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All Outputs (417)

Isolation and characterization of bacteriophages active against methicillin-resistant Staphylococcus pseudintermedius (2019)
Journal Article
Moodley, A., Kot, W., Nälgård, S., Jakociune, D., Neve, H., Hansen, L. H., …Vogensen, F. K. (2019). Isolation and characterization of bacteriophages active against methicillin-resistant Staphylococcus pseudintermedius. Research in Veterinary Science, 122, 81-85. https://doi.org/10.1016/j.rvsc.2018.11.008

We aimed to isolate and characterize bacteriophages (phages) with preferential activity against methicillin-resistant Staphylococcus pseudintermedius (MRSP), a multidrug-resistant canine pathogen. Four phages were isolated from canine faeces using tw... Read More about Isolation and characterization of bacteriophages active against methicillin-resistant Staphylococcus pseudintermedius.

Visitor effects on zoo-housed Sulawesi crested macaque (Macaca nigra) behaviour: Can signs with ‘watching eyes’ requesting quietness help? (2019)
Journal Article
Dancer, A. M. M., & Burn, C. C. (2019). Visitor effects on zoo-housed Sulawesi crested macaque (Macaca nigra) behaviour: Can signs with ‘watching eyes’ requesting quietness help?. Applied Animal Behaviour Science, 211, 88-94. https://doi.org/10.1016/j.applanim.2018.12.005

Visiting public can cause changes in the behaviour of zoo-housed primates. These effects, if indicative of stress, can be of welfare concern. However, few options to mitigate visitor effects through modulating visitor behaviour have been explored. He... Read More about Visitor effects on zoo-housed Sulawesi crested macaque (Macaca nigra) behaviour: Can signs with ‘watching eyes’ requesting quietness help?.

Clinical presentation, diagnostic findings, prognostic factors, treatment and outcome in dogs with meningoencephalomyelitis of unknown origin: A review (2019)
Journal Article
Cornelis, I., Van Ham, L., Gielen, I., De Decker, S., & Bhatti, S. F. M. (2019). Clinical presentation, diagnostic findings, prognostic factors, treatment and outcome in dogs with meningoencephalomyelitis of unknown origin: A review. https://doi.org/10.1016/j.tvjl.2018.12.007

Meningoencephalomyelitis of unknown origin (MUO) encompasses a group of idiopathic, most likely immune mediated, inflammatory central nervous system diseases that cause clinical, diagnostic and treatment challenges to veterinary neurologists. Clinica... Read More about Clinical presentation, diagnostic findings, prognostic factors, treatment and outcome in dogs with meningoencephalomyelitis of unknown origin: A review.

Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment (2019)
Journal Article
Betts, C. A., McClorey, G., Healicon, R., Hammond, S. M., Manzano, R., Muses, S., …Wood, M. J. (2019). Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment. Human Molecular Genetics, 28(3), 396-406. https://doi.org/10.1093/hmg/ddy346

Duchenne muscular dystrophy (DMD) is caused by loss of dystrophin protein, leading to progressive muscle weakness and premature death due to respiratory and/or cardiac complications. Cardiac involvement is characterized by progressive dilated cardiom... Read More about Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment.

Clinical comparison of two techniques of brachial plexus block for forelimb surgery in dogs (2019)
Journal Article
Benigni, L., Lafuente, M. P., & Viscasillas, J. (2019). Clinical comparison of two techniques of brachial plexus block for forelimb surgery in dogs. https://doi.org/10.1016/j.tvjl.2018.12.001

The objective of this study was to compare two different local anaesthesia techniques for intraoperative analgesia in dogs undergoing surgical procedures distal to the mid humeral diaphysis. Thirty-two dogs were divided into two groups: the US group... Read More about Clinical comparison of two techniques of brachial plexus block for forelimb surgery in dogs.

Optimising the detectability of H5N1 and H5N6 highly pathogenic avian influenza viruses in Vietnamese live-bird markets (2019)
Journal Article
Vergne, T., Meyer, A., Long, P. T., Elkholly, D. A., Inui, K., Padungtod, P., …Pfeiffer, D. U. (2019). Optimising the detectability of H5N1 and H5N6 highly pathogenic avian influenza viruses in Vietnamese live-bird markets. https://doi.org/10.1038/s41598-018-37616-1

Live bird markets (LBMs) are major targets for avian influenza virus (AIV) surveillance programmes. While sampling the LBM environment has become a widely used alternative to the labour-intensive sampling of live poultry, the design of surveillance p... Read More about Optimising the detectability of H5N1 and H5N6 highly pathogenic avian influenza viruses in Vietnamese live-bird markets.

Uncooked fish consumption among those at risk of Opisthorchis viverrini infection in central Thailand (2019)
Journal Article
Suwannahitatorn, P., Webster, J. P., Riley, S., Mungthin, M., & Donnelly, C. A. (2019). Uncooked fish consumption among those at risk of Opisthorchis viverrini infection in central Thailand. PLoS ONE, 14(1), e0211540. https://doi.org/10.1371/journal.pone.0211540

In contrast to northern and northeastern Thailand, central Thailand was believed not to be endemic for Opisthorchis viverrini (OV). Fieldwork conducted in a rural area of central Thailand revealed that the prevalence and incidence were relatively hig... Read More about Uncooked fish consumption among those at risk of Opisthorchis viverrini infection in central Thailand.

Visual outcome following phacoemulsification in English Cocker Spaniels with suspected progressive retinal atrophy: A retrospective multicenter study of 54 cases (2002-2017) (2019)
Journal Article
Koll, S., Enache, A., Fenollosa-Romero, E., Chang, Y. M., Busse, C., Oliver, J., …Matas Riera, M. (2019). Visual outcome following phacoemulsification in English Cocker Spaniels with suspected progressive retinal atrophy: A retrospective multicenter study of 54 cases (2002-2017). Veterinary Ophthalmology, https://doi.org/10.1111/vop.12627

Identification of qPCR reference genes suitable for normalizing gene expression in the mdx mouse model of Duchenne muscular dystrophy (2019)
Journal Article
Hildyard, J. C. W., Finch, A. M., & Wells, D. J. (2019). Identification of qPCR reference genes suitable for normalizing gene expression in the mdx mouse model of Duchenne muscular dystrophy. PLoS ONE, 14(1), e0211384. https://doi.org/10.1371/journal.pone.0211384

The mdx mouse is the most widely-used animal model of the human disease Duchenne muscular dystrophy, and quantitative PCR analysis of gene expression in the muscles of this animal plays a key role in the study of pathogenesis and disease progression... Read More about Identification of qPCR reference genes suitable for normalizing gene expression in the mdx mouse model of Duchenne muscular dystrophy.

Venous identity requires BMP signalling through ALK3 (2019)
Journal Article
Neal, A., Nornes, S., Payne, S., Wallace, M. D., Fritzsche, M., Louphrasitthiphol, P., …De Val, S. (2019). Venous identity requires BMP signalling through ALK3. Nature Communications, 10(1), https://doi.org/10.1038/s41467-019-08315-w

Venous endothelial cells are molecularly and functionally distinct from their arterial counterparts. Although veins are often considered the default endothelial state, genetic manipulations can modulate both acquisition and loss of venous fate, sugge... Read More about Venous identity requires BMP signalling through ALK3.

Impact of Eimeria tenella coinfection on Campylobacter jejuni colonisation of the chicken (2019)
Journal Article
Macdonald, S. E., Van Diemen, P. M., Martineau, H., Stevens, M. P., Tomley, F. M., Stabler, R. A., & Blake, D. P. (2019). Impact of Eimeria tenella coinfection on Campylobacter jejuni colonisation of the chicken. Infection and Immunity, 87(2), https://doi.org/10.1128/IAI.00772-18

Eimeria tenella can cause the disease coccidiosis in chickens. The direct and often detrimental impact of this parasite on chicken health, welfare and productivity is well recognised, however less is known about the secondary effects infection may ha... Read More about Impact of Eimeria tenella coinfection on Campylobacter jejuni colonisation of the chicken.

LIPID MEDIATORS IN IMMUNE REGULATION AND RESOLUTION (2019)
Journal Article
Gilroy, D. W., & Bishop-Bailey, D. (2019). LIPID MEDIATORS IN IMMUNE REGULATION AND RESOLUTION. British Journal of Pharmacology, 176(8), https://doi.org/10.1111/bph.14587

We are all too familiar with the events that follow a bee sting – heat, redness, swelling and pain. These are Celsus’ four cardinal signs of inflammation that are driven by very well defined signals and hormones; in fact targeting the factors that dr... Read More about LIPID MEDIATORS IN IMMUNE REGULATION AND RESOLUTION.

Backyard poultry production in Chile: animal health management and contribution to food access in an upper middle-income country (2019)
Journal Article
Di Pillo, F., Anríquez, G., Alarcón, P., Jimenez-Bluhm, P., Galdames, P., Nieto, V., …Hamilton-West, C. (2019). Backyard poultry production in Chile: animal health management and contribution to food access in an upper middle-income country. Preventive Veterinary Medicine, 164, 41-48. https://doi.org/10.1016/j.prevetmed.2019.01.008

Backyard production systems (BPS) that involve poultry are a good way to improve food security and poverty alleviation. Few studies have been carried out to quantify the contribution of poultry production to these households and the constraints they... Read More about Backyard poultry production in Chile: animal health management and contribution to food access in an upper middle-income country.

Comparison of in vitro static and dynamic assays to evaluate the efficacy of an antimicrobial drug combination against Staphylococcus aureus (2019)
Journal Article
Broussou, D. C., Toutain, P., Woehrlé, F., El Garch, F., Bousquet-Mélou, A., & Ferran, A. A. (2019). Comparison of in vitro static and dynamic assays to evaluate the efficacy of an antimicrobial drug combination against Staphylococcus aureus. PLoS ONE, 14(1), e0211214. https://doi.org/10.1371/journal.pone.0211214

An easily implementable strategy to reduce treatment failures in severe bacterial infections is to combine already available antibiotics. However, most in vitro combination assays are performed by exposing standard bacterial inocula to constant conce... Read More about Comparison of in vitro static and dynamic assays to evaluate the efficacy of an antimicrobial drug combination against Staphylococcus aureus.

A retrospective study of mortality in Eurasian lynx (Lynx lynx) in UK zoos (2019)
Journal Article
Heaver, J., & Waters, M. (2019). A retrospective study of mortality in Eurasian lynx (Lynx lynx) in UK zoos. Zoo Biology, https://doi.org/10.1002/zoo.21476

IUCN currently classifies the Eurasian lynx (Lynx lynx) as “Least Concern,” however, across its six to nine subspecies, some isolated populations are classified as “Endangered” or “Critically Endangered.” Despite this and the species’ relative ubiqui... Read More about A retrospective study of mortality in Eurasian lynx (Lynx lynx) in UK zoos.

Leishmaniosis in a dog with no travel history outside of the UK (2019)
Journal Article
McKenna, M., Attipa, C., Tasker, S., & Augusto, M. (2019). Leishmaniosis in a dog with no travel history outside of the UK. Veterinary Record, https://doi.org/10.1136/vr.105157

A 3-year-old male neutered Shih Tzu cross was presented for investigation of a three-week history of weight loss, seborrhoea, vomiting and diarrhoea. Initial clinicopathological findings included pancytopenia, mild hypercalcaemia and marked hyperglob... Read More about Leishmaniosis in a dog with no travel history outside of the UK.

Sost haploinsufficiency provokes peracute lethal cardiac tamponade without rescuing the osteopenia in a mouse model of excess glucocorticoids (2019)
Journal Article
Javaheri, B., Herbert, E., Hopkinson, M., Al-Jazzar, A., & Pitsillides, A. A. (2019). Sost haploinsufficiency provokes peracute lethal cardiac tamponade without rescuing the osteopenia in a mouse model of excess glucocorticoids. American Journal of Pathology, 189(4), 753-761. https://doi.org/10.1016/j.ajpath.2018.12.007

Glucocorticoid-induced secondary osteoporosis is the most predictable side-effect of this anti-inflammatory. One of the main mechanisms by which glucocorticoids achieve such deleterious outcome in bone is by antagonizing Wnt/β-catenin signalling. Scl... Read More about Sost haploinsufficiency provokes peracute lethal cardiac tamponade without rescuing the osteopenia in a mouse model of excess glucocorticoids.