldwide, therefore it is important to have reliable evidence on the general health issues of the breed. Using anonymised veterinary clinical data from the VetCompass Programme, this study... Read More about Disorder predispositions and protections of Labrador Retrievers in the UK.

A genome-wide association study identifies novel candidate genes for susceptibility to diabetes mellitus in non-obese cats (2021)
Journal Article
Catchpole, B., Forcada, Y., Boursnell, M., & Church, D. (2021). A genome-wide association study identifies novel candidate genes for susceptibility to diabetes mellitus in non-obese cats. PLoS ONE, https://doi.org/10.1371/journal.pone.0259939

Diabetes mellitus (DM) is a common feline endocrinopathy, which is similar to human type 2 diabetes (T2DM) in terms of its pathophysiology. T2DM occurs due to peripheral insulin resistance and/or β-cell dysfunction. Several studies have identified ge... Read More about A genome-wide association study identifies novel candidate genes for susceptibility to diabetes mellitus in non-obese cats.

Machine-learning based prediction of Cushing’s syndrome in dogs attending UK primary-care veterinary practice (2021)
Journal Article
Schofield, I., Brodbelt, D. C., Kennedy, N., Niessen, S. J. M., Church, D. B., Geddes, R. F., & O’Neill, D. G. (2021). Machine-learning based prediction of Cushing’s syndrome in dogs attending UK primary-care veterinary practice. Scientific Reports, 11(1), https://doi.org/10.1038/s41598-021-88440-z

Cushing’s syndrome is an endocrine disease in dogs that negatively impacts upon the quality-of-life of affected animals. Cushing’s syndrome can be a challenging diagnosis to confirm, therefore new methods to aid diagnosis are warranted. Four machine-... Read More about Machine-learning based prediction of Cushing’s syndrome in dogs attending UK primary-care veterinary practice.

Frequency, breed predisposition and demographic risk factors for overweight status in dogs in the UK (2021)
Journal Article
Pegram, C., Raffan, E., White, E., Ashworth, A., Brodbelt, D., Church, D., & O'Neill, D. (2021). Frequency, breed predisposition and demographic risk factors for overweight status in dogs in the UK. Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13325

Objectives: To evaluate the prevalence and risk factors for overweight status in dogs under primary veterinary care in the UK.
Methods: A retrospective study design was used to estimate the one-year (2016) period prevalence of overweight status. The... Read More about Frequency, breed predisposition and demographic risk factors for overweight status in dogs in the UK.

Increased insulin-like growth factor 1 concentrations in a retrospective population of non-diabetic cats diagnosed with hypertrophic cardiomyopathy (2021)
Journal Article
Steele, M. M., Borgeat, K., Payne, J. R., Coss, P., Navarro-Cubas, X., Church, D. B., Niessen, S. J., & Connolly, D. J. (in press). Increased insulin-like growth factor 1 concentrations in a retrospective population of non-diabetic cats diagnosed with hypertrophic cardiomyopathy. Journal of Feline Medicine and Surgery, 1098612X2098799. https://doi.org/10.1177/1098612x20987995