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Morphology and the gradient of a symmetric potential predicts gait transitions of dogs (2017)
Journal Article
Wilshin, S. D., Haynes, G. C., Porteous, J., Koditschek, D., Revzen, S., & Spence, A. J. (2017). Morphology and the gradient of a symmetric potential predicts gait transitions of dogs. Biological Cybernetics, 111(3-4), 269-277. https://doi.org/10.1007/s00422-017-0721-2

Gaits and gait transitions play a central role in the movement of animals. Symmetry is thought to govern the structure of the nervous system, and constrain the limb motions of quadrupeds. We quantify the symmetry of dog gaits with respect to combinat... Read More about Morphology and the gradient of a symmetric potential predicts gait transitions of dogs.

Finite-element modelling of mechanobiological factors influencing sesamoid tissue morphology in the patellar tendon of an ostrich (2017)
Journal Article
Chadwick, K., Shefelbine, S. J., Pitsillides, A. A., & Hutchinson, J. R. (2017). Finite-element modelling of mechanobiological factors influencing sesamoid tissue morphology in the patellar tendon of an ostrich. Royal Society Open Science, 4(6), 170133. https://doi.org/10.1098/rsos.170133

The appearance and shape of sesamoid bones within a tendon or ligament wrapping around a joint are understood to be influenced by both genetic and epigenetic factors. Ostriches (Struthio camelus) possess two sesamoid patellae (kneecaps), one of which... Read More about Finite-element modelling of mechanobiological factors influencing sesamoid tissue morphology in the patellar tendon of an ostrich.

Activation of the P2Y2 receptor regulates bone cell function by enhancing ATP release (2017)
Journal Article
Orriss, I. R., Gueneri, D., Hajjawai, M. O., Shaw, K., Patel, J. J., & Arnett, T. R. (2017). Activation of the P2Y2 receptor regulates bone cell function by enhancing ATP release. Journal of Endocrinology, 233, 341-356. https://doi.org/10.1530/JOE-17-0042

Bone cells constitutively release ATP into the extracellular environment where it acts locally via P2 receptors to regulate bone cell function. Whilst P2Y2 receptor stimulation regulates bone mineralisation, the functional effects of this receptor in... Read More about Activation of the P2Y2 receptor regulates bone cell function by enhancing ATP release.

Suite of simple metrics reveals common movement syndromes across vertebrate taxa (2017)
Journal Article
Abrahms, B., Seidel, D. P., Dougherty, E., Hazen, E. L., Bograd, S. J., Wilson, A. M., Weldon McNutt, J., Costa, D. P., Blake, S., Brashares, J. S., & Getz, W. M. (2017). Suite of simple metrics reveals common movement syndromes across vertebrate taxa. Movement Ecology, 5(12), https://doi.org/10.1186/s40462-017-0104-2

ecause empirical studies of animal movement are most-often site- and species-specific, we lack understanding of the level of consistency in movement patterns across diverse taxa, as well as a framework for quantitatively classifying movement patterns... Read More about Suite of simple metrics reveals common movement syndromes across vertebrate taxa.

Inverse dynamic modelling of jumping in the red-legged running frog Kassina maculata (2017)
Journal Article
Porro, L. B., Collings, A. J., Eberhard, E. A., Chadwick, K. P., & Richards, C. T. (2017). Inverse dynamic modelling of jumping in the red-legged running frog Kassina maculata. Journal of Experimental Biology, 220, 1882-1893. https://doi.org/10.1242/jeb.155416

Although the red-legged running frog, Kassina maculata, is secondarily a walker/runner, it retains the capacity for multiple locomotor modes, including jumping at a wide range of angles (nearly 70 deg). Using simultaneous hind limb kinematics and sin... Read More about Inverse dynamic modelling of jumping in the red-legged running frog Kassina maculata.

Hypomorphic conditional deletion of E11/Podoplanin reveals a role in osteocyte dendrite elongation (2017)
Journal Article
Staines, K. A., Javaheri, B., Hohenstein, P., Fleming, R., Ikpegbu, E., Unger, E., Hopkinson, M., Buttle, D. J., Pitsillides, A. A., & Farquharson, C. (2017). Hypomorphic conditional deletion of E11/Podoplanin reveals a role in osteocyte dendrite elongation. Journal of Cellular Physiology, 232(11), 3006-3019. https://doi.org/10.1002/jcp.25999

The transmembrane glycoprotein E11/Podoplanin (Pdpn) has been implicated in the initial stages of osteocyte differentiation. However, its precise function and regulatory mechanisms are still unknown. Due to the known embryonic lethality induced by gl... Read More about Hypomorphic conditional deletion of E11/Podoplanin reveals a role in osteocyte dendrite elongation.

Detection of early osteogenic commitment in primary cells using Raman spectroscopy (2017)
Journal Article
Smith, S. J., Emery, R., Pitsillides, A. A., Clarkin, C. E., & Mahajan, S. (2017). Detection of early osteogenic commitment in primary cells using Raman spectroscopy. Analyst, 142(11), 1962-1973. https://doi.org/10.1039/C6AN02469F

Major challenges in the development of novel implant surfaces for artificial joints include osteoblast heterogeneity and the lack of a simple and sensitive in vitro assay to measure early osteogenic responses. Raman spectroscopy is a label-free, non-... Read More about Detection of early osteogenic commitment in primary cells using Raman spectroscopy.

Clinical reasoning in feline epilepsy: Which combination of clinical information is useful? (2017)
Journal Article
Stanciu, G. D., Packer, R. M. A., Pakozdy, A., Solcan, G., & Volk, H. A. (2017). Clinical reasoning in feline epilepsy: Which combination of clinical information is useful?. https://doi.org/10.1016/j.tvjl.2017.04.001

We sought to identify the association between clinical risk factors and the diagnosis of idiopathic epilepsy (IE) or structural epilepsy (SE) in cats, using statistical models to identify combinations of discrete parameters from the patient signalmen... Read More about Clinical reasoning in feline epilepsy: Which combination of clinical information is useful?.

Head and pelvic movement asymmetries at trot in riding horses in training and perceived as free from lameness by the owner (2017)
Journal Article
Rhodin, M., Egenvall, A., Haubro Andersen, P., & Pfau, T. (2017). Head and pelvic movement asymmetries at trot in riding horses in training and perceived as free from lameness by the owner. PLoS ONE, 12(4), e0176253. https://doi.org/10.1371/journal.pone.0176253

Recent studies evaluating horses in training and considered free from lameness by their owners have identified a large proportion of horses with motion asymmetries. However the prevalence, type and magnitude of asymmetries when trotting in a straight... Read More about Head and pelvic movement asymmetries at trot in riding horses in training and perceived as free from lameness by the owner.

Terrestrial capture of prey by the reedfish, a model species for stem tetrapods (2017)
Journal Article
Van Wassenbergh, S., Bonte, C., & Michel, K. B. (2017). Terrestrial capture of prey by the reedfish, a model species for stem tetrapods. Ecology and Evolution, 7(11), 3856-3860. https://doi.org/10.1002/ece3.2694

Due to morphological resemblance, polypterid fishes are used as extant analogues of Late Devonian lobe‐finned sarcopterygians to identify the features that allowed the evolution of a terrestrial lifestyle in early tetrapods. Previous studies using po... Read More about Terrestrial capture of prey by the reedfish, a model species for stem tetrapods.

Smart wing rotation and trailing-edge vortices enable high frequency mosquito flight (2017)
Journal Article
Bomphrey, R. J., Nakata, T., Phillips, N., & Walker, S. M. (2017). Smart wing rotation and trailing-edge vortices enable high frequency mosquito flight. Nature, 544, 92-95. https://doi.org/10.1038/nature21727

Mosquitoes exhibit unusual wing kinematics; their long, slender wings flap at remarkably high frequencies for their size (>800 Hz)and with lower stroke amplitudes than any other insect group1. This shifts weight support away from the translation-domi... Read More about Smart wing rotation and trailing-edge vortices enable high frequency mosquito flight.