All Outputs (9987)

Pharmacological and Genetic Disruption of C-Type Natriuretic Peptide (nppcl) Expression in Zebrafish (Danio rerio) Causes Stunted Growth during Development (2023)
Journal Article
Lessey, A. J., Mirczuk, S. M., Chand, A. N., Kurrasch, D. M., Korbonits, M., Niessen, S. J. M., …Fowkes, R. C. (2023). Pharmacological and Genetic Disruption of C-Type Natriuretic Peptide (nppcl) Expression in Zebrafish (Danio rerio) Causes Stunted Growth during Development. International Journal of Molecular Sciences, 24(16), 12921. https://doi.org/10.3390/ijms241612921

Abstract Human patients with mutations within NPPC or NPR2 genes (encoding C-type natriuretic peptide (CNP) and guanylyl cyclase-B (GC-B), respectively) display clinical signs associated with skeletal abnormalities, such as overgrowth or short statu... Read More about Pharmacological and Genetic Disruption of C-Type Natriuretic Peptide (nppcl) Expression in Zebrafish (Danio rerio) Causes Stunted Growth during Development.

Genetic characterisation of the Connemara pony and the Warmblood horse using a within-breed clustering approach (2023)
Journal Article
Lindsay-McGee, V., Sanchez-Molano, E., Banos, G., Clark, E., Piercy, R., & Psifidi, A. (2023). Genetic characterisation of the Connemara pony and the Warmblood horse using a within-breed clustering approach. Genetics Selection Evolution, 55(1), https://doi.org/10.1186/s12711-023-00827-w

BackgroundThe Connemara pony (CP) is an Irish breed that has experienced varied selection by breeders over the last fifty years, with objectives ranging from the traditional hardy pony to an agile athlete. We compared these ponies with well-studied W... Read More about Genetic characterisation of the Connemara pony and the Warmblood horse using a within-breed clustering approach.

The tyrosine kinase inhibitor Dasatinib reduces cardiac steatosis and fibrosis in obese, type 2 diabetic mice (2023)
Journal Article
Gu, Y., Avolio, E., Alvino, V. V., Thomas, A. C., Herman, A., Miller, P. J., …Madeddu, P. (in press). The tyrosine kinase inhibitor Dasatinib reduces cardiac steatosis and fibrosis in obese, type 2 diabetic mice. Cardiovascular Diabetology, 22(1), https://doi.org/10.1186/s12933-023-01955-9

Genetic diversity, recombination and cross-species transmission of a waterbird gammacoronavirus in the wild (2023)
Journal Article
François, S., Nazki, S., Vickers, S. H., Fournié, G., Perrins, C. M., Broadbent, A. J., …Hill, S. C. (2023). Genetic diversity, recombination and cross-species transmission of a waterbird gammacoronavirus in the wild. Journal of General Virology, https://doi.org/10.1099/jgv.0.001883

Laparoscopic vs. open adrenalectomy: perioperative data and survival analysis in 70 dogs with an adrenal tumor (2023)
Journal Article
van Bokhorst, K. L., Galac, S., Kooistra, H. S., de Grauw, J. C., Teske, E., Grinwis, G. C. M., & van Nimwegen, S. A. (in press). Laparoscopic vs. open adrenalectomy: perioperative data and survival analysis in 70 dogs with an adrenal tumor. Frontiers in Veterinary Science, 10, https://doi.org/10.3389/fvets.2023.1156801

Endothelial AHR activity prevents lung barrier disruption in viral infection (2023)
Journal Article
Major, J., Crotta, S., Finsterbusch, K., Chakravarty, P., Shah, K., Frederico, B., …Wack, A. (2023). Endothelial AHR activity prevents lung barrier disruption in viral infection. Nature, https://doi.org/10.1038/s41586-023-06287-y

Disruption of the lung endothelial-epithelial cell barrier following respiratory virus infection causes cell and fluid accumulation in the air spaces and compromises vital gas exchange function(1). Endothelial dysfunction can exacerbate tissue damage... Read More about Endothelial AHR activity prevents lung barrier disruption in viral infection.

Macroevolutionary patterns in the pelvis, stylopodium and zeugopodium of megalosauroid theropod dinosaurs and their importance for locomotor function (2023)
Journal Article
Lacerda, M., Bittencourt, J., & Hutchinson, J. (2023). Macroevolutionary patterns in the pelvis, stylopodium and zeugopodium of megalosauroid theropod dinosaurs and their importance for locomotor function. Royal Society Open Science, 10(8), https://doi.org/10.1098/rsos.230481

During the Mesozoic, non-avian theropods represented one of the most successful clades globally distributed, with a wide diversity of forms. An example is the clade Megalosauroidea, which included medium- to large-bodied forms. Here, we analyse the m... Read More about Macroevolutionary patterns in the pelvis, stylopodium and zeugopodium of megalosauroid theropod dinosaurs and their importance for locomotor function.

Effect of Lavage Solution Type on Bronchoalveolar Lavage Fluid Cytology in Clinically Healthy Horses (2023)
Journal Article
Westermann, C. M., de Bie, A. G., Olave, C., de Grauw, J. C., Teske, E., & Couetil, L. L. (in press). Effect of Lavage Solution Type on Bronchoalveolar Lavage Fluid Cytology in Clinically Healthy Horses. Animals, 13(16), 2637. https://doi.org/10.3390/ani13162637

Equine induced pluripotent stem cells are responsive to inflammatory cytokines before and after differentiation into musculoskeletal cell types (2023)
Journal Article
Palomino Lago, E., Jelbert, E. R., Baird, A., Lam, P. Y., & Guest, D. J. (in press). Equine induced pluripotent stem cells are responsive to inflammatory cytokines before and after differentiation into musculoskeletal cell types. In Vitro Cellular and Developmental Biology - Animal, https://doi.org/10.1007/s11626-023-00800-3

DNA methylation networks underlying mammalian traits (2023)
Journal Article
Haghani, A., Li, C. Z., Robeck, T. R., Zhang, J., Lu, A. T., Ablaeva, J., …Horvath, S. (2023). DNA methylation networks underlying mammalian traits. Science, 381(6658), https://doi.org/10.1126/science.abq5693

Phylodynamic approaches to studying avian influenza virus: a review (2023)
Journal Article
Carnegie, L., Raghwani, J., Fournié, G., & Hill, S. (2023). Phylodynamic approaches to studying avian influenza virus: a review. Avian Pathology, https://doi.org/10.1080/03079457.2023.2236568

A machine learning-based image segmentation method to quantify in vitro osteoclast culture endpoints (2023)
Journal Article
Davies, B., Hibbert, A., Roberts, S., Roberts, H., Tickner, J., Holdsworth, G., …Orriss, I. (in press). A machine learning-based image segmentation method to quantify in vitro osteoclast culture endpoints. Calcified Tissue International, https://doi.org/10.1007/s00223-023-01121-z

Universal DNA methylation age across mammalian tissues (2023)
Journal Article
Lu, A. T., Fei, Z., Haghani, A., Robeck, T. R., Zoller, J. A., Li, C. Z., …Horvath, S. (in press). Universal DNA methylation age across mammalian tissues. Nature Aging, 3(9), 1144-1166. https://doi.org/10.1038/s43587-023-00462-6

Dropped-head syndrome in a dog secondary to myopathy of the cervical extensor muscles (2023)
Journal Article
Grapes, N., Llabres-Diaz, F., Vicent, N., De Stefani, A., & De Decker, S. (2023). Dropped-head syndrome in a dog secondary to myopathy of the cervical extensor muscles. Vet Record Case Reports, https://doi.org/10.1002/vrc2.654

A 4-year-old, male, entire Newfoundland was presented for investigation of an acute onset cervical ventroflexion and pyrexia, 4 days following a hip replacement surgery. Neurological examination confirmed prominent cervical ventroflexion characterise... Read More about Dropped-head syndrome in a dog secondary to myopathy of the cervical extensor muscles.

Diagnostic quality of ultrasound-guided fine-needle aspirates samples from the canine liver and spleen is not significantly affected by using 22-, 23-, and 25-gauge needles (2023)
Journal Article
Llanos, C., Holmes, E., White, C., Jasensky, A., & Fitzgerald, E. (2023). Diagnostic quality of ultrasound-guided fine-needle aspirates samples from the canine liver and spleen is not significantly affected by using 22-, 23-, and 25-gauge needles. Veterinary Radiology and Ultrasound, https://doi.org/10.1111/vru.13290

Ultrasound-guided fine-needle aspirates (FNA) of the liver and spleen for cytological analysis are a commonly performed procedure in canine veterinary practice. Based on our review of the literature, this is the first published study investigating wh... Read More about Diagnostic quality of ultrasound-guided fine-needle aspirates samples from the canine liver and spleen is not significantly affected by using 22-, 23-, and 25-gauge needles.

Targeted dosing for susceptible heteroresistant subpopulations may improve rational dosage regimen prediction for colistin in broiler chickens (2023)
Journal Article
Mead, A., Toutain, P., Richez, P., & Pelligand, L. (2023). Targeted dosing for susceptible heteroresistant subpopulations may improve rational dosage regimen prediction for colistin in broiler chickens. Scientific Reports, 13, Article 12822. https://doi.org/10.1038/s41598-023-39727-w

The dosage of colistin for the treatment of enteric E. coli in animals necessitates considering the heteroresistant (HR) nature of the targeted inoculum, described by the presence of a major susceptible population (S1, representing 99.95% of total po... Read More about Targeted dosing for susceptible heteroresistant subpopulations may improve rational dosage regimen prediction for colistin in broiler chickens.

Evidence that pyrophosphate acts as an extracellular signalling molecule to exert direct functional effects on primary osteoblasts and osteoclasts (2023)
Journal Article
Orriss, I., Wheeler-Jones, C., Roberts, S., & Keen, J. (in press). Evidence that pyrophosphate acts as an extracellular signalling molecule to exert direct functional effects on primary osteoblasts and osteoclasts. BONE, https://doi.org/10.1016/j.bone.2023.116868

Development of a body condition index to estimate adiposity in ponies and horses from morphometric measurements (2023)
Journal Article
Menzies-Gow, N., & Knowles, E. (2023). Development of a body condition index to estimate adiposity in ponies and horses from morphometric measurements. Equine Veterinary Journal, https://doi.org/10.1111/evj.13975

Gestation Length is Associated With Early-Life Limb Deformities in Thoroughbred Foals (2023)
Journal Article
Mouncey, R., Arango-Sabogal, J., de Mestre, A., & Verheyen, K. (2023). Gestation Length is Associated With Early-Life Limb Deformities in Thoroughbred Foals. Journal of Equine Veterinary Science, 129, https://doi.org/10.1016/j.jevs.2023.104896

Flexural and angular limb deformities (LD) are an important cause of early-life morbidity and mortality/euthanasia in Thoroughbred foals. The majority are congenital in origin but, to date, their precise aetiology is poorly understood. We hypothesize... Read More about Gestation Length is Associated With Early-Life Limb Deformities in Thoroughbred Foals.

Analysis of lower urinary tract signs and bacteriuria in cats with subcutaneous ureteral bypass systems (2023)
Journal Article
Djoneva, L., Lawson, J., Rutherford, L., & Geddes, R. (2023). Analysis of lower urinary tract signs and bacteriuria in cats with subcutaneous ureteral bypass systems. Vet Record Open, 10(2), https://doi.org/10.1002/vro2.69

ObjectivesDistinguishing bacterial cystitis from subclinical bacteriuria is necessary for feline treatment protocols and antimicrobial stewardship. This can be challenging in cats with subcutaneous ureteral bypass (SUB) systems because they may prese... Read More about Analysis of lower urinary tract signs and bacteriuria in cats with subcutaneous ureteral bypass systems.