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Histopathologic Concordance Of Concurrent Duodenal And Ileal Biopsy Specimens In Dogs With Inflammatory Or Neoplastic Disease Blinded (2021)
Journal Article
Kathrani, A., Priestnall, S., & Caulfield, S. (2021). Histopathologic Concordance Of Concurrent Duodenal And Ileal Biopsy Specimens In Dogs With Inflammatory Or Neoplastic Disease Blinded. Journal of Veterinary Internal Medicine, https://doi.org/10.3390/ani11102938

Background
Histopathologic discordance between intestinal locations in canine chronic enteropathy has prompted recommendations to biopsy both duodenal and ileal sites to minimize lesion oversight. Further evaluation is required for dogs with non-chr... Read More about Histopathologic Concordance Of Concurrent Duodenal And Ileal Biopsy Specimens In Dogs With Inflammatory Or Neoplastic Disease Blinded.

Dissecting the Phenotype and Genotype of PLA2G6‐Related Parkinsonism (2021)
Journal Article
Magrinelli, F., Mehta, S., Di Lazzaro, G., Latorre, A., Edwards, M. J., Balint, B., Basu, P., Kobylecki, C., Groppa, S., Hegde, A., Mulroy, E., Estevez‐Fraga, C., Arora, A., Kumar, H., Schneider, S. A., Lewis, P. A., Jaunmuktane, Z., Revesz, T., Gandhi, S., Wood, N. W., …Bhatia, K. P. (in press). Dissecting the Phenotype and Genotype of PLA2G6‐Related Parkinsonism. Movement Disorders, https://doi.org/10.1002/mds.28807

Background

Complex parkinsonism is the commonest phenotype in late-onset PLA2G6-associated neurodegeneration.

Objectives

The aim of this study was to deeply characterize phenogenotypically PLA2G6-related parkinsonism in the largest cohort ev... Read More about Dissecting the Phenotype and Genotype of PLA2G6‐Related Parkinsonism.

Determination of colistin in luminal and parietal intestinal matrices of chicken by ultra-high performance liquid chromatography-tandem mass spectrometry (2021)
Journal Article
Mead, A., Gillard, N., Robert, C., Richez, P., Pierret, G., Henrottin, J., & Pelligand, L. (2021). Determination of colistin in luminal and parietal intestinal matrices of chicken by ultra-high performance liquid chromatography-tandem mass spectrometry. Journal of Veterinary Pharmacology and Therapeutics, https://doi.org/10.1111/jvp.13022

Justification for continued use of colistin in veterinary medicine, e.g. medicated water, relies on pharmacokinetic/pharmacodynamic (PK/PD) studies that require accurate measurement of colistin content in the digestive tract. A method for the detect... Read More about Determination of colistin in luminal and parietal intestinal matrices of chicken by ultra-high performance liquid chromatography-tandem mass spectrometry.

Comparison of the transcriptome in circulating leukocytes in early lactation between primiparous and multiparous cows provides evidence for age-related changes (2021)
Journal Article
Buggiotti, L., Cheng, Z., Salavati, M., Wathes, C., & GplusE Consortium. (2021). Comparison of the transcriptome in circulating leukocytes in early lactation between primiparous and multiparous cows provides evidence for age-related changes. BMC Genomics, https://doi.org/10.1186/s12864-021-07977-5

Background: Previous studies have identified many immune pathways which are consistently altered in humans and model organisms as they age. Dairy cows are often culled at quite young ages due to an inability to cope adequately with metabolic and infe... Read More about Comparison of the transcriptome in circulating leukocytes in early lactation between primiparous and multiparous cows provides evidence for age-related changes.

Controlling the causative agents of coccidiosis in domestic chickens; an eye on the 1 past and considerations for the future 2 (2021)
Journal Article
Attree, E., Sanchez-Arsuaga, G., Jones, M., Xia, D., -Hernandez, M., Blake, D., & Tomley, F. (2021). Controlling the causative agents of coccidiosis in domestic chickens; an eye on the 1 past and considerations for the future 2. CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources, https://doi.org/10.1186/s43170-021-00056-5

Coccidiosis is a potentially severe enteritis caused by species of obligate intracellular parasites of the genus Eimeria. These parasites cause significant economic losses to the poultry industry, predominantly due to compromised efficiency of produc... Read More about Controlling the causative agents of coccidiosis in domestic chickens; an eye on the 1 past and considerations for the future 2.

Effect of topical antimicrobial therapy and household cleaning on meticillin-resistant Staphylococcus pseudintermedius carriage in dogs (2021)
Journal Article
Frosini, S. M., Bond, R., King, R., Feudi, C., Schwarz, S., & Loeffler, A. (2021). Effect of topical antimicrobial therapy and household cleaning on meticillin-resistant Staphylococcus pseudintermedius carriage in dogs. BMJ Open, https://doi.org/10.1002/vetr.937

Abstract
MRSP is a multidrug-resistant, zoonotic canine pathogen. This study investigated MRSP carriage and clearance through topical antimicrobial therapy and household cleaning in dogs recovered from MRSP infection.
Dogs were swabbed for MRSP c... Read More about Effect of topical antimicrobial therapy and household cleaning on meticillin-resistant Staphylococcus pseudintermedius carriage in dogs.

Human pluripotent stem cell-derived cartilaginous organoids promote scaffold-free healing of critical size long bone defects (2021)
Journal Article
Tam, W. L., Freitas Mendes, L., Chen, X., Lesage, R., Van Hoven, I., Leysen, E., Kerckhofs, G., Bosmans, K., Chai, Y. C., Yamashita, A., Tsumaki, N., Geris, L., Roberts, S. J., & Luyten, F. P. (2021). Human pluripotent stem cell-derived cartilaginous organoids promote scaffold-free healing of critical size long bone defects. Stem Cell Research and Therapy, 12(1), https://doi.org/10.1186/s13287-021-02580-7

Background
Bones have a remarkable capacity to heal upon fracture. Yet, in large defects or compromised conditions healing processes become impaired, resulting in delayed or non-union. Current therapeutic approaches often utilize autologous or allog... Read More about Human pluripotent stem cell-derived cartilaginous organoids promote scaffold-free healing of critical size long bone defects.

Financial impact of sheeppox and goatpox and estimated profitability of vaccination for subsistence farmers in selected northern states of Nigeria (2021)
Journal Article
Rawlins, M., Limon, G., Adedeji, A., Ijoma, S., Atai, R., Adole, J., Dogonyaro, B., Joel, A., Beard, P., & Alarcon, P. (2022). Financial impact of sheeppox and goatpox and estimated profitability of vaccination for subsistence farmers in selected northern states of Nigeria. Preventative Veterinary Medicine, 198, https://doi.org/10.1016/j.prevetmed.2021.105503

Sheeppox and goatpox (SGP) are important transboundary diseases, endemic in Nigeria, causing severe clinical manifestations, impacting production, and resulting in economic losses. Vaccination is an effective control measure against SGP in endemic co... Read More about Financial impact of sheeppox and goatpox and estimated profitability of vaccination for subsistence farmers in selected northern states of Nigeria.

Challenges and solutions for diabetes early career researchers in the COVID-19 recovery – perspectives of the Diabetes UK Innovators in Diabetes (2021)
Journal Article
Gage, M. (in press). Challenges and solutions for diabetes early career researchers in the COVID-19 recovery – perspectives of the Diabetes UK Innovators in Diabetes. Diabetic Medicine, https://doi.org/10.1111/dme.14698

The COVID-19 pandemic has put diabetes at the forefront of conversation. The prevalence of type 2 diabetes in the UK is high1 and has links to adverse COVID-19 outcomes2. Research investigating the links between these two public health issues are mov... Read More about Challenges and solutions for diabetes early career researchers in the COVID-19 recovery – perspectives of the Diabetes UK Innovators in Diabetes.

The critical dynamic role of the tail in bipedal dinosaur locomotion (2021)
Journal Article
Bishop, P., Falisse, A., De Groote, F., & Hutchinson, J. (2021). The critical dynamic role of the tail in bipedal dinosaur locomotion. Science Advances, https://doi.org/10.1126/sciadv.abi7348

Locomotion has influenced the ecology, evolution, and extinction of species throughout history, yet studying locomotion in the fossil record is challenging. Computational biomechanics can provide novel insight by mechanistically relating observed ana... Read More about The critical dynamic role of the tail in bipedal dinosaur locomotion.

Cross-sectional study of approaches to diagnosis and management of dogs with immune-mediated haemolytic anaemia in primary care and referral veterinary practices in the United Kingdom (2021)
Journal Article
Glanemann, B., Tayler, S., Sparrow, R., Skelly, B., Swann, J., & Hall, H. (2021). Cross-sectional study of approaches to diagnosis and management of dogs with immune-mediated haemolytic anaemia in primary care and referral veterinary practices in the United Kingdom. PLoS ONE, https://doi.org/10.1371/journal.pone.0257700

Objectives: To determine whether veterinarians in PCPs and BCCs approach treatment of dogs with IMHA similarly, and whether practitioners with more experience treat similarly to those with less experience. We hypothesised those in PCPs would show mo... Read More about Cross-sectional study of approaches to diagnosis and management of dogs with immune-mediated haemolytic anaemia in primary care and referral veterinary practices in the United Kingdom.

S1P in the development of atherosclerosis: roles of haemodynamic wall shear stress and endothelial permeability (2021)
Journal Article
Warboys, C. M., & Weinberg, P. D. (2021). S1P in the development of atherosclerosis: roles of haemodynamic wall shear stress and endothelial permeability. Tissue Barriers, https://doi.org/10.1080/21688370.2021.1959243

Atherosclerosis is characterised by focal accumulations of lipid within the arterial wall, thought to arise from effects of haemodynamic wall shear stress (WSS) on endothelial permeability. Identifying pathways that mediate effects of shear on permea... Read More about S1P in the development of atherosclerosis: roles of haemodynamic wall shear stress and endothelial permeability.

Epidemiology of bovine brucellosis in Hisar, India: identification of risk factors and assessment of knowledge, attitudes, and practices among livestock owners (2021)
Journal Article
Saidu, A. S., Mahajan, N. K., Musallam, I. I., Holt, H. R., & Guitian, J. (2021). Epidemiology of bovine brucellosis in Hisar, India: identification of risk factors and assessment of knowledge, attitudes, and practices among livestock owners. Tropical Animal Health and Production, 53(5), https://doi.org/10.1007/s11250-021-02884-z