Skip to main content

Research Repository

Advanced Search

All Outputs (134)

Emergency management of the polytrauma patient (2025)
Journal Article
O'Byrne, E., & Cole, L. (2025). Emergency management of the polytrauma patient. In Practice, 47(2), 71-79. https://doi.org/10.1002/inpr.516

Background: Polytrauma is a commonly seen emergency in veterinary practice and is defined as two or more injuries involving multiple body parts or organ systems. One or more of these injuries may be life threatening and patients can rapidly deteriora... Read More about Emergency management of the polytrauma patient.

Improvement in short-term outcome over time, in a single center embarking on a canine mitral valve repair program using a structured multidisciplinary approach (2025)
Journal Article
Brockman, D., Greensmith, T., Rossanese, M., Young, A., Carey, S., Boswood, A., Stathopoulou, T., Jimenez, C., & Cross, N. (2025). Improvement in short-term outcome over time, in a single center embarking on a canine mitral valve repair program using a structured multidisciplinary approach. Veterinary Surgery, https://doi.org/10.1111/vsu.14229

Objective: To describe a structured approach to the development of a mitral valve repair (MVR) program for dogs with myxomatous mitral valve disease (MMVD) and to document the change in short term outcome over time. Study design: Clinical prospective... Read More about Improvement in short-term outcome over time, in a single center embarking on a canine mitral valve repair program using a structured multidisciplinary approach.

Cocaine Differentially Affects Mitochondrial Function Depending on Exposure Time (2025)
Journal Article
Wattad, S., Bryant, G., Shmuel, M., Smith, H. L., Yaka, R., & Thornton, C. (in press). Cocaine Differentially Affects Mitochondrial Function Depending on Exposure Time. International Journal of Molecular Sciences, 26(5), 2131. https://doi.org/10.3390/ijms26052131

Cocaine use is a rising global concern, and increased use is accompanied by
a significant increase in people entering treatment for the first time. However, there are
still no complete therapies, and preclinical tools are necessary to both understa... Read More about Cocaine Differentially Affects Mitochondrial Function Depending on Exposure Time.

Behavioural Engagement of Holstein Friesian Dairy Cattle with Different Mounting Techniques for Salt Licks as Environmental Enrichment (2025)
Journal Article
McLaughlin, D., & Blackie, N. (2025). Behavioural Engagement of Holstein Friesian Dairy Cattle with Different Mounting Techniques for Salt Licks as Environmental Enrichment. Animals, 15(5), 701. https://doi.org/10.3390/ani15050701

With increasing numbers of dairy farms adopting zero-grazing systems, there is a growing need for indoor environmental enrichment methods. Enrichment is necessary to meet industry requirements and fulfil behavioural motivations, such as oral manipula... Read More about Behavioural Engagement of Holstein Friesian Dairy Cattle with Different Mounting Techniques for Salt Licks as Environmental Enrichment.

International Consortium to Classify Ageing-related Pathologies (ICCARP) senescence definitions: achieving international consensus (2025)
Journal Article
Short, E., Huckstepp, R., Alavian, K., Amoaku, W., Barber, T., van Beek, E., Benbow, E., Bhandari, S., Bloom, P., Cota, C., Chazot, P., Christopher, G., Demaria, M., Erusalimsky, J., Ferenbach, D., Foster, T., Gazzard, G., Glassock, R., Jamal, N., Kalaria, R., …Bentley, B. (2025). International Consortium to Classify Ageing-related Pathologies (ICCARP) senescence definitions: achieving international consensus. GeroScience, https://doi.org/10.1007/s11357-025-01509-9

Transmission dynamics of highly pathogenic avian influenza among multiple waterfowl species and backyard poultry: the impact of the stopover period (2025)
Journal Article
Llanos-Soto, S., Yaffy, D., Pavlak, M., & Ivanek, R. (2025). Transmission dynamics of highly pathogenic avian influenza among multiple waterfowl species and backyard poultry: the impact of the stopover period. Scientific Reports, 15(1), https://doi.org/10.1038/s41598-025-89827-y

Spillover of Highly Pathogenic Avian Influenza (HPAI) to backyard poultry via migratory birds threatens the poultry industry and public health. To improve the understanding of spillover events, we developed a stochastic compartmental mathematical mod... Read More about Transmission dynamics of highly pathogenic avian influenza among multiple waterfowl species and backyard poultry: the impact of the stopover period.

Engineered pulmonary artery tissues for measuring contractility, drug testing and disease modelling (2025)
Journal Article
Fellows, A., Quigley, K., Leung, V., Ainscough, A., Wilkins, M., Barnett, H., Miller, D., Mayr, M., & Wojciak-Stothard, B. (2025). Engineered pulmonary artery tissues for measuring contractility, drug testing and disease modelling. British Journal of Pharmacology, https://doi.org/10.1111/bph.17462

Background and PurposeVasoreactivity of pulmonary arteries regulates blood flow through the lungs. Excessive constriction of these vessels contributes to pulmonary arterial hypertension (PAH), a progressive and incurable condition, resulting in right... Read More about Engineered pulmonary artery tissues for measuring contractility, drug testing and disease modelling.

Behavioural Indicators of Infectious Disease in Managed Animals (2025)
Journal Article
Nicol, C. (in press). Behavioural Indicators of Infectious Disease in Managed Animals. Applied Animal Behaviour Science, https://doi.org/10.1016/j.applanim.2025.106573

Identifying reliable and valid behavioural indicators of infection in managed animals is increasingly important as the risks of emergent diseases increase alongside concomitant concerns over pathogen resistance and the environmental and safety impact... Read More about Behavioural Indicators of Infectious Disease in Managed Animals.

Artificial intelligence for modelling infectious disease epidemics (2025)
Journal Article
Kraemer, M. U. G., Tsui, L.-H., Chang, S. Y., Lytras, S., Khurana, M. P., Vanderslott, S., Bajaj, S., Scheidwasser, N., Curran-Sebastian, J. L., Semenova, E., Zhang, M., Unwin, H. J. T., Watson, O. J., Mills, C., Dasgupta, A., Ferretti, L., Scarpino, S. V., Koua, E., Morgan, O., Tegally, H., …Bhatt, S. (2025). Artificial intelligence for modelling infectious disease epidemics. Nature, 638(8051), 623-635. https://doi.org/10.1038/s41586-024-08564-w

Infectious disease threats to individual and public health are numerous, varied and frequently unexpected. Artificial intelligence (AI) and related technologies, which are already supporting human decision making in economics, medicine and social sci... Read More about Artificial intelligence for modelling infectious disease epidemics.

Comparison of Survival After Treatment of Presumed Intracranial Meningioma by Radiotherapy or Surgery in 285 Dogs (2025)
Journal Article
Geiger, R., Mankin, J., Volk, H., de Decker, S., van Asselt, N., Randhawa, K., Ehling, T., Maitz, C., Naramor, A., Coates, J., Stalin, C., Johnstone, L., Morris, J., Plessas, I., Forward, A., Garosi, L., Scarpante, E., Cherubini, G., Harcourt-Brown, T., Carrera-Justiz, S., …Jeffery, N. (2025). Comparison of Survival After Treatment of Presumed Intracranial Meningioma by Radiotherapy or Surgery in 285 Dogs. Journal of Veterinary Internal Medicine, 39(2), https://doi.org/10.1111/jvim.70011

BackgroundThe comparative effectiveness of radiotherapy and surgery for treating intracranial meningioma is unknown.ObjectivesTo compare survival after treatment of suspected intracranial meningioma by either surgery or radiotherapy.AnimalsTwo hundre... Read More about Comparison of Survival After Treatment of Presumed Intracranial Meningioma by Radiotherapy or Surgery in 285 Dogs.

Distinctive seizure signature in the first video case-control study of a naturally-occurring feline autoimmune encephalitis model (2025)
Journal Article
Binks, S., Crawford, A., Ives, E., Davison, L., Fox, H., Fower, A., Kaczmarska, A., Woodhall, M., Waters, P., Handel, A., Irani, S., Quintana, R. G., Chowdhury, F., Eriksson, S., & Pakozdy, A. (2025). Distinctive seizure signature in the first video case-control study of a naturally-occurring feline autoimmune encephalitis model. Brain, Behavior, and Immunity, https://doi.org/10.1016/j.bbi.2025.02.018

Calculation of standard bodyweights for dogs, cats, rabbits, and guinea pigs (2025)
Journal Article
O'Neill, D., Becker, S. D., Frosini, S.-M., Stapleton, L. E., Hughes, D. M., & Brodbelt, D. C. (2025). Calculation of standard bodyweights for dogs, cats, rabbits, and guinea pigs. PLoS ONE, 20(2), e0318734. https://doi.org/10.1371/journal.pone.0318734

Standard bodyweights are an essential component of calculations that summarise many
population-level measures in companion animals, including the defined daily doses for
veterinary species (DDDVet) reporting antimicrobial usage. Standard species bo... Read More about Calculation of standard bodyweights for dogs, cats, rabbits, and guinea pigs.

Evaluation of a nanoparticle influenza vaccine in the pig model (2025)
Journal Article
van Diemen, P., Lean, F., Ramsay, A., Mollett, B., Byrne, A., Núñez, A., Herbert, E., Moin, S., Crank, M., Graham, B., Kanekiyo, M., & Everett, H. (2025). Evaluation of a nanoparticle influenza vaccine in the pig model. Vaccine, 49, https://doi.org/10.1016/j.vaccine.2025.126844

Influenza A virus (IAV) infection causes substantial disease burden and vaccines capable of conferring broad immunity are lacking, necessitating frequent reformulation of seasonal vaccines. The purpose of this study was to evaluate the immunogenicity... Read More about Evaluation of a nanoparticle influenza vaccine in the pig model.

Lasting lockdown love? Problem behaviour and pandemic and non-pandemic related risk factors influencing the owner-dog relationship in a UK cohort of dogs reaching early adulthood (2025)
Journal Article
Merritt, B. L., O’Neill, D. G., Brand, C. L., Belshaw, Z., Dale, F. C., Pegram, C. L., & Packer, R. M. A. (in press). Lasting lockdown love? Problem behaviour and pandemic and non-pandemic related risk factors influencing the owner-dog relationship in a UK cohort of dogs reaching early adulthood. PLoS ONE, 20(2), e0316166. https://doi.org/10.1371/journal.pone.0316166

The owner-dog relationship is a critical component of sustained dog ownership. Increased understanding of risk factors for weak owner-dog relationships can identify owner-dog dyads at higher risk of poor welfare outcomes, including dog relinquishment... Read More about Lasting lockdown love? Problem behaviour and pandemic and non-pandemic related risk factors influencing the owner-dog relationship in a UK cohort of dogs reaching early adulthood.

Whole genome sequencing identifies novel candidate genetic variants in canine stomatocytosis (2025)
Journal Article
Wallace, M., Falcone, S., Castillo, D., Williams, T., & Davison, L. (2025). Whole genome sequencing identifies novel candidate genetic variants in canine stomatocytosis. Gene, 149314. https://doi.org/10.1016/j.gene.2025.149314

Abstract
Stomatocytosis is a rare spectrum of red blood cell (RBC) disorders. In humans, stomatocytosis is typically caused by genetic changes in specific ion exchange and transport genes. Stomatocytosis has been identified in dogs, however the unde... Read More about Whole genome sequencing identifies novel candidate genetic variants in canine stomatocytosis.

Aberrant Right Subclavian Arteries in Dogs Have a Prevalence of 1.2% and Are More Likely to be an Incidental Finding on Computed Tomographic Studies of the Thorax (2025)
Journal Article
Jones, C., Klever, J., Cordella, A., Fouriez-Lablee, V., Watton, T., & Llabres-Diaz, F. (2025). Aberrant Right Subclavian Arteries in Dogs Have a Prevalence of 1.2% and Are More Likely to be an Incidental Finding on Computed Tomographic Studies of the Thorax. Veterinary Radiology and Ultrasound, 66(2), https://doi.org/10.1111/vru.70011

Aberrant right subclavian arteries (ARSAs) are a form of vascular ring anomaly (VRA) in dogs and the most common VRA in people. To date, there has been no large-scale study on ARSA in dogs and their potential clinical significance. For part one, a si... Read More about Aberrant Right Subclavian Arteries in Dogs Have a Prevalence of 1.2% and Are More Likely to be an Incidental Finding on Computed Tomographic Studies of the Thorax.

Extracellular matrix: Dystroglycan interactions-Roles for the dystrophin-associated glycoprotein complex in skeletal tissue dynamics (2025)
Journal Article
Hopkinson, M., & Pitsillides, A. (2025). Extracellular matrix: Dystroglycan interactions-Roles for the dystrophin-associated glycoprotein complex in skeletal tissue dynamics. International Journal of Experimental Pathology, 106(2), https://doi.org/10.1111/iep.12525

Contributions made by the dystrophin-associated glycoprotein complex (DGC) to cell-cell and cell-extracellular matrix (ECM) interactions are vital in development, homeostasis and pathobiology. This review explores how DGC functions may extend to skel... Read More about Extracellular matrix: Dystroglycan interactions-Roles for the dystrophin-associated glycoprotein complex in skeletal tissue dynamics.

Equine adult, fetal and ESC-tenocytes have differential migratory, proliferative and gene expression responses to factors upregulated in the injured tendon (2025)
Journal Article
Beaumont, R. E., Smith, E. J., David, C., Paterson, Y. Z., Faull, E., & Guest, D. J. (2025). Equine adult, fetal and ESC-tenocytes have differential migratory, proliferative and gene expression responses to factors upregulated in the injured tendon. Cells & Development, https://doi.org/10.1016/j.cdev.2025.204003

Tendon injuries are a common problem in humans and horses. There is a high re-injury rate in both species due to the poor regeneration of adult tendon and the resulting formation of scar tissue. In contrast, fetal tendon injuries undergo scarless reg... Read More about Equine adult, fetal and ESC-tenocytes have differential migratory, proliferative and gene expression responses to factors upregulated in the injured tendon.

Challenges in developing a split drive targeting dsx for the genetic control of the invasive malaria vector Anopheles stephensi (2025)
Journal Article
Larrosa-Godall, M., Ang, J., Leftwich, P., Gonzalez, E., Shackleford, L., Nevard, K., Noad, R., Anderson, M., & Alphey, L. (2025). Challenges in developing a split drive targeting dsx for the genetic control of the invasive malaria vector Anopheles stephensi. Parasites and Vectors, 18(1), https://doi.org/10.1186/s13071-025-06688-0

BackgroundAnopheles stephensi is a competent malaria vector mainly present in southern Asia and the Arabian Peninsula. Since 2012, it has invaded several countries of eastern Africa, creating an emerging risk of urban transmission. Urgent efforts are... Read More about Challenges in developing a split drive targeting dsx for the genetic control of the invasive malaria vector Anopheles stephensi.