Quantification of global transcription patterns in prokaryotes using spotted microarrays
(2007)
Journal Article
Sidders, B., Withers, M., Kendall, S. L., Bacon, J., Waddell, S. J., Hinds, J., Golby, P., Movahedzadeh, F., Cox, R. A., Frita, R., Ten Bokum, A. M. C., Wernisch, L., & Stoker, N. G. (2007). Quantification of global transcription patterns in prokaryotes using spotted microarrays. Genome Biology, 8(12), R265. https://doi.org/10.1186/gb-2007-8-12-r265
We describe an analysis, applicable to any spotted microarray dataset produced using genomic DNA as a reference, that quantifies prokaryotic levels of mRNA on a genome-wide scale. Applying this to Mycobacterium tuberculosis, we validate the technique... Read More about Quantification of global transcription patterns in prokaryotes using spotted microarrays.