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Outputs (1267)

Foot pressure distributions during walking in African elephants (Loxodonta africana) (2016)
Journal Article
Panagiotopoulou, O., Pataky, T. C., Day, M., Hensman, S., Hutchinson, J. R., & Clemente, C. J. (2016). Foot pressure distributions during walking in African elephants (Loxodonta africana). Royal Society Open Science, 3(10), 160203. https://doi.org/10.1098/rsos.160203

Elephants, the largest living land mammals, have evolved a specialized foot morphology to help reduce locomotor pressures while supporting their large body mass. Peak pressures that could cause tissue damage are mitigated passively by the anatomy of... Read More about Foot pressure distributions during walking in African elephants (Loxodonta africana).

Comparison of clinical signs and outcomes between dogs with presumptive ischemic myelopathy and dogs with acute non compressive nucleus pulposus extrusion (2016)
Journal Article
Fenn, J. T., Drees, R., Volk, H. A., & De Decker, S. (2016). Comparison of clinical signs and outcomes between dogs with presumptive ischemic myelopathy and dogs with acute non compressive nucleus pulposus extrusion. Journal of the American Veterinary Medical Association, 249(7), 767-775. https://doi.org/10.2460/javma.249.7.767

Growth differentiation factor-15 is associated with muscle mass in chronic obstructive pulmonary disease and promotes muscle wasting in vivo (2016)
Journal Article
Patel, M. S., Lee, J., Baz, M., Wells, C. E., Bloch, S., Lewis, A., Donaldson, A. V., Garfield, B. E., Hopkinson, N. S., Natanek, A., Man, W. D. C., Wells, D. J., Baker, E. H., Polkey, M. I., & Kemp, P. R. (2016). Growth differentiation factor-15 is associated with muscle mass in chronic obstructive pulmonary disease and promotes muscle wasting in vivo. Journal of Cachexia, Sarcopenia and Muscle, 7(4), 436-448. https://doi.org/10.1002/jcsm.12096

Flight of the dragonflies and damselflies (2016)
Journal Article
Bomphrey, R. J., Nakata, T., Henningsson, P., & Lin, H.-T. (2016). Flight of the dragonflies and damselflies. Philosophical Transactions of the Royal Society B: Biological Sciences, 371(1704), 20150389. https://doi.org/10.1098/rstb.2015.0389

This work is a synthesis of our current understanding of the mechanics, aerodynamics and visually mediated control of dragonfly and damselfly flight, with the addition of new experimental and computational data in several key areas. These are: the di... Read More about Flight of the dragonflies and damselflies.

Transgenic Rescue of the LARGEmyd Mouse: A LARGE Therapeutic Window? (2016)
Journal Article
Hildyard, J. C. W., Lacey, E., Booler, H., Hopkinson, M., Wells, D. J., & Brown, S. C. (2016). Transgenic Rescue of the LARGEmyd Mouse: A LARGE Therapeutic Window?. PLoS ONE, 11(7), e0159853. https://doi.org/10.1371/journal.pone.0159853

LARGE is a glycosyltransferase involved in glycosylation of α-dystroglycan (α-DG). Absence of this protein in the LARGEmyd mouse results in α-DG hypoglycosylation, and is associated with central nervous system abnormalities and progressive muscular d... Read More about Transgenic Rescue of the LARGEmyd Mouse: A LARGE Therapeutic Window?.

Degree of Cajal-Retzius cell mislocalisation correlates with the severity of structural brain defects in mouse models of dystroglycanopathy (2016)
Journal Article
Booler, H., Williams, J., Hopkinson, M., & Brown, S. C. (2016). Degree of Cajal-Retzius cell mislocalisation correlates with the severity of structural brain defects in mouse models of dystroglycanopathy. Brain Pathology, 26(4), 465-478. https://doi.org/10.1111/bpa.12306

The secondary dystroglycanopathies are characterized by the hypoglycosylation of alpha dystroglycan, and are associated with mutations in at least 18 genes that act on the glycosylation of this cell surface receptor rather than the Dag1 gene itself.... Read More about Degree of Cajal-Retzius cell mislocalisation correlates with the severity of structural brain defects in mouse models of dystroglycanopathy.

Evaluation of magnetic resonance imaging guidelines for differentiation between thoracolumbar intervertebral disk extrusions and intervertebral disk protrusions in dogs (2016)
Journal Article
De Decker, S., Gomes, S. A., Packer, R. M. A., Kenny, P. J., Beltran, E., Parzefall, B., Fenn, J. T., Nair, D., Nye, G., & Volk, H. A. (2016). Evaluation of magnetic resonance imaging guidelines for differentiation between thoracolumbar intervertebral disk extrusions and intervertebral disk protrusions in dogs. https://doi.org/10.1111/vru.12394

Four MRI variables have recently been suggested to be independently associated with a diagnosis of thoracolumbar intervertebral disk extrusion or protrusion. Midline intervertebral disk herniation, and partial intervertebral disk degeneration were as... Read More about Evaluation of magnetic resonance imaging guidelines for differentiation between thoracolumbar intervertebral disk extrusions and intervertebral disk protrusions in dogs.

Neurodegeneration and Epilepsy in a Zebrafish Model of CLN3 Disease (Batten Disease) (2016)
Journal Article
Wager, K., Zdebik, A. A., Fu, S., Cooper, J. D., Harvey, R. J., & Russell, C. (2016). Neurodegeneration and Epilepsy in a Zebrafish Model of CLN3 Disease (Batten Disease). PLoS ONE, 11(6), https://doi.org/10.1371/journal.pone.0157365

The neuronal ceroid lipofuscinoses are a group of lysosomal storage disorders that comprise the most common, genetically heterogeneous, fatal neurodegenerative disorders of children. They are characterised by childhood onset, visual failure, epilepti... Read More about Neurodegeneration and Epilepsy in a Zebrafish Model of CLN3 Disease (Batten Disease).