Skip to main content

Research Repository

Advanced Search

Outputs (37)

The architecture of cancellous bone in the hindlimb of moa (Aves: Dinornithiformes), with implications for stance and gait (2019)
Journal Article
Bishop, P. J., Scofield, R. P., & Hocknull, S. A. (2019). The architecture of cancellous bone in the hindlimb of moa (Aves: Dinornithiformes), with implications for stance and gait. https://doi.org/10.1080/03115518.2019.1594380

The extinct, flightless moa of New Zealand included some of the largest birds to have existed and possessed many distinguishing pelvic and hindlimb osteological features. These features may have influenced stance and gait in moa compared with extant... Read More about The architecture of cancellous bone in the hindlimb of moa (Aves: Dinornithiformes), with implications for stance and gait.

Pretectal projections to the oculomotor cerebellum in hummingbirds ( Calypte anna ), zebra finches ( Taeniopygia guttata ), and pigeons ( Columba livia ) (2019)
Journal Article
Gaede, A. H., Gutierrez‐Ibanez, C., Armstrong, M. S., Altshuler, D. L., & Wylie, D. R. (2019). Pretectal projections to the oculomotor cerebellum in hummingbirds ( Calypte anna ), zebra finches ( Taeniopygia guttata ), and pigeons ( Columba livia ). Journal of Comparative Neurology, 527(16), 2644-2658. https://doi.org/10.1002/cne.24697

In birds, optic flow is processed by a retinal‐recipient nucleus in the pretectum, the nucleus lentiformis mesencephali (LM), which then projects to the cerebellum, a key site for sensorimotor integration. Previous studies have shown that the LM is h... Read More about Pretectal projections to the oculomotor cerebellum in hummingbirds ( Calypte anna ), zebra finches ( Taeniopygia guttata ), and pigeons ( Columba livia ).

Spontaneous dog osteoarthritis — a One Medicine vision (2019)
Journal Article
Meeson, R. L., Todhunter, R. J., Blunn, G., Nuki, G., & Pitsillides, A. A. (2019). Spontaneous dog osteoarthritis — a One Medicine vision. Nature Reviews Rheumatology, 15(5), 273-287. https://doi.org/10.1038/s41584-019-0202-1

Osteoarthritis (OA) is a global disease that, despite extensive research, has limited treatment options. Pet dogs share both an environment and lifestyle attributes with their owners, and a growing awareness is developing in the public and among rese... Read More about Spontaneous dog osteoarthritis — a One Medicine vision.

Relating neuromuscular control to functional anatomy of limb muscles in extant archosaurs (2019)
Journal Article
Cuff, A. R., Daley, M. A., Michel, K. B., Allen, V. R., Lamas, L. P., Adami, C., Monticelli, P., Pelligand, L., & Hutchinson, J. R. (2019). Relating neuromuscular control to functional anatomy of limb muscles in extant archosaurs. Journal of Morphology, 280(5), 666-680. https://doi.org/10.1002/jmor.20973

Electromyography (EMG) is used to understand muscle activity patterns in animals. Understanding how much variation exists in muscle activity patterns in homologous muscles across animal clades during similar behaviours is important for evaluating the... Read More about Relating neuromuscular control to functional anatomy of limb muscles in extant archosaurs.

Terrestrial mammalian wildlife responses to Unmanned Aerial Systems approaches (2019)
Journal Article
Bennitt, E., Bartlam-Brooks, H. L. A., Hubel, T. Y., & Wilson, A. M. (2019). Terrestrial mammalian wildlife responses to Unmanned Aerial Systems approaches. https://doi.org/10.1038/s41598-019-38610-x

Unmanned Aerial Systems (UAS) are increasingly being used recreationally, commercially and for wildlife research, but very few studies have quantified terrestrial mammalian reactions to UAS approaches. We used two Vertical Take-off and Landing (VTOL)... Read More about Terrestrial mammalian wildlife responses to Unmanned Aerial Systems approaches.

The running kinematics of free-roaming giraffes, measured using a low cost unmanned aerial vehicle (UAV) (2019)
Journal Article
Basu, C. K., Deacon, F., Hutchinson, J. R., & Wilson, A. M. (2019). The running kinematics of free-roaming giraffes, measured using a low cost unmanned aerial vehicle (UAV). PeerJ, 7, e6312. https://doi.org/10.7717/peerj.6312

The study of animal locomotion can be logistically challenging, especially in the case of large or unhandleable animals in uncontrolled environments. Here we demonstrate the utility of a low cost unmanned aerial vehicle (UAV) in measuring two-dimensi... Read More about The running kinematics of free-roaming giraffes, measured using a low cost unmanned aerial vehicle (UAV).

Pituitary gland abscess in a horse subsequent to head trauma (2019)
Journal Article
Morgan, R. E., Fiske-Jackson, A. R., & Biggi, M. (2019). Pituitary gland abscess in a horse subsequent to head trauma. Equine Veterinary Education, https://doi.org/10.1111/eve.13043

A 5‐year‐old Thoroughbred gelding with recent history of head trauma presented with multiple facial swellings, bilateral mucopurulent nasal discharge, neck pain, inappetence and depression. On computed tomographic examination, lesions within the pitu... Read More about Pituitary gland abscess in a horse subsequent to head trauma.

Parsimonious test of dynamic interaction (2019)
Journal Article
Chisholm, S., Stein, A. B., Jordan, N. R., Hubel, T. Y., Shawe-Taylor, J., Fearn, T., McNutt, J. W., Wilson, A. M., & Hailes, S. (2019). Parsimonious test of dynamic interaction. Ecology and Evolution, https://doi.org/10.1002/ece3.4805

In recent years, there have been significant advances in the technology used to collect data on the movement and activity patterns of humans and animals. GPS units, which form the primary source of location data, have become cheaper, more accurate, l... Read More about Parsimonious test of dynamic interaction.

Isolation and generation of osteoblasts (2019)
Book Chapter
Perpetuo, I. P., Bourne, L. E., & Orriss, I. R. (2019). Isolation and generation of osteoblasts. In Bone Research Protocols. Humana Press. https://doi.org/10.1007/978-1-4939-8997-3_2

This chapter describes the isolation, culture, and staining of osteoblasts. The key advantages of this assay are that it allows direct measurement of bone matrix deposition and mineralization, as well as yielding good quantities of osteoblasts at def... Read More about Isolation and generation of osteoblasts.

Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment (2019)
Journal Article
Betts, C. A., McClorey, G., Healicon, R., Hammond, S. M., Manzano, R., Muses, S., Ball, V., Godfrey, C., Merritt, T. M., Westering, T., O'Donovan, L., Wells, K. E., Gait, M. J., Wells, D. J., Tyler, D., & Wood, M. J. (2019). Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment. Human Molecular Genetics, 28(3), 396-406. https://doi.org/10.1093/hmg/ddy346

Duchenne muscular dystrophy (DMD) is caused by loss of dystrophin protein, leading to progressive muscle weakness and premature death due to respiratory and/or cardiac complications. Cardiac involvement is characterized by progressive dilated cardiom... Read More about Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment.

Sost haploinsufficiency provokes peracute lethal cardiac tamponade without rescuing the osteopenia in a mouse model of excess glucocorticoids (2019)
Journal Article
Javaheri, B., Herbert, E., Hopkinson, M., Al-Jazzar, A., & Pitsillides, A. A. (2019). Sost haploinsufficiency provokes peracute lethal cardiac tamponade without rescuing the osteopenia in a mouse model of excess glucocorticoids. American Journal of Pathology, 189(4), 753-761. https://doi.org/10.1016/j.ajpath.2018.12.007

Glucocorticoid-induced secondary osteoporosis is the most predictable side-effect of this anti-inflammatory. One of the main mechanisms by which glucocorticoids achieve such deleterious outcome in bone is by antagonizing Wnt/β-catenin signalling. Scl... Read More about Sost haploinsufficiency provokes peracute lethal cardiac tamponade without rescuing the osteopenia in a mouse model of excess glucocorticoids.

Reverse-engineering the locomotion of a stem amniote (2019)
Journal Article
Nyakatura, J. A., Melo, K., Horvat, T., Karakasiliotis, K., Allen, V. R., Andikfar, A., Andrada, E., Arnold, P., Lauströer, J., Hutchinson, J. R., Fischer, M. S., & Ijspeert, A. J. (2019). Reverse-engineering the locomotion of a stem amniote. Nature, 565, 351-355. https://doi.org/10.1038/s41586-018-0851-2

Reconstructing the locomotion of extinct vertebrates offers insights into their palaeobiology and helps to conceptualize major transitions in vertebrate evolution. However, estimating the locomotor behaviour of a fossil species remains a challenge be... Read More about Reverse-engineering the locomotion of a stem amniote.

The locomotor kinematics and ground reaction forces of walking giraffes. (2019)
Journal Article
Basu, C. K., Wilson, A. M., & Hutchinson, J. R. (2019). The locomotor kinematics and ground reaction forces of walking giraffes. Journal of Experimental Biology, 222(22), https://doi.org/10.1242/jeb.159277

Giraffes (Giraffa camelopardalis Linnaeus 1758) possess specialised anatomy. Their disproportionately elongate limbs and neck confer recognised feeding advantages, but little is known about how their morphology affects locomotor function. In this stu... Read More about The locomotor kinematics and ground reaction forces of walking giraffes..