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All Outputs (506)

Sensitivity of the Natriuretic Peptide/cGMP System to Hyperammonaemia in Rat C6 Glioma Cells and GPNT Brain Endothelial Cells (2021)
Journal Article
Regan, J., Mirczuk, S., Scudder, C., Stacey, E., Khan, S., Powles, T., …Fowkes, R. (2021). Sensitivity of the Natriuretic Peptide/cGMP System to Hyperammonaemia in Rat C6 Glioma Cells and GPNT Brain Endothelial Cells. Cells, https://doi.org/10.3390/cells10020398

C-type natriuretic peptide (CNP) is the major natriuretic peptide of the central nervous system and acts via its selective guanylyl cyclase-B (GC-B) receptor to regulate cGMP production in neurons, astrocytes and endothelial cells. CNP is implicated... Read More about Sensitivity of the Natriuretic Peptide/cGMP System to Hyperammonaemia in Rat C6 Glioma Cells and GPNT Brain Endothelial Cells.

Characterisation and mapping of the surveillance system for Antimicrobial Resistance and Antimicrobial Use in the United Kingdom (2021)
Journal Article
Bennani, H., Cornelsen, L., Stärk, K., & Häsler, B. (2021). Characterisation and mapping of the surveillance system for Antimicrobial Resistance and Antimicrobial Use in the United Kingdom. Veterinary Record, https://doi.org/10.1002/vetr.10

Background: Surveillance of antimicrobial resistance (AMR) is an essential component of any strategy to mitigate AMR and needs regular evaluation to ensure its effectiveness. A first step for any evaluation is to describe the system and context. In t... Read More about Characterisation and mapping of the surveillance system for Antimicrobial Resistance and Antimicrobial Use in the United Kingdom.

Diversity and dynamics of zoonotic pathogens within a local community of small mammals (2021)
Journal Article
Balážová, A., Nosková, E., Široký, P., Durrant, C., & Baláž, V. (2021). Diversity and dynamics of zoonotic pathogens within a local community of small mammals. Biologia, 3267–3273. https://doi.org/10.1007/s11756-021-00797-8

Small mammals are important reservoirs of multiple pathogens transmittable to humans. Rodent populations are highly dynamic, passing through multiannual cycles with densities changing in several orders of magnitude. Such variable pools of hosts shap... Read More about Diversity and dynamics of zoonotic pathogens within a local community of small mammals.

Comparative Mapping of the Macrochromosomes of Eight Avian Species Provides Further Insight into Their Phylogenetic Relationships and Avian Karyotype Evolution (2021)
Journal Article
Kiazim, L. G., O’Connor, R. E., Larkin, D. M., Romanov, M. N., Narushin, V. G., Brazhnik, E. A., & Griffin, D. K. (in press). Comparative Mapping of the Macrochromosomes of Eight Avian Species Provides Further Insight into Their Phylogenetic Relationships and Avian Karyotype Evolution. Cells, 10(2), 362. https://doi.org/10.3390/cells10020362

Pituitary Neoplasm Nomenclature Workshop: Does Adenoma Stand the Test of Time? (2021)
Journal Article
Ho, K., Fleseriu, M., Kaiser, U., Salvatori, R., Brue, T., Lopes, M. B., …Melmed, S. (2021). Pituitary Neoplasm Nomenclature Workshop: Does Adenoma Stand the Test of Time?. Journal of the Endocrine Society, 5(3), https://doi.org/10.1210/jendso/bvaa205

The WHO Classification of Endocrine Tumours designates pituitary neoplasms as adenomas. A proposed nomenclature change to pituitary neuroendocrine tumors (PitNETs) has been met with concern by some stakeholder groups. The Pituitary Society coordinate... Read More about Pituitary Neoplasm Nomenclature Workshop: Does Adenoma Stand the Test of Time?.

Spatio-temporal distribution and agroecological factors associated with canine leptospirosis in Great Britain (2021)
Journal Article
Taylor, C., Brodbelt, D. C., Dobson, B. A., Catchpole, B., O'neill, D. G., & Stevens, K. B. (2021). Spatio-temporal distribution and agroecological factors associated with canine leptospirosis in Great Britain. Preventive Veterinary Medicine, 193, https://doi.org/10.1016/j.prevetmed.2021.105407

Leptospirosis is an important global zoonotic disease that affects a wide range of mammalian species. Canine leptospirosis outbreaks have been reported after flooding (eg. in Brazil and the United States of America) suggesting an environmental associ... Read More about Spatio-temporal distribution and agroecological factors associated with canine leptospirosis in Great Britain.

Increased insulin-like growth factor 1 concentrations in a retrospective population of non-diabetic cats diagnosed with hypertrophic cardiomyopathy (2021)
Journal Article
Steele, M. M., Borgeat, K., Payne, J. R., Coss, P., Navarro-Cubas, X., Church, D. B., …Connolly, D. J. (in press). Increased insulin-like growth factor 1 concentrations in a retrospective population of non-diabetic cats diagnosed with hypertrophic cardiomyopathy. Journal of Feline Medicine and Surgery, 1098612X2098799. https://doi.org/10.1177/1098612x20987995

Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets (2021)
Journal Article
Kia, D. A., Zhang, D., Guelfi, S., Manzoni, C., Hubbard, L., Reynolds, R. H., …United Kingdom Brain Expression Consortium (UKBEC) and the International Parkinson’s Disease Genomics Consortium (IPDGC). (2021). Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets. JAMA Neurology, 78(4), 464. https://doi.org/10.1001/jamaneurol.2020.5257

IMPORTANCE Substantial genome-wide association study (GWAS) work in Parkinson disease (PD) has led to the discovery of an increasing number of loci shown reliably to be associated with increased risk of disease. Improved understanding of the underlyi... Read More about Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets.

The Nairobi Pork Value Chain: Mapping and Assessment of Governance, Challenges, and Food Safety Issues (2021)
Journal Article
Kaitibie, S., Murungi, M. K., Raghavan, M., Muloi, D. M., Fasina, F. O., Muinde, P., …Em, F. (2021). The Nairobi Pork Value Chain: Mapping and Assessment of Governance, Challenges, and Food Safety Issues. Frontiers in Veterinary Science, 8, -. https://doi.org/10.3389/fvets.2021.581376

The Nairobi pork food system is a growing livestock sub-sector which serves as a source of food and livelihood to its inhabitants. The study aimed to map Nairobi's pork value chains, assess their governance, operational challenges and their impacts o... Read More about The Nairobi Pork Value Chain: Mapping and Assessment of Governance, Challenges, and Food Safety Issues.

Systematic analysis reveals that colony housing aligns gait profiles and strengthens link between 1 histological and micro-CT bone markers in rat models of osteoarthritis 2 Short running title: Colony housing strengthens osteoarthritis research (2021)
Journal Article
Chang, Y., Menges, S., Westhof, A., Kleinschmidt-Doerr, K., Brenneis, C., Pitsillides, A. A., & Chang, Y. (in press). Systematic analysis reveals that colony housing aligns gait profiles and strengthens link between 1 histological and micro-CT bone markers in rat models of osteoarthritis 2 Short running title: Colony housing strengthens osteoarthritis research. FASEB Journal, -. https://doi.org/10.1096/fj.202002009R

Re-sensitization of Mycobacterium smegmatis to Rifampicin Using CRISPR Interference Demonstrates Its Utility for the Study of Non-essential Drug Resistance Traits (2021)
Journal Article
Kendall, S. L., Faulkner, V., Cox, A. A., Goh, S., van Bohemen, A., Gibson, A. J., …Willcocks, S. (in press). Re-sensitization of Mycobacterium smegmatis to Rifampicin Using CRISPR Interference Demonstrates Its Utility for the Study of Non-essential Drug Resistance Traits. Frontiers in Microbiology, 11, https://doi.org/10.3389/fmicb.2020.619427

A greater understanding of the genes involved in antibiotic resistance in Mycobacterium tuberculosis (Mtb) is necessary for the design of improved therapies. Clustered regularly interspaced short palindromic repeat interference (CRISPRi) has been pre... Read More about Re-sensitization of Mycobacterium smegmatis to Rifampicin Using CRISPR Interference Demonstrates Its Utility for the Study of Non-essential Drug Resistance Traits.

Dietary and Nutritional Approaches to the Management of Chronic Enteropathy in Dogs and Cats (2021)
Journal Article
Kathrani, A. (2021). Dietary and Nutritional Approaches to the Management of Chronic Enteropathy in Dogs and Cats. Veterinary Clinics of North America: Small Animal Practice, 51(1), 123-136. https://doi.org/10.1016/j.cvsm.2020.09.005

Nutrition can influence those functions of the gastrointestinal tract that can be adversely affected in chronic enteropathy, such as microbiota, mucosal immune system, intestinal permeability, and motility. Diet serves as a possible risk factor in di... Read More about Dietary and Nutritional Approaches to the Management of Chronic Enteropathy in Dogs and Cats.

Highly Pathogenic Avian Influenza Viruses at the Wild–Domestic Bird Interface in Europe: Future Directions for Research and Surveillance (2021)
Journal Article
Verhagen, J. H., Fouchier, R. A., & Lewis, N. (in press). Highly Pathogenic Avian Influenza Viruses at the Wild–Domestic Bird Interface in Europe: Future Directions for Research and Surveillance. Viruses, 13(2), 212. https://doi.org/10.3390/v13020212

Highly pathogenic avian influenza (HPAI) outbreaks in wild birds and poultry are no longer a rare phenomenon in Europe. In the past 15 years, HPAI outbreaks—in particular those caused by H5 viruses derived from the A/Goose/Guangdong/1/1996 lineage th... Read More about Highly Pathogenic Avian Influenza Viruses at the Wild–Domestic Bird Interface in Europe: Future Directions for Research and Surveillance.

A Cohort Study Risk Factor Analysis for Endemic Disease in Pre- weaned Dairy Heifer Calves (2021)
Journal Article
Johnson, K. F., Chancellor, N., & Wathes, D. C. (in press). A Cohort Study Risk Factor Analysis for Endemic Disease in Pre- weaned Dairy Heifer Calves. Animals, https://doi.org/10.3390/xxxxx

Simple Summary: Most dairy heifer calves are removed from their dam and reared on milk from birth until weaning at around nine weeks of age. During this period they are susceptible to diseases which reduce their welfare and later performance in the d... Read More about A Cohort Study Risk Factor Analysis for Endemic Disease in Pre- weaned Dairy Heifer Calves.

The Health and Behavioural Effects of Individual versus Pair Housing of Calves at Different Ages on a UK Commercial Dairy Farm (2021)
Journal Article
Mahendran, S., Blackie, N., Booth, R., & Wathes, C. The Health and Behavioural Effects of Individual versus Pair Housing of Calves at Different Ages on a UK Commercial Dairy Farm. Manuscript submitted for publication

Housing management of dairy calves is one of the factors that contributes to a successful rearing outcome. Individual housing of pre-weaned calves is thought to provide enhanced biosecurity and easier monitoring of the individual, and so remains prev... Read More about The Health and Behavioural Effects of Individual versus Pair Housing of Calves at Different Ages on a UK Commercial Dairy Farm.

“Health in” and “Health of” Social-Ecological Systems: A Practical Framework for the Management of Healthy and Resilient Agricultural and Natural Ecosystems (2021)
Journal Article
De Garine-Wichatitsky, M., Binot, A., Ward, J., Caron, A., Perrotton, A., Ross, H., …Echaubard, P. (2021). “Health in” and “Health of” Social-Ecological Systems: A Practical Framework for the Management of Healthy and Resilient Agricultural and Natural Ecosystems. Frontiers in Public Health, 8, https://doi.org/10.3389/fpubh.2020.616328

The past two decades have seen an accumulation of theoretical and empirical evidence for the interlinkages between human health and well-being, biodiversity and ecosystem services, and agriculture. The COVID-19 pandemic has highlighted the devastatin... Read More about “Health in” and “Health of” Social-Ecological Systems: A Practical Framework for the Management of Healthy and Resilient Agricultural and Natural Ecosystems.