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Clinical, pathological and functional characterization of riboflavin-responsive neuropathy (2017)
Journal Article
Manole, A., Jaunmuktane, Z., Hargreaves, I., Ludtmann, M. H. R., Pandraud, A., Salpietro, V., Pope, S., Horga, A., Scalco, R. S., Li, A., Ashokkumar, B., Lourenço, C. M., Horvath, R., Chinnery, P. F., Toro, C., Singleton, A. B., Abramov, A. Y., Muntoni, F., Hanna, F. G., Reilly, M. M., …Houlden, H. (2017). Clinical, pathological and functional characterization of riboflavin-responsive neuropathy. Brain, 140(11), 2820-2837. https://doi.org/10.1093/brain/awx231

Brown-Vialetto-Van Laere syndrome represents a phenotypic spectrum of motor, sensory, and cranial nerve neuropathy, often with ataxia, optic atrophy and respiratory problems leading to ventilator-dependence. Loss-of-function mutations in two riboflav... Read More about Clinical, pathological and functional characterization of riboflavin-responsive neuropathy.

Practices of traditional beef farmers in their production and marketing of cattle in Zambia (2017)
Journal Article
Mumba, C., Haesler, B., Muma, J. B., Munyeme, M., Sitali, D. C., Skjerve, E., & Rich, K. M. (2017). Practices of traditional beef farmers in their production and marketing of cattle in Zambia. Tropical Animal Health and Production, 50(1), 49-62. https://doi.org/10.1007/s11250-017-1399-0

Understanding the practices of traditional cattle farmers in developing countries is an important factor in the development of appropriate, pro-poor disease control policies, and in formulating regional-specific production incentives that can improve... Read More about Practices of traditional beef farmers in their production and marketing of cattle in Zambia.

Effects of Eimeria tenella infection on chicken caecal microbiome diversity, exploring variation associated with severity of pathology (2017)
Journal Article
Macdonald, S. E., Nolan, M. J., Harman, K., Boulton, K., Hume, D. A., Tomley, F. M., Stabler, R. A., & Blake, D. P. (2017). Effects of Eimeria tenella infection on chicken caecal microbiome diversity, exploring variation associated with severity of pathology. PLoS ONE, 12(9), e0184890. https://doi.org/10.1371/journal.pone.0184890

Eimeria species cause the intestinal disease coccidiosis, most notably in poultry. While the direct impact of coccidiosis on animal health and welfare is clear, its influence on the enteric microbiota and by-stander effects on chicken health and prod... Read More about Effects of Eimeria tenella infection on chicken caecal microbiome diversity, exploring variation associated with severity of pathology.

A novel mammalian glucokinase exhibiting exclusive inorganic polyphosphate dependence in the cell nucleus (2017)
Journal Article
Ali, A., Wathes, D. C., Swali, A., Burns, H., & Burns, S. (2017). A novel mammalian glucokinase exhibiting exclusive inorganic polyphosphate dependence in the cell nucleus. https://doi.org/10.1016/j.bbrep.2017.09.004

We report the discovery of a polyphosphate-dependent enzyme system in mammalian cells with kinetics similar to established ATP-dependent glucokinase, also known to have a nuclear location. The kinetics suggest possible regulatory or redox protective... Read More about A novel mammalian glucokinase exhibiting exclusive inorganic polyphosphate dependence in the cell nucleus.

The cholesterol ester cycle regulates signalling complexes and synapse damage caused by amyloid-ß (2017)
Journal Article
West, E., Osborne, C., & Bate, C. (2017). The cholesterol ester cycle regulates signalling complexes and synapse damage caused by amyloid-ß. Journal of Cell Science, 130, 3050-3059. https://doi.org/10.1242/jcs.205484

Cholesterol is required for the formation and function of some signalling platforms. In synaptosomes, amyloid-β (Aβ) oligomers, the causative agent in Alzheimer's disease, bind to cellular prion proteins (PrPC) resulting in increased cholesterol conc... Read More about The cholesterol ester cycle regulates signalling complexes and synapse damage caused by amyloid-ß.

Economic evaluation of the eradication program for bovine viral diarrhea in the Swiss dairy sector (2017)
Journal Article
Thomann, B., Tschopp, A., Magouras, I., Meylan, M., Schüpbach-Regula, G., & Häsler, B. (2017). Economic evaluation of the eradication program for bovine viral diarrhea in the Swiss dairy sector. Preventive Veterinary Medicine, 145, 1-6. https://doi.org/10.1016/j.prevetmed.2017.05.020

The aim of this study was to conduct an economic evaluation of the BVD eradication program in the Swiss dairy sector. The situation before the start of the program (herd-level prevalence: 20%) served as a baseline scenario. Production models for thre... Read More about Economic evaluation of the eradication program for bovine viral diarrhea in the Swiss dairy sector.

Acceptance of home blood glucose monitoring by owners of recently diagnosed diabetic cats and impact on quality of life changes in cat and owner (2017)
Journal Article
Hazuchova, K., Gostelow, R., Scudder, C. J., Forcada, Y., Church, D. B., & Niessen, S. J. M. (2017). Acceptance of home blood glucose monitoring by owners of recently diagnosed diabetic cats and impact on quality of life changes in cat and owner. Journal of Feline Medicine and Surgery, 20(8), 711-720. https://doi.org/10.1177/1098612X17727692

Work minimization accounts for footfall phasing in slow quadrupedal gaits (2017)
Journal Article
Usherwood, J. R., & Self Davies, Z. T. (2017). Work minimization accounts for footfall phasing in slow quadrupedal gaits. eLife, 6, e29495. https://doi.org/10.7554/eLife.29495.001

Quadrupeds, like most bipeds, tend to walk with an even left/right footfall timing. However, the phasing between hind and forelimbs shows considerable variation. Here, we account for this variation by modeling and explaining the influence of hind-for... Read More about Work minimization accounts for footfall phasing in slow quadrupedal gaits.

Sost deficiency does not alter bone’s lacunar or vascular porosity in mice (2017)
Journal Article
Mosey, H., Núñez, J. A., Goring, A., Clarkin, C. E., Staines, K. A., Lee, P. D., Pitsillides, A. A., & Javaheri, B. (2017). Sost deficiency does not alter bone’s lacunar or vascular porosity in mice. Frontiers in Materials, 4(27), https://doi.org/10.3389/fmats.2017.00027

SCLEROSTIN (Sost) is expressed predominantly in osteocytes acting as a negative regulator of bone formation. In humans, mutations in the SOST gene lead to skeletal overgrowth and increased bone mineral density, suggesting that SCLEROSTIN is a key reg... Read More about Sost deficiency does not alter bone’s lacunar or vascular porosity in mice.

Infections by human gastrointestinal helminths are associated with changes in faecal microbiota diversity and composition (2017)
Journal Article
Jenkins, T. P., Rathnayaka, Y., Perera, P. K., Peachey, L. E., Nolan, M. J., Krause, L., Rajakaruna, R. S., & Cantacessi, C. (2017). Infections by human gastrointestinal helminths are associated with changes in faecal microbiota diversity and composition. PLoS ONE, 12(9), e0184719. https://doi.org/10.1371/journal.pone.0184719

Investigations of the impact that patent infections by soil-transmitted gastrointestinal nematode parasites exert on the composition of the host gut commensal flora are attracting growing interest by the scientific community. However, information col... Read More about Infections by human gastrointestinal helminths are associated with changes in faecal microbiota diversity and composition.

Neospora caninum and Bovine Neosporosis: Current Vaccine Research (2017)
Journal Article
Marugan-Hernandez, V. (2017). Neospora caninum and Bovine Neosporosis: Current Vaccine Research. Journal of Comparative Pathology, 157(2-3), 193-200. https://doi.org/10.1016/j.jcpa.2017.08.001

Neospora caninum, a tissue cyst-forming parasite, is the causative agent of bovine neosporosis. It is considered to be one of the most important transmissible causes of reproductive failure in cattle; abortion and neonatal mortality result in signifi... Read More about Neospora caninum and Bovine Neosporosis: Current Vaccine Research.

Improving Student Engagement in Veterinary Business Studies (2017)
Journal Article
Armitage-Chan, E., & Jackson, E. L. (2017). Improving Student Engagement in Veterinary Business Studies. Journal of Veterinary Medical Education, 45(2), 204-212. https://doi.org/10.3138/jvme.0816-137r1

In a densely packed veterinary curriculum, students may find it particularly challenging to engage in the less overtly clinical subjects, yet pressure from industry and an increasingly competitive employment market necessitate improved veterinary stu... Read More about Improving Student Engagement in Veterinary Business Studies.

The Hidden Curriculum of Veterinary Education: Mediators and Moderators of Its Effects (2017)
Journal Article
Roder, C. A., & May, S. A. (2017). The Hidden Curriculum of Veterinary Education: Mediators and Moderators of Its Effects. Journal of Veterinary Medical Education, 44(3), 542-551. https://doi.org/10.3138/jvme.0416-082

The “hidden curriculum” has long been supposed to have an effect on students' learning during their clinical education, and in particular in shaping their ideas of what it means to be a professional. Despite this, there has been little evidence linki... Read More about The Hidden Curriculum of Veterinary Education: Mediators and Moderators of Its Effects.

Dogs with macroadenomas have lower body temperature and heart rate than dogs with microadenomas (2017)
Journal Article
Benchekroun, G., Desquilbet, L., Herrtage, M. E., Jeffery, N. D., Rosenberg, D., & Granger, N. (2017). Dogs with macroadenomas have lower body temperature and heart rate than dogs with microadenomas. The Veterinary Journal, 227, 42-45. https://doi.org/10.1016/j.tvjl.2017.08.007

Pituitary macroadenomas compress the hypothalamus, which partly regulates heart rate and body temperature. The aim of this study was to investigate whether heart rate and/or body temperature could aid in clinically differentiating dogs with macroaden... Read More about Dogs with macroadenomas have lower body temperature and heart rate than dogs with microadenomas.