Skip to main content

Research Repository

Advanced Search

All Outputs (10086)

Mitochondria form cholesterol-rich contact sites with the nucleus during retrograde response (2020)
Journal Article
Desai, R., East, D. A., Hardy, L., Crosby, J., Faccenda, D., Alvarex, M. S., …Campanella, M. (2020). Mitochondria form cholesterol-rich contact sites with the nucleus during retrograde response. Science Advances, https://doi.org/10.1101/445411

Cholesterol metabolism is pivotal to cellular homeostasis, hormones production, and membranes composition. Its dysregulation associates with malignant reprogramming and therapy resistance. Cholesterol is trafficked into the mitochondria for steroidog... Read More about Mitochondria form cholesterol-rich contact sites with the nucleus during retrograde response.

Evaluation of Pneumococcal Serotyping of Nasopharyngeal-Carriage Isolates by Latex Agglutination, Whole-Genome Sequencing (PneumoCaT), and DNA Microarray in a High-Pneumococcal-Carriage-Prevalence Population in Malawi (2020)
Journal Article
Swarthout, T., Gori, A., Bar-Zeev, N., Kamng'ona, A., Mwalukomo, T., Bonomali, F., …French, N. (2021). Evaluation of Pneumococcal Serotyping of Nasopharyngeal-Carriage Isolates by Latex Agglutination, Whole-Genome Sequencing (PneumoCaT), and DNA Microarray in a High-Pneumococcal-Carriage-Prevalence Population in Malawi. Journal of Clinical Microbiology, 59(1), https://doi.org/10.1128/JCM.02103-20

Accurate assessment of the serotype distribution associated with pneumococcal colonization and disease is essential for evaluating and formulating pneumococcal vaccines and for informing vaccine policy. For this reason, we evaluated the concordance b... Read More about Evaluation of Pneumococcal Serotyping of Nasopharyngeal-Carriage Isolates by Latex Agglutination, Whole-Genome Sequencing (PneumoCaT), and DNA Microarray in a High-Pneumococcal-Carriage-Prevalence Population in Malawi.

Mining the Unmapped Reads in Bovine RNA-Seq Data Reveals the Prevalence of Bovine Herpes Virus-6 in European Dairy Cows and the Associated Changes in Their Phenotype and Leucocyte Transcriptome (2020)
Journal Article
Buggiotti, L., Cheng, Z., Wathes, C., & GplusE Consortium, G. (in press). Mining the Unmapped Reads in Bovine RNA-Seq Data Reveals the Prevalence of Bovine Herpes Virus-6 in European Dairy Cows and the Associated Changes in Their Phenotype and Leucocyte Transcriptome. Viruses, 12(12), 1451. https://doi.org/10.3390/v12121451

Microbial RNA is detectable in host samples by aligning unmapped reads from RNA sequencing against taxon reference sequences, generating a score proportional to the microbial load. An RNA-Seq data analysis showed that 83.5% of leukocyte samples from... Read More about Mining the Unmapped Reads in Bovine RNA-Seq Data Reveals the Prevalence of Bovine Herpes Virus-6 in European Dairy Cows and the Associated Changes in Their Phenotype and Leucocyte Transcriptome.

Incidence and risk factors for feline lymphoma in UK primary-care practice (2020)
Journal Article
Economu, L. (in press). Incidence and risk factors for feline lymphoma in UK primary-care practice. Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13266

Objectives: The study aimed to estimate the incidence and prevalence of feline lymphoma in cats attending primary-care practices across the UK and to identify patient-based and environmental (radon and pesticide exposure) risk factors. Materials a... Read More about Incidence and risk factors for feline lymphoma in UK primary-care practice.

The Application of Bacteriophage Diagnostics for Bacterial Pathogens in the Agricultural Supply Chain: From Farm-to-Fork (2020)
Journal Article
Jones, H. J., Shield, C. G., & Swift, B. M. (2020). The Application of Bacteriophage Diagnostics for Bacterial Pathogens in the Agricultural Supply Chain: From Farm-to-Fork. PHAGE Therapy, Applications, and Research, 1(4), 176-188. https://doi.org/10.1089/phage.2020.0042

Bacteriophages (phages) have great potential not only as therapeutics but as diagnostics. Indeed, they have been developed and used to diagnose and detect bacterial infections, primarily in human clinical settings. The ability to rapidly detect and c... Read More about The Application of Bacteriophage Diagnostics for Bacterial Pathogens in the Agricultural Supply Chain: From Farm-to-Fork.

Association of immune responses of Zebu and Holstein‐Friesian cattle and resistance to mycobacteria in a BCG challenge model (2020)
Journal Article
Alcaraz‐López, O. A., Flores‐Villalva, S., Cortéz‐Hernández, O., Vigueras‐Meneses, G., Carrisoza‐Urbina, J., Benítez‐Guzmán, A., …Gutiérrez‐Pabello, J. A. (in press). Association of immune responses of Zebu and Holstein‐Friesian cattle and resistance to mycobacteria in a BCG challenge model. Transboundary and Emerging Diseases, https://doi.org/10.1111/tbed.13939

Seroprevalence and associated risk factors of Dengue fever in Kassala state, eastern Sudan (2020)
Journal Article
Elaagip, A., Alsedig, K., Altahir, O., Ageep, T., Ahmed, A., Siam, H. A., …Abdel Hamid, M. M. (in press). Seroprevalence and associated risk factors of Dengue fever in Kassala state, eastern Sudan. PLoS Neglected Tropical Diseases, 14(12), e0008918. https://doi.org/10.1371/journal.pntd.0008918

Dengue is a rapidly growing public health threat in Kassala state, eastern Sudan. The objective of this study was to determine the seroprevalence, entomological transmission indices, and socioeconomic risk factors associated with dengue in this regio... Read More about Seroprevalence and associated risk factors of Dengue fever in Kassala state, eastern Sudan.

Limb work and joint work minimization reveal an energetic benefit to the elbows-back, knees-forward limb design in parasagittal quadrupeds (2020)
Journal Article
Usherwood, J. R., & Granatosky, M. C. (2020). Limb work and joint work minimization reveal an energetic benefit to the elbows-back, knees-forward limb design in parasagittal quadrupeds. Proceedings of the Royal Society B: Biological Sciences, 287(1940), 20201517. https://doi.org/10.1098/rspb.2020.1517

Quadrupedal animal locomotion is energetically costly. We explore two forms of mechanical work that may be relevant in imposing these physiological demands. Limb work, due to the forces and velocities between the stance foot and the centre of mass, c... Read More about Limb work and joint work minimization reveal an energetic benefit to the elbows-back, knees-forward limb design in parasagittal quadrupeds.

Breed predispositions, clinical findings, and prognostic factors for death in dogs with nonregenerative immune‐mediated anemia (2020)
Journal Article
Szladovits, B., & Glanemann, B. (in press). Breed predispositions, clinical findings, and prognostic factors for death in dogs with nonregenerative immune‐mediated anemia. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.15986

Abstract Background: Breed predispositions, survival, and prognostic factors have not been evaluated in dogs with nonregenerative immune-mediated anemia (nrIMA). Hypothesis/Objectives: To describe clinicopathologic variables, evaluate their associa... Read More about Breed predispositions, clinical findings, and prognostic factors for death in dogs with nonregenerative immune‐mediated anemia.

Epidemiology of COVID-19 infection in young children under five years: A systematic review and meta-analysis (2020)
Journal Article
Bhuiyan, M. U., Stiboy, E., Hassan, M. Z., Chan, M., Islam, M. S., Haider, N., …Homaira, N. (2020). Epidemiology of COVID-19 infection in young children under five years: A systematic review and meta-analysis. Vaccine, https://doi.org/10.1016/j.vaccine.2020.11.078

Introduction Emerging evidence suggests young children are at greater risk of COVID-19 infection than initially predicted. However, a comprehensive understanding of epidemiology of COVID-19 infection in young children under five years, the most at-r... Read More about Epidemiology of COVID-19 infection in young children under five years: A systematic review and meta-analysis.

Prospective evaluation of pericardial catheter placement versus needle pericardiocentesis in the management of canine pericardial effusion (2020)
Journal Article
Cook, S. (2020). Prospective evaluation of pericardial catheter placement versus needle pericardiocentesis in the management of canine pericardial effusion. Journal of Veterinary Emergency and Critical Care, https://doi.org/10.1111/vec.13030

Objective To compare the safety and efficacy of pericardial catheter placement with needle pericardiocentesis in dogs with pericardial effusion (PE) Design Prospective, pilot randomized trial. Setting University teaching hospital. Animals Thir... Read More about Prospective evaluation of pericardial catheter placement versus needle pericardiocentesis in the management of canine pericardial effusion.

Medium-chain triglycerides dietary supplement improves cognitive abilities in canine epilepsy (2020)
Journal Article
Andreas Berk, B., Packer, R. M. A., Hong Law, T., Wessmann, A., Bathen-Nöthen, A., Jokinen, T. S., …Volk, H. A. (in press). Medium-chain triglycerides dietary supplement improves cognitive abilities in canine epilepsy. Epilepsy & Behavior, https://doi.org/10.1016/j.yebeh.2020.107608

Objective: Cognitive impairments (CI) have recently been identified in canine epilepsy patients. A medium-chain triglyceride (MCT) enriched diet has been demonstrated to improve cognition in aged dogs and seizure control in canine epilepsy. This stud... Read More about Medium-chain triglycerides dietary supplement improves cognitive abilities in canine epilepsy.

Student Involvement in Global Veterinary Education and Curricula: 7 Years of Progress (2013–2019) (2020)
Journal Article
Liatis, T., Patel, B., Huang, M., Buren, L., & Kotsadam, G. (2020). Student Involvement in Global Veterinary Education and Curricula: 7 Years of Progress (2013–2019). Journal of Veterinary Medical Education, 47(4), 379-383. https://doi.org/10.3138/jvme.2018-0021

As central members of the veterinary education community, students are well placed to highlight current problems in veterinary education. Motivated by the lack of current formal student involvement, the largest global veterinary student association,... Read More about Student Involvement in Global Veterinary Education and Curricula: 7 Years of Progress (2013–2019).

Investigation of the transforming growth factor-beta 1 signalling pathway as a possible link between hyperphosphataemia and renal fibrosis in feline chronic kidney disease (2020)
Journal Article
Lawson, J., Syme, H., Wheeler-Jones, C., & Elliott, J. (2020). Investigation of the transforming growth factor-beta 1 signalling pathway as a possible link between hyperphosphataemia and renal fibrosis in feline chronic kidney disease. The Veterinary Journal, 267, 105582. https://doi.org/10.1016/j.tvjl.2020.105582

Chronic kidney disease (CKD) is common in geriatric cats, and is characterised in the majority of cases by tubulointerstitial inflammation and fibrosis. Hyperphosphataemia is a frequent complication of CKD and is independently associated with severit... Read More about Investigation of the transforming growth factor-beta 1 signalling pathway as a possible link between hyperphosphataemia and renal fibrosis in feline chronic kidney disease.

Early CT in dogs following traumatic brain injury has limited value in predicting short‐term prognosis (2020)
Journal Article
Lee, C. Y., Llabres‐Diaz, F., Wyatt, S., & Beltran, E. (2021). Early CT in dogs following traumatic brain injury has limited value in predicting short‐term prognosis. Veterinary Radiology and Ultrasound, 62(2), 181-189. https://doi.org/10.1111/vru.12933

Traumatic brain injury is associated with a high risk of mortality in veterinary patients, however publications describing valid prognostic indicators are currently lacking. The objective of this retrospective observational study was to determine whe... Read More about Early CT in dogs following traumatic brain injury has limited value in predicting short‐term prognosis.

COVID-19—Zoonosis or Emerging Infectious Disease? (2020)
Journal Article
Haider, N., Rothman-Ostrow, P., Osman, A. Y., Arruda, L. B., Macfarlane-Berry, L., Elton, L., …Kock, R. A. (in press). COVID-19—Zoonosis or Emerging Infectious Disease?. Frontiers in Public Health, 8, https://doi.org/10.3389/fpubh.2020.596944

The World Health Organization defines a zoonosis as any infection naturally transmissible from vertebrate animals to humans. The pandemic of Coronavirus disease (COVID-19) caused by SARS-CoV-2 has been classified as a zoonotic disease, however, no an... Read More about COVID-19—Zoonosis or Emerging Infectious Disease?.