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Isolation and identification of Acinetobacter spp. from healthy canine skin (2018)
Journal Article
Mitchell, K. E., Turton, J. F., & Lloyd, D. H. (2018). Isolation and identification of Acinetobacter spp. from healthy canine skin. Veterinary Dermatology, 29(3), 240+. https://doi.org/10.1111/vde.12528

Acinetobacter species can exhibit widespread resistance to antimicrobial agents. They are already recognized as important nosocomial pathogens of humans, but are becoming increasingly recognized in opportunistic infections of animals. This study aime... Read More about Isolation and identification of Acinetobacter spp. from healthy canine skin.

The Lancet Countdown on health and climate change: from 25 years of inaction to a global transformation for public health (2018)
Journal Article
Watts, N., Amann, M., Ayeb-Karlsson, S., Belesova, K., Bouley, T., Boykoff, M., Byass, P., Cai, W. J., Campbell-Lendrum, D., Chambers, J., Cox, P. M., Daly, M., Dasandi, N., Davies, M., Depledge, M., Depoux, A., Dominguez-Salas, P., Drummond, P., Ekins, P., Flahault, A., …Costello, A. (2018). The Lancet Countdown on health and climate change: from 25 years of inaction to a global transformation for public health. https://doi.org/10.1016/S0140-6736%2817%2932464-9

Modelling the economic efficiency of using different strategies to control Porcine Reproductive & Respiratory Syndrome at herd level (2018)
Journal Article
Nathues, H., Alarcon, P., Rushton, J., Jolie, R., Fiebig, K., Jimenez, M., Geurts, V., & Nathues, C. (2018). Modelling the economic efficiency of using different strategies to control Porcine Reproductive & Respiratory Syndrome at herd level. Preventive Veterinary Medicine, 152, 89-102. https://doi.org/10.1016/j.prevetmed.2018.02.005

PRRS is among the diseases with the highest economic impact in pig production worldwide. Different strategies have been developed and applied to combat PRRS at farm level. The broad variety of available intervention strategies makes it difficult to d... Read More about Modelling the economic efficiency of using different strategies to control Porcine Reproductive & Respiratory Syndrome at herd level.

Therapeutic efficacy of microtube-embedded chondroitinase ABC in a canine clinical model of spinal cord injury (2018)
Journal Article
Hu, H. Z., Granger, N., Pai, S. B., Bellamkonda, R. V., & Jeffery, N. D. (2018). Therapeutic efficacy of microtube-embedded chondroitinase ABC in a canine clinical model of spinal cord injury. Brain, 141, 1017-1027. https://doi.org/10.1093/brain/awy007

Many hundreds of thousands of people around the world are living with the long-term consequences of spinal cord injury and they need effective new therapies. Laboratory research in experimental animals has identified a large number of potentially tra... Read More about Therapeutic efficacy of microtube-embedded chondroitinase ABC in a canine clinical model of spinal cord injury.

Quantitative risk assessment of hepatitis E virus: modelling the occurrence of viraemic pigs and the presence of the virus in organs of food safety interest (2018)
Journal Article
Crotta, M., Lavazza, A., Mateus, A. L. P., & Guitian, J. (2018). Quantitative risk assessment of hepatitis E virus: modelling the occurrence of viraemic pigs and the presence of the virus in organs of food safety interest. https://doi.org/10.1016/j.mran.2018.02.001

Hepatitis E virus (HEV) is a zoonotic pathogen with consumption of pork and derived products identified in different countries as a risk factor for human exposure to HEV. Great efforts have been made to understand the dynamics of virus transmission w... Read More about Quantitative risk assessment of hepatitis E virus: modelling the occurrence of viraemic pigs and the presence of the virus in organs of food safety interest.

Biomechanics of predator–prey arms race in lion, zebra, cheetah and impala (2018)
Journal Article
Wilson, A. M., Hubel, T. Y., Wilshin, S. D., Lowe, J. C., Lorenc, M., Dewhirst, O. P., Bartlam-Brooks, H. L. A., Diack, R. A., Bennitt, E., Golabek, K. A., Woledge, R., McNutt, J. W., Curtin, N. A., & West, T. G. (2018). Biomechanics of predator–prey arms race in lion, zebra, cheetah and impala. Nature, 554(7691), 183+. https://doi.org/10.1038/nature25479

The fastest and most manoeuvrable terrestrial animals are found in savannah habitats, where predators chase and capture running prey. Hunt outcome and success rate are critical to survival, so both predator and prey should evolve to be faster and/or... Read More about Biomechanics of predator–prey arms race in lion, zebra, cheetah and impala.

Primate modularity and evolution: first anatomical network analysis of primate head and neck musculoskeletal system (2018)
Journal Article
Powell, V., Esteve-Altava, B., Molnar, J., Villmoare, B., Pettit, A., & Diogo, R. (2018). Primate modularity and evolution: first anatomical network analysis of primate head and neck musculoskeletal system. https://doi.org/10.1038/s41598-018-20063-3

Network theory is increasingly being used to study morphological modularity and integration. Anatomical network analysis (AnNA) is a framework for quantitatively characterizing the topological organization of anatomical structures and providing an op... Read More about Primate modularity and evolution: first anatomical network analysis of primate head and neck musculoskeletal system.

Knowledge integration in One Health policy formulation, implementation and evaluation (2018)
Journal Article
Hitziger, M., Esposito, R., Canali, M., Aragrande, M., Haesler, B., & Rüegg, S. R. (2018). Knowledge integration in One Health policy formulation, implementation and evaluation. https://doi.org/10.2471/BLT.17.202705

The One Health concept covers the interrelationship between human, animal and environmental health and requires multistakeholder collaboration across many cultural, disciplinary, institutional and sectoral boundaries. Yet, the implementation of the O... Read More about Knowledge integration in One Health policy formulation, implementation and evaluation.

Bone apparent and material densities examined by cone beam computed tomography and the Archimedes technique: comparison of the two methods and their results (2018)
Journal Article
Adams, G. J., Cook, R. B., Hutchinson, J. R., & Ziopos, P. (2018). Bone apparent and material densities examined by cone beam computed tomography and the Archimedes technique: comparison of the two methods and their results. Frontiers in Mechanical Engineering, 3(23), https://doi.org/10.3389/fmech.2017.00023

An understanding of bone apparent and material densities and how they vary within bone at the organ level is of great interest in the understanding of degenerative bone conditions and for biomedical engineering applications. The densities of bone tis... Read More about Bone apparent and material densities examined by cone beam computed tomography and the Archimedes technique: comparison of the two methods and their results.

Structure and collagen crimp patterns of functionally distinct equine tendons, revealed by quantitative polarised light microscopy (qPLM) (2018)
Journal Article
Spiesz, E. M., Thorpe, C. T., Thurner, P. J., & Screen, H. R. C. (2018). Structure and collagen crimp patterns of functionally distinct equine tendons, revealed by quantitative polarised light microscopy (qPLM). Acta Biomaterialia, 70, 281-292. https://doi.org/10.1016/j.actbio.2018.01.034

Structure-function relationships in tendons are directly influenced by the arrangement of collagen fibres. However, the details of such arrangements in functionally distinct tendons remain obscure. This study demonstrates the use of quantitative pola... Read More about Structure and collagen crimp patterns of functionally distinct equine tendons, revealed by quantitative polarised light microscopy (qPLM).

Longitudinal Analysis of Quality of Life, Clinical, Radiographic, Echocardiographic, and Laboratory Variables in Dogs with Preclinical Myxomatous Mitral Valve Disease Receiving Pimobendan or Placebo: The EPIC Study (2018)
Journal Article
Boswood, A., Gordon, S. G., Häggström, J., Wess, G., Stepien, R. L., Oyama, M. A., Keene, B. W., Bonagura, J. D., MacDonald, K. A., Patteson, M., Smith, S., Fox, P. R., Sanderson, K., Woolley, R., Szatmári, V., Menaut, P., Church, W. M., O'Sullivan, M. L., Jaudon, J. P., Kresken, J.-G., …Watson, P. (2018). Longitudinal Analysis of Quality of Life, Clinical, Radiographic, Echocardiographic, and Laboratory Variables in Dogs with Preclinical Myxomatous Mitral Valve Disease Receiving Pimobendan or Placebo: The EPIC Study. Journal of Veterinary Internal Medicine, 32(1), 72-85. https://doi.org/10.1111/jvim.14885

Background: Changes in clinical variables associated with the administration of pimobendan to dogs with preclinical myxomatous mitral valve disease (MMVD) and cardiomegaly have not been described.

Objectives: To investigate the effect of pimobenda... Read More about Longitudinal Analysis of Quality of Life, Clinical, Radiographic, Echocardiographic, and Laboratory Variables in Dogs with Preclinical Myxomatous Mitral Valve Disease Receiving Pimobendan or Placebo: The EPIC Study.

Pharmacokinetic–pharmacodynamic integration and modelling of oxytetracycline for the calf pathogens Mannheimia haemolytica and Pasteurella multocida (2018)
Journal Article
Lees, P., Potter, T., Pelligand, L., & Toutain, P. L. (2018). Pharmacokinetic–pharmacodynamic integration and modelling of oxytetracycline for the calf pathogens Mannheimia haemolytica and Pasteurella multocida. Journal of Veterinary Pharmacology and Therapeutics, 41(1), 28-38. https://doi.org/10.1111/jvp.12439

A calf tissue cage model was used to study the pharmacokinetics (PK) and pharmacodynamics (PD) of oxytetracycline in serum, inflamed (exudate) and noninflamed (transudate) tissue cage fluids. After intramuscular administration, the PK was characteriz... Read More about Pharmacokinetic–pharmacodynamic integration and modelling of oxytetracycline for the calf pathogens Mannheimia haemolytica and Pasteurella multocida.

Retrospective study of more than 9000 feline cutaneous tumours in the UK: 2006–2013 (2018)
Journal Article
Ho, N. T., Smith, K. C., & Dobromylskyj, M. J. (2018). Retrospective study of more than 9000 feline cutaneous tumours in the UK: 2006–2013. Journal of Feline Medicine and Surgery, 20(2), 128-134. https://doi.org/10.1177/1098612X17699477

The aim of the study was to utilise a large database available from a UK-based, commercial veterinary diagnostic laboratory to ascertain the prevalence of different forms of cutaneous neoplasia within the feline population, and to detect any breed, s... Read More about Retrospective study of more than 9000 feline cutaneous tumours in the UK: 2006–2013.

Prospective evaluation of a protocol for transitioning porcine lente insulintreated diabetic cats to human recombinant protamine zinc insulin (2018)
Journal Article
Gostelow, R., Hazuchova, K., Scudder, C., Forcada, Y., Church, D. B., & Niessen, S. J. M. (2018). Prospective evaluation of a protocol for transitioning porcine lente insulintreated diabetic cats to human recombinant protamine zinc insulin. Journal of Feline Medicine and Surgery, 20(2), 114-121. https://doi.org/10.1177/1098612X17697482

Objectives The objective was to evaluate a nadir-led protocol for transitioning porcine lente insulin suspension (PLIS)-treated diabetic cats onto human recombinant protamine zinc insulin (PZIR).

Methods Recently diagnosed (

Behavioural and physiological responses of laying hens to automated monitoring equipment (2018)
Journal Article
Buijs, S., Booth, F., Richards, G., McGaughey, L., Nicol, C. J., Edgar, J., & Tarlton, J. F. (2018). Behavioural and physiological responses of laying hens to automated monitoring equipment. Applied Animal Behaviour Science, 199, 17-23. https://doi.org/10.1016/j.applanim.2017.10.017

Automated monitoring of behaviour can offer a wealth of information in circumstances where observing behaviour is difficult or time consuming. However, this often requires attaching monitoring devices to the animal which can alter behaviour, potentia... Read More about Behavioural and physiological responses of laying hens to automated monitoring equipment.

Hepatic acute phase response protects the brain from focal inflammation during postnatal window of susceptibility (2018)
Journal Article
Sá-Pereira, I., Roodselaar, J., Couch, Y., Consentino Kronka Sosthenes, M., Evans, M. C., Anthony, D. C., & Stolp, H. B. (2018). Hepatic acute phase response protects the brain from focal inflammation during postnatal window of susceptibility. Brain, Behavior, and Immunity, https://doi.org/10.1016/j.bbi.2018.01.008

Perinatal inflammation is known to contribute to neurodevelopmental diseases. Animal models of perinatal inflammation have revealed that the inflammatory response within the brain is age dependent, but the regulators of this variation remain unclear.... Read More about Hepatic acute phase response protects the brain from focal inflammation during postnatal window of susceptibility.

Construction of two whole genome radiation hybrid panels for dromedary (Camelus dromedarius): 5000RAD and 15000RAD (2018)
Journal Article
Perelman, P. L., Pichler, R., Gaggl, A., Larkin, D. M., Raudsepp, T., Alshanbari, F., Holl, H. M., Brooks, S. A., Burger, P. A., & Periasamy, K. (2018). Construction of two whole genome radiation hybrid panels for dromedary (Camelus dromedarius): 5000RAD and 15000RAD. Scientific Reports, 8(1), https://doi.org/10.1038/s41598-018-20223-5

The availability of genomic resources including linkage information for camelids has been very limited. Here, we describe the construction of a set of two radiation hybrid (RH) panels (5000RAD and 15000RAD) for the dromedary (Camelus dromedarius) as... Read More about Construction of two whole genome radiation hybrid panels for dromedary (Camelus dromedarius): 5000RAD and 15000RAD.

Multi-tasking Sulf1/Sulf2 enzymes do not only facilitate extracellular cell signalling but also participate in cell cycle related nuclear events (2018)
Journal Article
Krishnakumar, K., Chakravorty, I., Foy, W., Allen, S., Justo, T., Mukherjee, A., & Dhoot, G. K. (2018). Multi-tasking Sulf1/Sulf2 enzymes do not only facilitate extracellular cell signalling but also participate in cell cycle related nuclear events. Experimental Cell Research, https://doi.org/10.1016/j.yexcr.2018.01.022

This study demonstrates highly dynamic spatial and temporal pattern of SULF1/SULF2 expression in a number of neuronal cell types growing in normal culture medium that included their transient nuclear mobilisation. Their nuclear translocation became p... Read More about Multi-tasking Sulf1/Sulf2 enzymes do not only facilitate extracellular cell signalling but also participate in cell cycle related nuclear events.