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Outputs (423)

Species diversity of non-tuberculous mycobacteria isolated from humans, livestock and wildlife in the Serengeti ecosystem, Tanzania (2014)
Journal Article
Katale, B. Z., Mbugi, E. V., Botha, L., Keyyu, J. D., Kendall, S. L., Dockrell, H. M., Michel, A. L., Kazwala, R. R., Rweyemamu, M. M., van Helden, P., & Matee, M. I. (2014). Species diversity of non-tuberculous mycobacteria isolated from humans, livestock and wildlife in the Serengeti ecosystem, Tanzania. BMC Infectious Diseases, 14, https://doi.org/10.1186/s12879-014-0616-y

Development and Testing of a Field Diagnostic Assay for Peste des Petits Ruminants Virus (2014)
Journal Article
Baron, J., Fishbourne, E., Couacy-Hyman, E., Abubakar, M., Jones, B. A., Frost, L., Herbert, R., Chibssa, T. R., Van'T Klooster, G., Afzal, M., Ayebazibwe, C., Toye, P., Bashiruddin, J., & Baron, M. D. (2014). Development and Testing of a Field Diagnostic Assay for Peste des Petits Ruminants Virus. Transboundary and Emerging Diseases, 61(5), 390-396. https://doi.org/10.1111/tbed.12266

We have developed an immunochromatographic test for the diagnosis of peste des petits ruminants (PPR) under field conditions. The diagnostic assay has been tested in the laboratory and also under field conditions in Ivory Coast, Pakistan, Ethiopia an... Read More about Development and Testing of a Field Diagnostic Assay for Peste des Petits Ruminants Virus.

Eosinophils Are Important for Protection, Immunoregulation and Pathology during Infection with Nematode Microfilariae (2014)
Journal Article
Cadman, E. T., Thysse, K. A., Bearder, S., Cheung, A. Y. N., Johnston, A. C., Lee, J. J., & Lawrence, R. A. (2014). Eosinophils Are Important for Protection, Immunoregulation and Pathology during Infection with Nematode Microfilariae. PLoS Pathogens, 10(3), e1003988. https://doi.org/10.1371/journal.ppat.1003988

Eosinophil responses typify both allergic and parasitic helminth disease. In helminthic disease, the role of eosinophils can be both protective in immune responses and destructive in pathological responses. To investigate whether eosinophils are invo... Read More about Eosinophils Are Important for Protection, Immunoregulation and Pathology during Infection with Nematode Microfilariae.

Global Gene Expression Profiling of Myeloid Immune Cell Subsets in Response to In Vitro Challenge with Porcine Circovirus 2b (2014)
Journal Article
Mavrommatis, B., Offord, V., Patterson, R., Watson, M., Kanellos, T., Steinbach, F., Grierson, S., & Werling, D. (2014). Global Gene Expression Profiling of Myeloid Immune Cell Subsets in Response to In Vitro Challenge with Porcine Circovirus 2b. PLoS ONE, 9(3), e91081. https://doi.org/10.1371/journal.pone.0091081

Compelling evidence suggests that the early interaction between porcine circovirus 2 (PCV-2) and the innate immune system is the key event in the pathogenesis of Post-Weaning Multisystemic Wasting Syndrome (PMWS). Furthermore, PCV2 has been detected... Read More about Global Gene Expression Profiling of Myeloid Immune Cell Subsets in Response to In Vitro Challenge with Porcine Circovirus 2b.

Using Risk Assessment as Part of a Systems Approach to the Control and Prevention of HPAIV H5N1 (2014)
Journal Article
Costard, S., Fournié, G., & Pfeiffer, D. U. (2014). Using Risk Assessment as Part of a Systems Approach to the Control and Prevention of HPAIV H5N1. EcoHealth, 11(1), 36-43. https://doi.org/10.1007/s10393-014-0907-1

Since its emergence in China in 1996, highly pathogenic avian influenza virus subtype H5N1 has spread across Asia, Africa, and Europe. Countries had to promptly implement control and prevention measures. Numerous research and capacity building initia... Read More about Using Risk Assessment as Part of a Systems Approach to the Control and Prevention of HPAIV H5N1.

Prevalence and risk factors for infection of bovine tuberculosis in indigenous cattle in the Serengeti ecosystem, Tanzania (2013)
Journal Article
Katale, B. Z., Mbugi, E. V., Karimuribo, E. D., Keyyu, J. D., Kendall, S., Kibiki, G. S., Godfrey-Faussett, P., Michel, A. L., Kazwala, R. R., van Helden, P., & Matee, M. I. (2013). Prevalence and risk factors for infection of bovine tuberculosis in indigenous cattle in the Serengeti ecosystem, Tanzania. BMC Veterinary Research, 9(9), 1746-6148. https://doi.org/10.1186/1746-6148-9-267

A Global Perspective on H9N2 Avian Influenza Virus
Journal Article
Peacock, T. P., James, J., Sealy, J. E., & Iqbal, M. (in press). A Global Perspective on H9N2 Avian Influenza Virus. Viruses, 11(7), 620. https://doi.org/10.3390/v11070620

H9N2 avian influenza viruses have become globally widespread in poultry over the last two decades and represent a genuine threat both to the global poultry industry but also humans through their high rates of zoonotic infection and pandemic potential... Read More about A Global Perspective on H9N2 Avian Influenza Virus.

Ancient hybridization and adaptive introgression of an invadolysin gene in schistosome parasites
Journal Article
Platt, R. N., McDew-White, M., Le Clec'H, W., Chevalier, F. D., Allan, F., Emery, A. M., Garba, A., Hamidou, A. A., Ame, S. M., Webster, J. P., Rollinson, D., Webster, B. L., & Anderson, T. J. C. (in press). Ancient hybridization and adaptive introgression of an invadolysin gene in schistosome parasites. Molecular Biology and Evolution, 36(10), 2127-2142. https://doi.org/10.1093/molbev/msz154

Introgression among parasite species has the potential to transfer traits of biomedical importance across species boundaries. The parasitic blood fluke Schistosoma haematobium causes urogenital schistosomiasis in humans across sub-Saharan Africa. Hyb... Read More about Ancient hybridization and adaptive introgression of an invadolysin gene in schistosome parasites.

Mycoplasma hyopneumoniae evades phagocytic uptake by porcine alveolar macrophages in vitro
Journal Article
Deeney, A. S., Maglennon, G. A., Chapat, L., Crussard, S., Jolivet, E., & Rycroft, A. N. (in press). Mycoplasma hyopneumoniae evades phagocytic uptake by porcine alveolar macrophages in vitro. Veterinary Research, 50(51), https://doi.org/10.1186/s13567-019-0667-6

Mycoplasma hyopneumoniae, the agent of porcine enzootic pneumonia (EP), is able to persist in the lung tissue and evade destruction by the host for several weeks. To understand the mechanism of pathogen survival, phagocytic uptake of M. hyopneumoniae... Read More about Mycoplasma hyopneumoniae evades phagocytic uptake by porcine alveolar macrophages in vitro.

Dietary vitamin D improves performance and bone mineralisation, but increases parasite replication and compromises gut health in Eimeria infected broilers
Journal Article
Sakkas, P., Oikeh, I., Blake, D. P., Smith, S., & Kyriazakis, I. (in press). Dietary vitamin D improves performance and bone mineralisation, but increases parasite replication and compromises gut health in Eimeria infected broilers. British Journal of Nutrition, https://doi.org/10.1017/S0007114519001375

Coccidial infections may reduce fat soluble vitamin status and bone mineralisation in broiler chickens. We hypothesised that broilers infected with Eimeria maxima would benefit from increased dietary supplementation with vitamin D (vitD) or with 25-O... Read More about Dietary vitamin D improves performance and bone mineralisation, but increases parasite replication and compromises gut health in Eimeria infected broilers.

High prevalence of USA300 among clinical isolates of methicillin-resistant Staphylococcus aureus on St. Kitts and Nevis, West Indies
Journal Article
Guardabassi, L., Moodley, A., Williams, A., Stegger, M., Damborg, P., Halliday-Simmonds, I., & Butaye, P. R. (in press). High prevalence of USA300 among clinical isolates of methicillin-resistant Staphylococcus aureus on St. Kitts and Nevis, West Indies. Frontiers in Microbiology, 10, 1123. https://doi.org/10.3389/fmicb.2019.01123

Limited information is available on antimicrobial susceptibility and clonal distribution of Staphylococcus aureus in the Caribbean region. The aims of this study were to determine the prevalence of antimicrobial resistance among S. aureus isolates an... Read More about High prevalence of USA300 among clinical isolates of methicillin-resistant Staphylococcus aureus on St. Kitts and Nevis, West Indies.

The Genetics of Life and Death: Virus-Host Interactions Underpinning Resistance to African Swine Fever, a Viral Hemorrhagic Disease
Journal Article
Netherton, C. L., Connell, S., Benfield, C. T. O., & Dixon, L. K. (in press). The Genetics of Life and Death: Virus-Host Interactions Underpinning Resistance to African Swine Fever, a Viral Hemorrhagic Disease. Frontiers in Genetics, https://doi.org/10.3389/fgene.2019.00402

Pathogen transmission from wildlife hosts to genetically distinct species is a major driver of disease emergence. African swine fever virus (ASFV) persists in sub-Saharan Africa through a sylvatic cycle between warthogs and soft ticks that infest the... Read More about The Genetics of Life and Death: Virus-Host Interactions Underpinning Resistance to African Swine Fever, a Viral Hemorrhagic Disease.

The Role and Welfare of Cart Donkeys Used in Waste Management in Karachi, Pakistan
Journal Article
Shah, S. Z. A., Nawaz, Z., Nawaz, S., Carder, G., Ali, M., Soomro, N., & Compston, P. C. (in press). The Role and Welfare of Cart Donkeys Used in Waste Management in Karachi, Pakistan. Animals, 9(4), https://doi.org/10.3390/ani9040159

Equine ownership is a common income-generating strategy in Pakistan. In Karachi, donkey carts are used to transport building materials, commercial produce and garbage. This study aimed to articulate the role and welfare of donkeys used in waste manag... Read More about The Role and Welfare of Cart Donkeys Used in Waste Management in Karachi, Pakistan.

Canine Respiratory Coronavirus, Bovine Coronavirus, and Human Coronavirus OC43: Receptors and Attachment Factors
Journal Article
Szczepanski, A., Owczarek, K., Bzowska, M., Gula, K., Drebot, I., Ochman, M., Maksym, B., Rajfur, Z., Mitchell, J. A., & Pyrc, K. (in press). Canine Respiratory Coronavirus, Bovine Coronavirus, and Human Coronavirus OC43: Receptors and Attachment Factors. Viruses, 11(4), 328. https://doi.org/10.3390/v11040328

Despite high similarity of canine respiratory coronavirus (CRCoV), bovine coronavirus, (BCoV) and human coronavirus OC43 (HCoV-OC43), these viruses differ in species specificity. For years it was believed that they share receptor specificity, utilizi... Read More about Canine Respiratory Coronavirus, Bovine Coronavirus, and Human Coronavirus OC43: Receptors and Attachment Factors.