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Enhanced flight performance by genetic manipulation of wing shape in Drosophila (2016)
Journal Article
Ray, R. P., Nakata, T., Henningsson, P., & Bomphrey, R. J. (2016). Enhanced flight performance by genetic manipulation of wing shape in Drosophila. Nature Communications, 7, https://doi.org/10.1038/ncomms10851

Insect wing shapes are remarkably diverse and the combination of shape and kinematics determines both aerial capabilities and power requirements. However, the contribution of any specific morphological feature to performance is not known. Using targe... Read More about Enhanced flight performance by genetic manipulation of wing shape in Drosophila.

Asymptomatic and Submicroscopic Carriage of Plasmodium knowlesi Malaria in Household and Community Members of Clinical Cases in Sabah, Malaysia (2016)
Journal Article
Fornace, K. M., Nuin, N. A., Betson, M., Grigg, M. J., William, T., Anstey, N. M., …Drakeley, C. J. (2016). Asymptomatic and Submicroscopic Carriage of Plasmodium knowlesi Malaria in Household and Community Members of Clinical Cases in Sabah, Malaysia. Journal of Infectious Diseases, 213(5), 784-787. https://doi.org/10.1093/infdis/jiv475

Chronic kidney disease in aged cats: Clinical features, morphology, and proposed pathogeneses (2016)
Journal Article
Brown, C., Elliott, J., Schmiedt, C., & Brown, S. (2016). Chronic kidney disease in aged cats: Clinical features, morphology, and proposed pathogeneses. Veterinary Pathology, 53(2), 309-326. https://doi.org/10.1177/0300985815622975

Chronic kidney disease (CKD) is the most common metabolic disease of domesticated cats, with most affected cats being geriatric (>12 years of age). The prevalence of CKD in cats exceeds that observed in dogs, and the frequency of the diagnosis of CKD... Read More about Chronic kidney disease in aged cats: Clinical features, morphology, and proposed pathogeneses.

Addition of magnesium sulphate to ropivacaine for spinal analgesia in dogs undergoing tibial plateau levelling osteotomy (2016)
Journal Article
Adami, C., Casoni, D., Noussitou, F., Rytz, U., & Spadavecchia, C. (2016). Addition of magnesium sulphate to ropivacaine for spinal analgesia in dogs undergoing tibial plateau levelling osteotomy. https://doi.org/10.1016/j.tvjl.2015.11.017

The aim of this blinded, randomised, prospective clinical trial was to determine whether the addition of magnesium sulphate to spinally-administered ropivacaine would improve peri-operative analgesia without impairing motor function in dogs undergoin... Read More about Addition of magnesium sulphate to ropivacaine for spinal analgesia in dogs undergoing tibial plateau levelling osteotomy.

Serum Biochemical Phenotypes in the Domestic Dog (2016)
Journal Article
Chang, Y. M., Hadox, E., Szladovits, B., & Garden, O. A. (2016). Serum Biochemical Phenotypes in the Domestic Dog. PLoS ONE, 11(2), e0149650. https://doi.org/10.1371/journal.pone.0149650

The serum or plasma biochemical profile is essential in the diagnosis and monitoring of systemic disease in veterinary medicine, but current reference intervals typically take no account of breed-specific differences. Breed-specific hematological phe... Read More about Serum Biochemical Phenotypes in the Domestic Dog.

Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease (2016)
Journal Article
Deas, E., Cremades, N., Angelova, P. R., Ludtmann, M. H. R., Yao, Z., Chen, S., …Abramov, A. Y. (2016). Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease. https://doi.org/10.1089/ars.2015.6343

Protein aggregation and oxidative stress are both key pathogenic processes in Parkinson's disease, although the mechanism by which misfolded proteins induce oxidative stress and neuronal death remains unknown. In this study, we describe how aggregati... Read More about Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease.

Prenatal muscle development in a mouse model for the secondary dystroglycanopathies (2016)
Journal Article
Kim, J., Hopkinson, M., Kavishwar, M., Fernandez-Fuente, M., & Brown, S. C. (2016). Prenatal muscle development in a mouse model for the secondary dystroglycanopathies. Skeletal Muscle, 6(3), https://doi.org/10.1186/s13395-016-0073-y

The defective glycosylation of α-dystroglycan is associated with a group of muscular dystrophies that are collectively referred to as the secondary dystroglycanopathies. Mutations in the gene encoding fukutin-related protein (FKRP) are one of the mos... Read More about Prenatal muscle development in a mouse model for the secondary dystroglycanopathies.