All Outputs (506)

Assessing the impact of COVID-19 border restrictions on dengue transmission in Yunnan Province, China: an observational epidemiological and phylogenetic analysis (2021)
Journal Article
Li, N., Feng, Y., Vrancken, B., Chen, Y., Dong, L., Yang, Q., …Tian, H. (2021). Assessing the impact of COVID-19 border restrictions on dengue transmission in Yunnan Province, China: an observational epidemiological and phylogenetic analysis. The Lancet Regional Health, 14, https://doi.org/10.1016/j.lanwpc.2021.100259

Background: In response to the COVID-19 pandemic, China implemented strict restrictions on cross-border travel to prevent disease importation. Yunnan, a Chinese province that borders dengue-endemic countries in Southeast Asia, experienced unprecedent... Read More about Assessing the impact of COVID-19 border restrictions on dengue transmission in Yunnan Province, China: an observational epidemiological and phylogenetic analysis.

Avian influenza transmission risk along live poultry trading networks in Bangladesh (2021)
Journal Article
Moyen, N., Hoque, M., Mahmud, R., Hasan, M., Sarkar, S., Biswas, P., …Fournie, G. (2021). Avian influenza transmission risk along live poultry trading networks in Bangladesh. Scientific Reports, 11(1), https://doi.org/10.1038/s41598-021-98989-4

Live animal markets are known hotspots of zoonotic disease emergence. To mitigate those risks, we need to understand how networks shaped by trading practices influence disease spread. Yet, those practices are rarely recorded in high-risk settings. Th... Read More about Avian influenza transmission risk along live poultry trading networks in Bangladesh.

Accuracy of history, physical examination, cardiac biomarkers, and biochemical variables in identifying dogs with stage B2 degenerative mitral valve disease (2021)
Journal Article
Wilshaw, J., Rosenthal, S., Wess, G., Dickson, D., Bevilacqua, L., Dutton, E., …Boswood, A. (2021). Accuracy of history, physical examination, cardiac biomarkers, and biochemical variables in identifying dogs with stage B2 degenerative mitral valve disease. Journal of Veterinary Internal Medicine, 35(2), 755-770. https://doi.org/10.1111/jvim.16083

Background Treatment is indicated in dogs with preclinical degenerative mitral valve disease (DMVD) and cardiomegaly (stage B2). This is best diagnosed using echocardiography; however, relying upon this limits access to accurate diagnosis. Objectives... Read More about Accuracy of history, physical examination, cardiac biomarkers, and biochemical variables in identifying dogs with stage B2 degenerative mitral valve disease.

The role of livestock movements in the spread of Rift Valley fever virus in animals and humans in Mayotte, 2018-19 (2021)
Journal Article
Kim, Y., Metras, R., Dommergues, L., Youssouffi, C., Combo, S., Le Godais, G., …Fournie, G. (2021). The role of livestock movements in the spread of Rift Valley fever virus in animals and humans in Mayotte, 2018-19. PLoS Neglected Tropical Diseases, 15(3), https://doi.org/10.1371/journal.pntd.0009202

Rift Valley fever (RVF) is a vector-borne viral disease of major animal and public health importance. In 2018-19, it caused an epidemic in both livestock and human populations of the island of Mayotte. Using Bayesian modelling approaches, we assessed... Read More about The role of livestock movements in the spread of Rift Valley fever virus in animals and humans in Mayotte, 2018-19.

Effects of pimobendan in cats with hypertrophic cardiomyopathy and recent congestive heart failure: Results of a prospective, double-blind, randomized, nonpivotal, exploratory field study (2021)
Journal Article
Schober, K., Rush, J., Fuentes, V., Glaus, T., Summerfield, N., Wright, K., …Mohren, N. (2021). Effects of pimobendan in cats with hypertrophic cardiomyopathy and recent congestive heart failure: Results of a prospective, double-blind, randomized, nonpivotal, exploratory field study. Journal of Internal Medicine, 35(2), 789-800. https://doi.org/10.1111/jvim.16054

Background The benefits of pimobendan in the treatment of congestive heart failure (CHF) in cats with hypertrophic cardiomyopathy (HCM) have not been evaluated prospectively. Hypothesis/Objectives To investigate the effects of pimobendan in cats with... Read More about Effects of pimobendan in cats with hypertrophic cardiomyopathy and recent congestive heart failure: Results of a prospective, double-blind, randomized, nonpivotal, exploratory field study.

Effect of a 2+1 schedule of ten-valent versus 13-valent pneumococcal conjugate vaccine on pneumococcal carriage: Results from a randomised controlled trial in Vietnam (2021)
Journal Article
Temple, B., Nation, M., Dai, V., Beissbarth, J., Bright, K., Dunne, E., …Mulholland, K. (2021). Effect of a 2+1 schedule of ten-valent versus 13-valent pneumococcal conjugate vaccine on pneumococcal carriage: Results from a randomised controlled trial in Vietnam. Vaccine, 39(16), 2303-2310. https://doi.org/10.1016/j.vaccine.2021.02.043

Background: Pneumococcal conjugate vaccines (PCVs) generate herd protection by reducing nasopharyngeal (NP) carriage. Two PCVs, PCV10 and PCV13, have been in use for over a decade, yet there are few data comparing their impact on carriage. Here we re... Read More about Effect of a 2+1 schedule of ten-valent versus 13-valent pneumococcal conjugate vaccine on pneumococcal carriage: Results from a randomised controlled trial in Vietnam.

Epidemic disease risks and implications for Veterinary Services (2021)
Journal Article
Jost, C., Machalaba, C., Karesh, W., McDermott, J., Beltran-Alcrudo, D., Bett, B., …Pfeiffer, D. (2021). Epidemic disease risks and implications for Veterinary Services. Scientific & Technical Review, 40(2), 497-509. https://doi.org/10.20506/rst.40.2.3240

Growth in the livestock sector is associated with heightened risk for epidemic diseases. The increasing spillover of new diseases from wildlife is being driven by wide-scale anthropogenic changes allowing for more frequent and closer wildlife-human a... Read More about Epidemic disease risks and implications for Veterinary Services.

Direct and indirect effects of 13-valent pneumococcal conjugate vaccine on pneumococcal carriage in children hospitalised with pneumonia from formal and informal settlements in Mongolia: an observational study (2021)
Journal Article
PneuCAPTIVE Mongolia Res Grp, Chan, J., Mungun, T., Batsaixan, P., Ulziibayar, M., Suuri, B., …Russell, F. (2021). Direct and indirect effects of 13-valent pneumococcal conjugate vaccine on pneumococcal carriage in children hospitalised with pneumonia from formal and informal settlements in Mongolia: an observational study. The Lancet Regional Health, 15, https://doi.org/10.1016/j.lanwpc.2021.100231

Background: Within Ulaanbaatar, Mongolia, risk factors for pneumonia are concentrated among children living in informal settlements comprised of temporary shelters (gers). We used pneumococcal carriage surveillance among children from formal and info... Read More about Direct and indirect effects of 13-valent pneumococcal conjugate vaccine on pneumococcal carriage in children hospitalised with pneumonia from formal and informal settlements in Mongolia: an observational study.

Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy (2021)
Journal Article
Tajan, M., Hennequart, M., Cheung, E., Zani, F., Hock, A., Legrave, N., …Vousden, K. (2021). Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy. Nature Communications, 12(1), https://doi.org/10.1038/s41467-020-20223-y

Many tumour cells show dependence on exogenous serine and dietary serine and glycine starvation can inhibit the growth of these cancers and extend survival in mice. However, numerous mechanisms promote resistance to this therapeutic approach, includi... Read More about Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy.

Detection and characterization of carbapenem resistant Gram-negative bacilli isolates recovered from hospitalized patients at Soba University Hospital, Sudan (2021)
Journal Article
Elbadawi, H., Elhag, K., Mahgoub, E., Altayb, H., Ntoumi, F., Elton, L., …Hamid, M. (2021). Detection and characterization of carbapenem resistant Gram-negative bacilli isolates recovered from hospitalized patients at Soba University Hospital, Sudan. BMC Microbiology, 21(1), https://doi.org/10.1186/s12866-021-02133-1

Background: Antimicrobial resistance (AMR) poses a complex threat to global health security and universal health coverage. Recently, nosocomial infections with carbapenemase-producing Gram-negative bacilli (GNB) is increasing worldwide. We report the... Read More about Detection and characterization of carbapenem resistant Gram-negative bacilli isolates recovered from hospitalized patients at Soba University Hospital, Sudan.

Predictors of free-roaming domestic dogs' contact network centrality and their relevance for rabies control (2021)
Journal Article
Warembourg, C., Fournie, G., Abakar, M., Alvarez, D., Berger-Gonzalez, M., Odoch, T., …Durr, S. (2021). Predictors of free-roaming domestic dogs' contact network centrality and their relevance for rabies control. Scientific Reports, 11(1), https://doi.org/10.1038/s41598-021-92308-7

Free roaming domestic dogs (FRDD) are the main vectors for rabies transmission to humans worldwide. To eradicate rabies from a dog population, current recommendations focus on random vaccination with at least 70% coverage. Studies suggest that target... Read More about Predictors of free-roaming domestic dogs' contact network centrality and their relevance for rabies control.

Micellar Antibiotics of Bacillus (2021)
Journal Article
Ferreira, W., Hong, H., Hess, M., Adams, J., Wood, H., Bakun, K., …Cutting, S. (2021). Micellar Antibiotics of Bacillus. Pharmaceutics, 13(8), https://doi.org/10.3390/pharmaceutics13081296

Members of the Bacillus genus, particularly the "Bacillus subtilis group", are known to produce amphipathic lipopeptides with biosurfactant activity. This includes the surfactins, fengycins and iturins that have been associated with antibacterial, an... Read More about Micellar Antibiotics of Bacillus.

Whole-genome sequencing of Schistosoma mansoni reveals extensive diversity with limited selection despite mass drug administration (2021)
Journal Article
Berger, D., Crellen, T., Lamberton, P., Allan, F., Tracey, A., Noonan, J., …Cotton, J. (2021). Whole-genome sequencing of Schistosoma mansoni reveals extensive diversity with limited selection despite mass drug administration. Nature Communications, 12(1), https://doi.org/10.1038/s41467-021-24958-0

Control and elimination of the parasitic disease schistosomiasis relies on mass administration of praziquantel. Whilst these programmes reduce infection prevalence and intensity, their impact on parasite transmission and evolution is poorly understoo... Read More about Whole-genome sequencing of Schistosoma mansoni reveals extensive diversity with limited selection despite mass drug administration.

Complete Genome Sequencing of Field Isolates of Peste des Petits Ruminants Virus from Tanzania Revealed a High Nucleotide Identity with Lineage III PPR Viruses (2021)
Journal Article
Kinimi, E., Mahapatra, M., Kgotlele, T., Makange, M., Tennakoon, C., Njeumi, F., …Misinzo, G. (2021). Complete Genome Sequencing of Field Isolates of Peste des Petits Ruminants Virus from Tanzania Revealed a High Nucleotide Identity with Lineage III PPR Viruses. Animals, 11(10), https://doi.org/10.3390/ani11102976

Simple Summary:& nbsp;Peste des petits ruminants virus (PPRV) causes a highly devastating disease, peste des petits ruminants (PPR), in sheep and goats, which is targeted for global control and eradication. However, in many developing countries, acce... Read More about Complete Genome Sequencing of Field Isolates of Peste des Petits Ruminants Virus from Tanzania Revealed a High Nucleotide Identity with Lineage III PPR Viruses.

Prevalence of Streptococcus pneumoniae in conjunctival flora and association with nasopharyngeal carriage among children in a Vietnamese community (2021)
Journal Article
Mohamed, Y., Toizumi, M., Uematsu, M., Nguyen, H., Le, L., Takegata, M., …Yoshida, L. (2021). Prevalence of Streptococcus pneumoniae in conjunctival flora and association with nasopharyngeal carriage among children in a Vietnamese community. Scientific Reports, 11(1), https://doi.org/10.1038/s41598-020-79175-4

Conjunctival pneumococcal serotypes among members of a community have not been investigated well. We determined the prevalence and association of Streptococcus pneumoniae in the nasopharynx and conjunctiva among children in a community before pneumoc... Read More about Prevalence of Streptococcus pneumoniae in conjunctival flora and association with nasopharyngeal carriage among children in a Vietnamese community.

Spillover, hybridization, and persistence in schistosome transmission dynamics at the human-animal interface (2021)
Journal Article
Borlase, A., Rudge, J., Leger, E., Diouf, N., Fall, C., Diop, S., …Webster, J. (2021). Spillover, hybridization, and persistence in schistosome transmission dynamics at the human-animal interface. Proceedings of the National Academy of Sciences, 118(41), https://doi.org/10.1073/pnas.2110711118

Zoonotic spillover and hybridization of parasites are major emerging public and veterinary health concerns at the interface of infectious disease biology, evolution, and control. Schistosomiasis is a neglected tropical disease of global importance ca... Read More about Spillover, hybridization, and persistence in schistosome transmission dynamics at the human-animal interface.

Immediate effects of COVID-19 on the global dairy sector (2021)
Journal Article
Acosta, A., McCorriston, S., Nicolli, F., Venturelli, E., Wickramasinghe, U., ArceDiaz, E., …Steinfeld, H. (2021). Immediate effects of COVID-19 on the global dairy sector. Agricultural Systems, 192, https://doi.org/10.1016/j.agsy.2021.103177

CONTEXT: The emergence and rapid spread of the coronavirus disease (COVID-19) has posed an unprecedented threat to both societies and economies. The dairy sector is an example of the challenges that food supply chains have faced due to the pandemic.... Read More about Immediate effects of COVID-19 on the global dairy sector.

Characterization of genetic diversity and population structure within Staphylococcus chromogenes by multilocus sequence typing (2021)
Journal Article
Huebner, R., Mugabi, R., Hetesy, G., Fox, L., De Vliegher, S., De Visscher, A., …Sensabaugh, G. (2021). Characterization of genetic diversity and population structure within Staphylococcus chromogenes by multilocus sequence typing. PLoS ONE, 16(3), https://doi.org/10.1371/journal.pone.0243688

Staphylococcus chromogenes is a common skin commensal in cattle and has been identified as a frequent cause of bovine mastitis and intramammary infections. We have developed a seven locus Multilocus Sequence Typing (MLST) scheme for typing S. chromog... Read More about Characterization of genetic diversity and population structure within Staphylococcus chromogenes by multilocus sequence typing.

Household and animal factors associated with sheeppox and goatpox sero-prevalence and identification of high-risk areas in selected States of northern Nigeria (2021)
Journal Article
Adedeji, A., Ijoma, S., Atai, R., Dogonyaro, B., Adole, J., Maurice, N., …Limon, G. (2021). Household and animal factors associated with sheeppox and goatpox sero-prevalence and identification of high-risk areas in selected States of northern Nigeria. Preventive Veterinary Medicine, 196, https://doi.org/10.1016/j.prevetmed.2021.105473

Sheeppox and goatpox (SGP) are transboundary, highly contagious diseases affecting sheep and goats with characteristic clinical signs. SGP affect populations of small ruminants in Africa, Asia and the Middle East and, as a result, threaten farmers' l... Read More about Household and animal factors associated with sheeppox and goatpox sero-prevalence and identification of high-risk areas in selected States of northern Nigeria.

The mTOR regulated RNA-binding protein LARP1 requires PABPC1 for guided mRNA interaction (2021)
Journal Article
Smith, E., Benbahouche, N., Morris, K., Wilczynska, A., Gillen, S., Schmidt, T., …Bushell, M. (2021). The mTOR regulated RNA-binding protein LARP1 requires PABPC1 for guided mRNA interaction. Nucleic Acids Research, 49(1), 458-478. https://doi.org/10.1093/nar/gkaa1189

The mammalian target of rapamycin (mTOR) is a critical regulator of cell growth, integrating multiple signalling cues and pathways. Key among the downstream activities of mTOR is the control of the protein synthesis machinery. This is achieved, in pa... Read More about The mTOR regulated RNA-binding protein LARP1 requires PABPC1 for guided mRNA interaction.